We narrowed to 391 results for: ARIA;

... in human cells. Thus, they engineered two CBE variants with mutations in the rat APOBEC1 that decreases...

...however nuclear translocation rates are another variable to consider when designing KTR experiments. Third...

...Inhibitory (Hyperpolarizing) ChR Variants Alternatively, ChR variants that inhibit neurons have been created... these variants result in the hyperpolarization of neurons. Examples of anion channel variants from other...Mac and its variants allow for inhibition of neurons using blue-green light. Mac variants have been engineered... eMac3.0 Glossary of Microbial Opsin Variants Opsin Type Variant Description Peak Response Spectra (nm...Phobos Blue-shifted iC++ variant 467 Aurora Red-shifted anion-selective ReaChR variant 517 Halorhodopsins Jaws...wild-type opsin of each and some examples of relevant variants. This list is not exhaustive — please browse our...to the membrane. Excitatory (Depolarizing) ChR Variants The optogenetic toolbox has been expanded by scientists...

... they’ve engineered SECURE adenine base editor variants using a protein-truncation strategy with reduced...

...results of Myriad's genetic tests for breast and ovarian cancer risk directly from customers. 6)      An...

...erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science 2013...

.... In particular, they’re focused on generating variants with improved affinity and dynamic range of both...

... other orthologs. Ma et al. tested their dCas9 variants using gRNAs specific for telomeric sequences and...

...binding) SpCas9 VRER variant 3' NGCG SpCas9 EQR variant 3' NGAG SpCas9 VQR variant 3' NGAN or NGNG xCas9...LbCpf1) 5' TTTV AsCpf1 RR variant 5' TYCV LbCpf1 RR variant 5' TYCV AsCpf1 RVR variant 5' TATV Campylobacter...Species/Variant of Cas9 PAM Sequence* Streptococcus pyogenes (SP); SpCas9 3' NGG SpCas9 D1135E variant 3' ...use, and there are several to choose from. Many variations of Cas9 exist, along with other Cas enzymes like... PAM-flexible or PAMless Cas9s. SpCas9-derived variants with non-NGG PAM sequences include: xCas9 — NG...plant genome engineering. Read more about Cas9 variants . Anti-CRISPR Prolonged Cas9 activity can increase...systems create a wide spectrum of single-nucleotide variants (somatic hypermutation) in a larger editing window...

...Tris-EDTA (TE), just Tris buffer, or some other variations. Does it make a difference? Short answer: yes...

...length of the truncated attP site. The three SPARC variants, based on the length of the attP site, allow for...

...Hub What is a Virus (and a Viral Vector)?  AAV Variables that Matter...

... is composed of identical repeat sequences and variable spacer sequences. The array is transcribed and...

... line knock-ins of patient mutations which are variants of unknown significance – mutations with unclear...

...in moderate thermophiles.  These evolved SpCas9 variants have improved activity on NAG PAMS and reduced...

...CRISPR Antimicrobials Day 7: Multiplexing and Cas9 variants: CRISPR 101: Multiplex Expression of gRNAs and...

...Addgene, positively affect scientific research. As Maria Castro of University of Michigan says, “Addgene ...

...components, and challenging target genomes, such as the malaria-causing Plasmodium falciparum. Throughout these...

...variety of science concepts. From inheritance and variation, to growth and development, and response to environment...

...Check out this post to see if an engineered Cas9 variant might work for your experiment. PITChing MMEJ as...