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Using synthetic biology principles has simplified and improved plasmids for optogenetic control of gene expression in E. coli.

Learn about how CRISPR systems are classified. Addgene's guide to typing CRISPR.

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

The science community has gotten pretty good at sharing open software. But sharing open hardware brings its own unique challenges and solutions.

Looking for a way to study integrins? IPI's first deposit, a toolset comprised of anti-integrin antibodies, is now available in Addgene's repository!

Discover the tools you need to perform plant genome engineering with CRISPR.

An end of year list of 12 CRISPR resources available on Addgene, focusing on ones added in 2021.

Use CRISPRainbow to label multiple genome sites with fluorescent proteins of various colors.

An introduction to transposons including Sleeping Beauty, piggyBac, and Tol2 and how they can be used in transposon mutagenesis screens, gene transfer, and creating transgenic animals.

Learn how you can use planarian plasmids from the Sánchez lab to teach developmental biology techniques to new molecular biologists.

Determine the number of genome-containing particles in an AAV prep using qPCR, SYBR Green Technology, and Addgene’s AAV Titration protocol.

Addgene's antibody lab member Kate describes each step in recombinant antibody production process.

PRIDICT 2.0 is an updated software that can help you design gRNAs for PRIME editing. Read more in our guest post!

A review of the common antibiotic resistances genes used in bacteria.

Lentiviruses are useful for delivering DNA sequences to non-dividing mammalian cells. Learn all about the components of lentiviral vectors inside.

Fluorescent proteins can mis-fold or form aggregates outside of the cytoplasm leading to errors in localization. Avoid these issues with new mOX-FPs.

Developments in light sheet fluorescence microscopy (LSFM) and tissue clearing enable researchers to visualize tissues of transgenic and non-transgenic organisms in 3D.

Addgene Board Member Connie Cepko gives us the scoop on progress in retinal gene therapies and the development of GFP-activatable tools in her lab.

Curious about how, exactly, Cas9 does what it does? Dive into the structural biology of Cas9 for an answer!

We describe the different modular cloning kits available for different applications and organisms to help you find the kit that's right for your experiment.