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We narrowed to 85 results for: Apoe;

Showing: 21 - 40 of 85 results
  1. Addgene's Cancer Collection Pages Connect the Research Community

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    Blog Post
    ...awry. The process of programmed cell death, or apoptosis, is one such mechanism. When a cell or its genetic...that cell will most often commit itself to the apoptotic pathway and be eliminated from the body. In the...the case of cancer, however, the apoptotic pathway is circumvented because of the specific genes involved...
  2. Great Results Start with Great Standard Curves

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    Blog Post
    ...versus the response and use that information to extrapolate the concentration of an unknown sample. For example...sigmoidal. Once the trendline is calculated, you can extrapolate the concentration of the unknown sample based...sample is determined by using the trendline to extrapolate its x value, 0.963 mg/mL, from its y value, 0.651...
  3. Antibodies 101: The Four ELISAs and When to Use Them

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    Blog Post
    ...of the sample to that of a standard curve to extrapolate the concentration of antigen in the sample. A... present in the sample and is calculated by extrapolating from the standard curve. Because the primary... present in the sample and is calculated by extrapolating from the standard curve. Scientists often opt...
  4. Targeting HIV-1 with CRISPR: Shock and Kill or Cut it Out?

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    Blog Post
    ... HIV-1 toxic proteins, CRISPR/Cas9 SAM caused apoptosis, indicating a true “shock and kill” response. ...on cell viability, cell cycle progression, or apoptosis with Cas9/gRNA expression. A pooled analysis found...Addgene. Kaminski R, Chen Y, Fischer T, Tedaldi E, Napoli A, Zhang Y, Karn J, Hu W, Khalili K. Elimination...
  5. What's New in CRISPR - May 2019

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    Blog Post
    ...found that a cytosine base editor (CBE) with rat APOBEC1 causes genome-wide deamination of RNA cytosines...engineered two CBE variants with mutations in the rat APOBEC1 that decreases the number of off-target RNA edits...
  6. Viral Vectors 101: Chemogenetics

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    Blog Post
    ...Varenicline has been further modified to create ultrapotent PSEMS (uPSEMs) that have drastically increased... A, Basu J, Michaelides M, Sternson S (2019) Ultrapotent chemogenetics for research and potential clinical...
  7. Experimenting with New Careers while in Grad School

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    Blog Post
    ... myidp.sciencecareers.org mentioned museums. Indianapolis is home to one of "The world’s biggest and best...children’s museum", The Children's Museum of Indianapolis. I drove passed these dinosaurs every day. They...
  8. 8 Great Depositor Research Stories

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    Blog Post
    ...directed DNA Demethylation: Guest blogger Daniel M. Sapozhnikov tells us how to use dCas9 (with no modifications...
  9. Antibodies 101: Epitope Tags

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    Blog Post
    ... as well. This tag is not suitable for use in apoptotic cells as Caspase3/7 both cleave after the DVPD...
  10. The Strength of Story Telling

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    Blog Post
    ...it for a while and he eventually calmed down, apologised and admitted he’d been under a lot of pressure...
  11. Hot Plasmids - January 2023

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    Blog Post
    ...  After using mCherry for FACS sorting of the weaponized T-cells (CAR-T cells) - and then delivering them...
Showing: 21 - 40 of 85 results