We narrowed to 278 results for: HTT

...and its host response. Nat Methods 13:868–874 . https://doi.org/10.1038/nmeth.3993  Cong L, Ran FA, Cox... Using CRISPR/Cas Systems. Science 339:819–823 .https://doi.org/10.1126/science.1231143  Cox DBT, Gootenberg...editing with CRISPR-Cas13. Science 358:1019–1027 . https://doi.org/10.1126/science.aaq0180  Fine EJ, Appleton...using compact expression cassettes. Sci Rep 5: . https://doi.org/10.1038/srep10777  Garneau JE, Dupuis ...bacteriophage and plasmid DNA. Nature 468:67–71 . https://doi.org/10.1038/nature09523  Ibraheim R, Song ...Neisseria meningitidis Cas9 in vivo. Genome Biol 19: . https://doi.org/10.1186/s13059-018-1515-0  Kim E, Koo ...derived from Campylobacter jejuni. Nat Commun 8: . https://doi.org/10.1038/ncomms14500  Levy JM, Yeh W-H,...

... editing. Nature Biotechnology, 41(5), 663–672. https://doi.org/10.1038/s41587-022-01532-7 Gaudelli, N...without DNA cleavage. Nature, 551(7681), 464–471. https://doi.org/10.1038/nature24644 Gaudelli, N. M., Lam...application. Nature Biotechnology, 38(7), 892–900. https://doi.org/10.1038/s41587-020-0491-6 Grünewald, J... editing. Nature Biotechnology, 38(7), 861–864. https://doi.org/10.1038/s41587-020-0535-y Kim, Y. B., ... fusions. Nature Biotechnology, 35(4), 371–376. https://doi.org/10.1038/nbt.3803 Koblan, L. W., Doman,...reconstruction. Nature Biotechnology, 36(9), 843–846. https://doi.org/10.1038/nbt.4172 Komor, A. C., Kim, Y....double-stranded DNA cleavage. Nature, 533(7603), 420–424. https://doi.org/10.1038/nature17946 Komor, A. C., Zhao...

...conservation of a conoid. PLoS Biology 19:e3001020. https://doi.org/10.1371/journal.pbio.3001020  Chen F, ...2015) Expansion microscopy. Science 347:543–548. https://doi.org/10.1126/science.1260088 Damstra HG, Mohar...Robust Expansion Microscopy (TREx). Elife 11:e73775. https://doi.org/10.7554/elife.73775  Dani A, Huang B, ...Chemical Synapses in the Brain. Neuron 68:843–856. https://doi.org/10.1016/j.neuron.2010.11.021  Gambarotto...expansion microscopy (U-ExM). Nat Methods 16:71–74. https://doi.org/10.1038/s41592-018-0238-1  Klimas A, Gallagher... for expansion microscopy. Nat Biotechnol 1–12. https://doi.org/10.1038/s41587-022-01546-1  Mikhaylova...using anti-tubulin nanobodies. Nat Commun 6:7933. https://doi.org/10.1038/ncomms8933  M’Saad O, Bewersdorf...

... Caenorhabditis elegans. Genetics 198:837–846 . https://doi.org/10.1534/genetics.114.169730 Bottcher R...Drosophila cells. Nucleic Acids Research 42:e89–e89 . https://doi.org/10.1093/nar/gku289 Chen C, Fenk LA, de...recombination. Nucleic Acids Research 41:e193–e193 . https://doi.org/10.1093/nar/gkt805 Dickinson DJ, Pani ...Drug Selection Cassette. Genetics 200:1035–1049 . https://doi.org/10.1534/genetics.115.178335 Dokshin GA... Caenorhabditis elegans. Genetics 210:781–787 . https://doi.org/10.1534/genetics.118.301532 Ebbing A, ...alternative gene editing system for AT-rich sequences https://doi.org/10.17912/W2237D Farboud B, Severson AF...Editing Using CRISPR-Cas9. Genetics 211:431–457 . https://doi.org/10.1534/genetics.118.301775 Ghanta KS,...

...null,"href":"https://www.addgene.org/collections/mammalianrnai/","href_with_scheme":"https://www.addgene.org...D. P. (2004). MicroRNAs. Cell, 116(2), 281–297. https://doi.org/10.1016/s0092-8674(04)00045-5 De Rie, ...and mouse. Nature Biotechnology, 35(9), 872–878. https://doi.org/10.1038/nbt.3947 Fire, A., Xu, S., Montgomery...Caenorhabditis elegans. Nature, 391(6669), 806–811. https://doi.org/10.1038/35888  Iwakawa, H., & Tomari, ...silencing complex. Molecular Cell, 82(1), 30–43. https://doi.org/10.1016/j.molcel.2021.11.026 Kilikevicius...silencing. Nucleic Acids Research, 50(2), 617–634. https://doi.org/10.1093/nar/gkab1256 Lee, Y., Kim, M.,...polymerase II. The EMBO Journal, 23(20), 4051–4060. https://doi.org/10.1038/sj.emboj.7600385 McIntyre, G. ...

...native viral promoters. Mol Ther, 7(4), 526–534. https:/doi.org/10.1016/S1525-0016(03)00023-6. PMID: 12727116...evidence. Emerg Microbes Infect, 8(1), 1679–1687. https://doi.org/10.1080/22221751.2019.1690953. PMID: 31749409...Reference Module in Biomedical Sciences. Elsevier. https://doi.org/10.1016/B978-0-12-801238-3.02523-X. Hofmann...Adenoviruses In Vivo. J Virol, 73(8), 6930–6936. https://doi.org/10.1128/JVI.73.8.6930-6936.1999. PMID:...therapy. Proc Natl Acad Sci U S A, 95(19), 11377. https://doi.org/10.1073/PNAS.95.19.11377. PMID: 9736744...Nuclear Pore Complex. PLoS Pathog, 11(6), e1004821. https://doi.org/10.1371/journal.ppat.1004821. PMID: 26042599...adenoviruses. J Clin Pathol Suppl (R Coll Pathol)., 6, 39. https://doi.org/10.1136/jcp.s3-6.1.39. PMID: 4376152. ...

...The unexhausted potential of E. coli. ELife, 4. https://doi.org/10.7554/elife.05826 Blum, M., & Ott, T...Disease. Cells Tissues Organs, 205(5–6), 303–313. https://doi.org/10.1159/000490898 Gibbs, R., Weinstock...mammalian evolution. Nature 428, 493–521 (2004). https://doi.org/10.1038/nature02426 Iannaccone, P. M.,...! Disease Models & Mechanisms, 2(5–6), 206–210. https://doi.org/10.1242/dmm.002733 Idalia, V.-M. N., &...Pathogenesis and Biotechnological Applications. InTech. https://doi.org/10.5772/67306 Koornneef, M., & Meinke,...model plant. The Plant Journal, 61(6), 909–921. https://doi.org/10.1111/j.1365-313x.2009.04086.x Krämer...ecological context with Arabidopsis thaliana. ELife, 4. https://doi.org/10.7554/elife.06100 Liu, L. S., Zhao, ...

...delivery in mice. J Clin Invest 118:1955–1964 . https://doi.org/10.1172/jci34316 Bak RO, Porteus MH (2017...Using AAV Donor Vectors. Cell Reports 20:750–756 . https://doi.org/10.1016/j.celrep.2017.06.064  Carvalho...Approaches for Retinal Targeting. Front Neurosci 11: . https://doi.org/10.3389/fnins.2017.00503  Chamberlain ...Virus Capsids. Human Gene Therapy Methods 27:1–12 . https://doi.org/10.1089/hgtb.2015.140 Frischmeyer PA (...Lacking Termination Codons. Science 295:2258–2261 . https://doi.org/10.1126/science.1067338 Ghosh A, Yue Y...Transgene-independent Manner. Molecular Therapy 16:124–130 . https://doi.org/10.1038/sj.mt.6300322 Halbert CL, Allen...parts of a larger gene. Nat Biotechnol 20:697–701 . https://doi.org/10.1038/nbt0702-697 Hirsch ML, Agbandje-McKenna...

...using the CRISPR/Cas system. Plant Methods 9:39 . https://doi.org/10.1186/1746-4811-9-39 Gao Q, Xu W, Yan...cereal genomic studies. New Phytol 223:2120–2133 . https://doi.org/10.1111/nph.15889 Gelvin SB (2003) Agrobacterium-Mediated...behind the “Gene-Jockeying” Tool. MMBR 67:16–37 . https://doi.org/10.1128/mmbr.67.1.16-37.2003 Khatodia ...Application in Improvement of Crops. Front Plant Sci 7: . https://doi.org/10.3389/fpls.2016.00506 Kwak S-Y, Lew ...nanotube carriers. Nat Nanotechnol 14:447–455 . https://doi.org/10.1038/s41565-019-0375-4 Lowder LG, Zhang...Transcriptional Regulation. Plant Physiol 169:971–985 . https://doi.org/10.1104/pp.15.00636 Ma X, Zhang X, Liu...virally delivered CRISPR–Cas9. Nat Plants 6:773–779 . https://doi.org/10.1038/s41477-020-0704-5 Santana I, Wu...

...epigenome editing. Nucleic Acids Research 47:e23–e23. https://doi.org/10.1093/nar/gky1286 Hilton IB, D’Ippolito...and enhancers. Nature Biotechnology 33:510–517 . https://doi.org/10.1038/nbt.3199 Find plasmids from this...human genome. Nature Biotechnology 35:561–568 . https://doi.org/10.1038/nbt.3853 Find plasmids from this...-MQ1 fusion protein. Nature Communications 8: . https://doi.org/10.1038/ncomms16026 Find plasmids from...in the Mammalian Genome. Cell 167:233–247.e17 . https://doi.org/10.1016/j.cell.2016.08.056 Find plasmids...fusion proteins. Nature Biotechnology 31:1137–1142 . https://doi.org/10.1038/nbt.2726 Find plasmids from this...site-specific DNA methylation. Biology Open 5:866–874 . https://doi.org/10.1242/bio.019067 Find plasmids from...

...AAV serotypes. Scientific Reports, 15(1), 20927. https://doi.org/10.1038/s41598-025-05518-8 Bish, L. T....and Rat. Human Gene Therapy, 19(12), 1359–1368. https://doi.org/10.1089/hum.2008.123 Dhungel, B. P., Xu...adeno-associated viruses. Cell, S0092-8674(25)00692-0. https://doi.org/10.1016/j.cell.2025.06.026 Halbert, C....Vectors. Journal of Virology, 75(14), 6615–6624. https://doi.org/10.1128/jvi.75.14.6615-6624.2001 Han, ...transduction. Nature Communications, 14(1), 3792. https://doi.org/10.1038/s41467-023-39554-7 Issa, S. S....in Gene Therapy: An Overview. Cells, 12(5), 785. https://doi.org/10.3390/cells12050785 Kaludov, N., Brown...Specificity. Journal of Virology, 75(15), 6884–6893. https://doi.org/10.1128/jvi.75.15.6884-6893.2001 Muraine...

...double-strand breaks or donor DNA. Nature 576:149–157 . https://doi.org/10.1038/s41586-019-1711-4 Avery OT, MacLeod...The Journal of Experimental Medicine 79:137–158 . https://doi.org/10.1084/jem.79.2.137 Carroll D (2011) ...With Zinc-Finger Nucleases. Genetics 188:773–782 . https://doi.org/10.1534/genetics.111.131433 Doudna JA,...engineering with CRISPR-Cas9. Science 346:1258096 . https://doi.org/10.1126/science.1258096 Gaudelli NM, Komor...genomic DNA without DNA cleavage. Nature 559:E8–E8 . https://doi.org/10.1038/s41586-018-0070-x Griffith F (...Pneumococcal Types. Journal of Hygiene 27:113–159 . https://doi.org/10.1017/s0022172400031879 Hershey AD, ...BACTERIOPHAGE. The Journal of General Physiology 36:39–56 . https://doi.org/10.1085/jgp.36.1.39 Komor AC, Kim YB, ...

...for codon usage tables. BMC Bioinformatics 18: . https://doi.org/10.1186/s12859-017-1793-7 Dresios J, Chappell...initiation in eukaryotes. Nat Struct Mol Biol 13:30–34 . https://doi.org/10.1038/nsmb1031 Gustafsson C, Govindarajan...expression. Trends in Biotechnology 22:346–353 . https://doi.org/10.1016/j.tibtech.2004.04.006 Hausser ...inhibit translation. Genome Research 23:604–615 . https://doi.org/10.1101/gr.139758.112 Mauro VP, Chappell...therapeutics. Trends in Molecular Medicine 20:604–613  https://doi.org/10.1016/j.molmed.2014.09.003 Nakamura ... year 2000. Nucleic Acids Research 28:292–292 . https://doi.org/10.1093/nar/28.1.292 Sauna ZE, Kimchi-...mutations to human disease. Nat Rev Genet 12:683–691. https://doi.org/10.1038/nrg3051 Sharp PM, Li W-H (1987...

...using CRISPR–Cas9 screens. Nature 568:511–516 . https://doi.org/10.1038/s41586-019-1103-9 Bialek JK, Dunay...Transcriptional Activator Systems. PLoS ONE 11:e0158294 . https://doi.org/10.1371/journal.pone.0158294 Chari R, ...library-on-library approach. Nat Methods 12:823–826 . https://doi.org/10.1038/nmeth.3473 Chavez A, Scheiman ...transcriptional programming. Nat Methods 12:326–328 . https://doi.org/10.1038/nmeth.3312 Chavez A, Tuttle M,...activators in multiple species. Nat Methods 13:563–567 . https://doi.org/10.1038/nmeth.3871 Gilbert LA, Horlbeck...Gene Repression and Activation. Cell 159:647–661 . https://doi.org/10.1016/j.cell.2014.09.029 Konermann S...engineered CRISPR-Cas9 complex. Nature 517:583–588 . https://doi.org/10.1038/nature14136 Pan J, Meyers RM, ...

...targets. Nature Communications, 7(1), Article 1. https://doi.org/10.1038/ncomms10778  Erdmann, R. S., Baguley...SNAP-tags. Cell Chemical Biology, 26(4), 584-592.e6. https://doi.org/10.1016/j.chembiol.2019.01.003  Gallagher...Reactivity. ACS Chemical Biology, 4(7), 547–556. https://doi.org/10.1021/cb900062k  Gautier, A., Juillerat...Living Cells. Chemistry & Biology, 15(2), 128–136. https://doi.org/10.1016/j.chembiol.2008.01.007  Griffin...Inside Live Cells. Science, 281(5374), 269–272. https://doi.org/10.1126/science.281.5374.269  Jing, C.... Accounts of Chemical Research, 44(9), 784–792. https://doi.org/10.1021/ar200099f  Keppler, A., Gendreizig...molecules in vivo. Nature Biotechnology, 21(1), 1. https://doi.org/10.1038/nbt765  Lavis, L. (2016, September...

...Clinical and Developmental Immunology 2012:1–15 . https://doi.org/10.1155/2012/980250  Bates A, Power CA...Prospects of Antibody Fragments. Antibodies 8:28 . https://doi.org/10.3390/antib8020028  Bird R, Hardman ...antigen-binding proteins. Science 242:423–426 . https://doi.org/10.1126/science.3140379  Bradbury ARM,...display technologies. Nat Biotechnol 29:245–254 . https://doi.org/10.1038/nbt.1791  Deal CE, Balazs AB (...infection. Current Opinion in HIV and AIDS 10:190–197 . https://doi.org/10.1097/coh.0000000000000145  Gąciarz ...intrinsically stable scFv. PLoS ONE 12:e0189964 . https://doi.org/10.1371/journal.pone.0189964  Huston JS...the National Academy of Sciences 85:5879–5883 . https://doi.org/10.1073/pnas.85.16.5879  Leavy O (2016...

...sequence-specific antimicrobials. Nat Biotechnol 32:1146–1150 . https://doi.org/10.1038/nbt.3043 Bikard D, Jiang W, Samai...CRISPR-Cas system. Nucleic Acids Research 41:7429–7437 . https://doi.org/10.1093/nar/gkt520 Citorik RJ, Mimee M...RNA-guided nucleases. Nat Biotechnol 32:1141–1145 . https://doi.org/10.1038/nbt.3011 Cobb RE, Wang Y, Zhao...Engineered CRISPR/Cas System. ACS Synth Biol 4:723–728 . https://doi.org/10.1021/sb500351f Dong C, Fontana J, Patel...transcriptional reprogramming in bacteria. Nat Commun 9: . https://doi.org/10.1038/s41467-018-04901-6 Jiang W, Bikard...CRISPR-Cas systems. Nat Biotechnol 31:233–239 . https://doi.org/10.1038/nbt.2508 Leonard SP, Perutka J...Broad-Host-Range Plasmids. ACS Synth Biol 7:1279–1290 . https://doi.org/10.1021/acssynbio.7b00399 Li Q, Sun B,...

...Photoswitching Proteins (Vol. 2173, pp. 21–51). Springer US. https://doi.org/10.1007/978-1-0716-0755-8_2 Lehtinen, ...Frontiers in Cellular Neuroscience, 15, 778900. https://doi.org/10.3389/fncel.2021.778900 Mattis, J., ...microbial opsins. Nature Methods, 9(2), 159–172. https://doi.org/10.1038/nmeth.1808 References Abreu, N...Photoswitching Proteins (Vol. 2173, pp. 21–51). Springer US. https://doi.org/10.1007/978-1-0716-0755-8_2 Boyden, E....activity. Nature Neuroscience, 8(9), 1263–1268. https://doi.org/10.1038/nn1525 Gunaydin, L. A., Yizhar...optogenetic control. Nature Neuroscience, 13(3), 387–392. https://doi.org/10.1038/nn.2495 Marshel, J. H., Kim, Y...triggering perception. Science, 365(6453), eaaw5202. https://doi.org/10.1126/science.aaw5202 Mattis, J., Tye...

...control of CRISPR–Cas9. Nat Methods 15:924–927 . https://doi.org/10.1038/s41592-018-0178-9  Hemphill J,...Cas9 Gene Editing. J Am Chem Soc 137:5642–5645 . https://doi.org/10.1021/ja512664v  Jain PK, Ramanan V,... Protectors. Angew Chem Int Ed 55:12440–12444 . https://doi.org/10.1002/anie.201606123  Kim JH, Rege M...gene expression control. Nat Methods 16:633–639 . https://doi.org/10.1038/s41592-019-0436-5 Mathony J, Hoffmann...of CRISPR‐Cas9. Angew Chem Int Ed 58:6285–6289 . https://doi.org/10.1002/anie.201900788 Nihongaki Y, Furuhata...neuronal differentiation. Nat Methods 14:963–966 . https://doi.org/10.1038/nmeth.4430 Nihongaki Y, Kawano...optogenetic genome editing. Nat Biotechnol 33:755–760 . https://doi.org/10.1038/nbt.3245 Nihongaki Y, Yamamoto...

...methyl-CpG-binding protein 2. Nat Genet 23:185–188 . https://doi.org/10.1038/13810 Amir RE, Zoghbi HY (2000...phenotype-genotype correlations. Am J Med Genet 97:147–152 . https://doi.org/10.1002/1096-8628(200022)97:2<147::aid-ajmg6...Syndrome and Related Disorders. Cell 152:984–996 . https://doi.org/10.1016/j.cell.2013.01.038 Guy J, Gan ...Model of Rett Syndrome. Science 315:1143–1147 . https://doi.org/10.1126/science.1138389 Le TTH, Tran NT...Human-Induced Pluripotent Stem Cells. Front Genet 10: . https://doi.org/10.3389/fgene.2019.00625 McGraw CM, Samaco... Function Requires MeCP2. Science 333:186–186 . https://doi.org/10.1126/science.1206593 Powers S, Miranda...MeCP2 null (S51.002). Neurology 92 (15 Supplement) . http://n.neurology.org/content/92/15_Supplement/S51.002...