We narrowed to 601 results for: sam

... rg* Ulrik Gether 119741 AAV SYN flex PSAM4 GlyR IRES EGFP PSAM4 GlyR - Inhibition IRES EGFP Cre-dependent...Cre-dependent 5, 9 Scott Sternson 119742 AAV SYN PSAM4 GlyR IRES EGFP PSAM4 GlyR - Inhibition IRES EGFP none 5 Scott...Scott Sternson 119744 AAV CAMKII PSAM4 GlyR IRES EGFP PSAM4 GlyR - Inhibition IRES EGFP none 5 Scott Sternson...Inhibitory HCAD(Gi) DREADD hM4D(Gi) DREADD KOR DREADD PSAM4 GlyR Promoter Synapsin CaMKIIa CD68 Dlx GFAP nEF...

...PSEMs). PSAMs are coupled to an ion pore domain to create a ligand-gated ion channel. Whether a PSAM is activating...chemogenetic experiments, including popular DREADDs and PSAMs. Plasmid...and Pharmacologically Selective Actuator Modules (PSAMs). DREADDs are the most widely used chemogenetic ...activating, while hM4D(Gi) and KORD are inhibitory. PSAMs are engineered α7 nicotinic acetylcholine receptor...it is coupled to. Addgene has two main types of PSAMs: 5HT3 coupled, which are activating, and GlyR-coupled...

...different serotypes. In addition to the standard 100 µL sample size, the vectors listed below are also available...production page . Note: For a list of all 100 µL sized sample, please see our Control AAV Inventory . The catalog...catalog ID for the 20 µL sized testing sample is denoted with a .T suffix (for example, AAV1.T). The catalog...catalog ID for the 100 µL sized sample does not have the suffix (for example, AAV1). AAV Vectors for Serotype...include virus associated DNA (vdna), which is a sample of the purified DNA from the original plasmid that...

...ERBB4 CMV ALS Yardena Samuels 29528 pcDNA3.1-ERBB4 (E317K) ERBB4 CMV ALS Yardena Samuels 29529 pcDNA3.1-ERBB4...ERBB4 CMV ALS Yardena Samuels 29530 pcDNA3.1-ERBB4 (E542K) ERBB4 CMV ALS Yardena Samuels 29531 pcDNA3.1-ERBB4...ERBB4 CMV ALS Yardena Samuels 29532 pcDNA3.1-ERBB4 (E563K) ERBB4 CMV ALS Yardena Samuels 29533 pcDNA3.1-ERBB4...ERBB4 CMV ALS Yardena Samuels 29534 pcDNA3.1-ERBB4 (E836K) ERBB4 CMV ALS Yardena Samuels 29535 pcDNA3.1-ERBB4...ERBB4 CMV ALS Yardena Samuels 29536 pCDF1-ERBB4 WT ERBB4 CMV ALS Yardena Samuels 29537 pCDF1-ERBB4 (E317K...ERBB4 CMV ALS Yardena Samuels 29538 pCDF1-ERBB4 (E452K) ERBB4 CMV ALS Yardena Samuels 29539 pCDF1-ERBB4 (...ERBB4 CMV ALS Yardena Samuels 29540 pCDF1-ERBB4 (R544W) ERBB4 CMV ALS Yardena Samuels 29541 pCDF1-ERBB4 (...

...protein, instead of a two-component system (Figure 9C) SAM activators — co-expression of dCas9-VP64 with a modified... ensures that all gRNAs will be expressed in the same cell. This is called multiplexing , and increases...deletions or inversions with two gRNA sites on the same chromosome. Most multiplex systems enable researchers...sequence ~1 kb shorter than SpCas9 while retaining the same basic function. Its size allows it to be efficiently...from Neisseria meningitidis ), which are about the same size as SaCas9, with higher fidelity than SpCas9... types of base edits: Base transitions — edit to same classification of nucleotide base (purine-to-purine...an enzyme evolved to excise inosine to access the same repair pathway and convert A to any other base. ...

...total protein content of the sample is determined. Only antibody samples with >90% purity are distributed...using a NanoDrop spectrophotometer. If needed, the sample is adjusted by diluting or concentrating to a final...Coomassie staining. For Coomassie staining, the sample is separated via a denaturing SDS-PAGE gel alongside...

...of the viral capsid proteins VP1, VP2 and VP3. Samples of viral preparations are subjected to polyacrylamide...proteins as a fraction of total protein present in the sample is also determined and used to determine purity...shown relative to the total protein present in the sample. Sterility Viral vector preparations are added ...rigorous barcode matching system that follows the sample from the DNA tube all the way to the cleared viral...

...) If the target sites are on the same DNA strand (in cis) in the same direction, the sequence between ...orientation. A) If the target sites (loxP) are on the same DNA strand in opposite directions, recombination...different promoters. Expression of both fragments in the same cell reconstitutes a functional protein, allowing...

...protein and a target-specific gRNA in the same cell at the same time. All-in-one plasmids ensure that both...both the Cas and gRNA are delivered to the same cells, but are limited to the function of the Cas protein...

...Rabies Virus-Based Serotype Serotype Testing Samples Small samples of control AAV vectors for trial purposes...Service overview. Function Chemogenetics DREADDs, PSAMs Optogenetics Channelrhodopsins, Halorhodopsins, ...

...eYFP Viviana Gradinaru 119741-AAV5 AAV SYN flex PSAM4 GlyR IRES EGFP Chemogenetics Cre-dependent expression...plasmid Scott Sternson 119741-AAV9 AAV SYN flex PSAM4 GlyR IRES EGFP Chemogenetics Cre-dependent expression...expression plasmid Scott Sternson 119742-AAV5 AAV SYN PSAM4 GlyR IRES EGFP Chemogenetics expression plasmid ...plasmid Scott Sternson 119744-AAV5 AAV CAMKII PSAM4 GlyR IRES EGFP Chemogenetics expression plasmid Scott Sternson...

...variability in symptoms even within patients with the same mutation, the location and type of MECP2 mutation...cell line repository (Link opens in a new window) Sampled - one of the world's largest biorepositories (Link...

... using CEPIA. Nat Commun. 2014 Jun 13;5:4153. Masamitsu Iino Calcium Red mitochondrial CEPIA calcium sensors...mitochondria. Sci Rep. 2020 Feb 18;10(1):2835. Masamitsu Iino Calcium Red calcium sensor FRCaMPi and SomaFRCaMPi...division. Science. 2010 Jun 4;328(5983):1295-7. Samuel Miller Chloride (Cl-) ClopHensor biosensor for ...

...webpages. These plasmids are described in Portales-Casamar et al., 2010 . List of Pleiades MiniPromoters MiniPromoter...promoter pEMS1488 intron-lacZ/NLS References Portales-Casamar, E., Swanson, D. J., Liu, L., de Leeuw, C. N., ...

...will also include virus-associated DNA, which is a sample of the purified DNA from the original plasmid that...

...libraries are a set of plasmids all built with the same backbone and only differing in a small region. Click...

...sequence: Up to two guides can be expressed from the same plasmid by utilizing one of the dual guide shuttle...

...label and detect multiple injection sites in the same tissue, as well as barcoding with specific enhancers...

...assembly, even as more parts are added. Therefore, the same reaction which ligates a promoter into an empty ...

...permitting selective simultaneous labeling in a sample. Please see the note below for information on substrates...