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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 573 results for: Cit

Showing: 381 - 400 of 573 results

  1. Chemogenetics Guide

    Type
    Guide
    ...ligand-gated ion channels (LGICs) that can either excite or inhibit neuronal signaling. PSAM-based LGICs...generates light that activates the opsin. The opsin may excite or inhibit the neurons expressing the LMO, depending...promoters in chemogenetics plasmids Promoter Cell Specificity hSyn1, CaMKIIa Neurons GFAP Glia CD68 Microglia...tissue, and this must be considered. For tissue specificity of AAV serotypes, see our AAV guide . FLEx Vectors...

  2. Gamma-Retroviral Vector Guide

    Type
    Guide
    ...stable long-term expression in a host and low immunogenicity. This guide contains many viral vector-specific...shRNA of interest flanked by LTRs; ~8 kb packaging capacity Packaging plasmid — contains packaging genes gag...glycoproteins of HIV generates a retroviral vector with specificity of infection for CD4-expressing cells. Proceedings...and the eventual cause of serious diseases. Immunogenicity The ability of a molecule or substance to induce...

  5. Reflections and Looking Ahead

    Type
    Blog Post
    ...boundaries of discovery. As I look ahead, I am excited to continue to grow and innovate with your help...

  6. Editor's Choice, September 2016

    Type
    Blog Post
    ...infect bacteria and that can do so with exquisite specificity (check out our interview with Michael Koeris ...

  7. Editor's Choice, August 2016

    Type
    Blog Post
    ...sequences specified by gRNAs. Caveats, potential specificity issues, and other means of generating mutations...

  12. Plan Your Experiment

    Type
    Guide
    ...High-fidelity Cas enzymes increase specificity Dual-nickase approach increases specificity but is less efficient Each...be able to completely avoid them. To increase specificity, consider using an engineered Cas enzyme with...use in the lab, but AAVs exhibits the lowest immunogenicity and are one of the least toxic methods for ...
Showing: 381 - 400 of 573 results