We narrowed to 568 results for: PAC;

1. CRISPR Protocol for Genomic Deletions in Mammalian Cell Lines [Video]

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   Blog Post

   ...deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system...

2. "What Makes a Good Mentor?" and 6 More FAQs About Science Mentoring

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   Blog Post

   ... how to be a great Mentor.    Check Out Angela Depace's Talk on "Precision and Plasticity in Mentoring...

3. mTOR Pathway

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   Collection

   ... survival and cytoskeletal organization. Cancer Impact Enhanced signaling through either mTORC1 or mTORC2...

4. CRISPR Plasmids - Prime Edit

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   Collection

   ...with a typical gRNA, the pegRNA is designed with a spacer that binds to a specific genomic DNA locus and ...

5. Distribution to Industry

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   Collection

   ...Proteins (SLCs) from the RESOLUTE collection AAV Packaging from Addgene Parkinson's Research from The Michael...

6. 2023 and 2024: Reflections and Looking Ahead

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   Blog Post

   ...ll be celebrating with stories of innovation and impact made possible by the sharing of tools for research...

7. pSiM24: Simplifying Plant Genetic Engineering

   Type

   Blog Post

   ..., smaller binary vectors with a larger cloning capacity would be very useful: enter pSIM24! To build a...

8. Celebrating Outstanding CRISPR/Cas9 Achievements at the Dr. Paul Janssen Award Dinner

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   Blog Post

   ...speechless (the club of people who have been in space is pretty small). Therefore, I was delighted to ...

9. 9 Tips to Achieve Success in Academia

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   Blog Post

   .... “There are many ways to have a large positive impact in society. We need much, much more science and...

10. CRISPR 101: Cas9 Nickase Design and Homology Directed Repair

    Type

    Blog Post

    ...: Use a PAM-out configuration Optimize your spacing D10A: nick sites separated by 37-68 bp H840A: ...

11. Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight

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    Blog Post

    ...and offers a high degree of control over time and space. Zebrafish have become a popular model organism ...

12. Some Like it Hot: Thermostable GeoCas9

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    Blog Post

    ... AA PAM Sequence NGG CRAA (R = A or G) Spacer Length 20 nt 22 nt Temperature Range for Optimal...

13. Embracing Serendipity: A Crucial Element in the PhD Journey

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    Blog Post

    ...your academic journey, remember to leave a little space for the unexpected — it might just be the key to...

14. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

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    Blog Post

    ...Targeting Further restricted to illuminated region Impacts all cells expressing receptors Invasiveness Mice...

15. Antibodies 101: Fc Effector Functions

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    Blog Post

    ...bind. We also know that changing the Fc domain can impact an antibody's binding affinity (Janda et al., 2016...

16. Cellosaurus: A Cell Line Information Database

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    Blog Post

    ...production, SARS-CoV-2 research, or adenovirus packaging cell lines dataset collections.  Depending on ...

17. Early Career Researcher Toolbox: Free Online Molecular Biology Tools

    Type

    Blog Post

    ...Removes non-DNA characters, such as numbers and blank spaces, from the text of a DNA sequence, making it ready...

18. CASTing Off for New Shores in Human Genome Editing

    Type

    Blog Post

    ...power of CRISPR combined with the large sequence capacity of transposons open whole new worlds to explore...

19. New CRISPR Web Resources and #12DaysofCRISPR Recap

    Type

    Blog Post

    ...Targeting Specificity with eSpCas9, SpCas9-HF1, & HypaCas9 Day 10: Transcriptional regulation: Truncated ...

20. Tips for Improving Your Next Manuscript

    Type

    Blog Post

    ... then the data produced isn’t likely to have an impact because it will be difficult or (more likely) impossible...