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We narrowed to 897 results for: TRI

Showing: 401 - 420 of 897 results
  1. With Our New Viral Service, We're Taking CRISPR Further!

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    Blog Post
    ... research community. At Addgene, we’ve helped distribute many of these technologies in plasmid form and...libraries. Please note, the pooled libraries we distribute in lentivirus format only deliver gRNA and therefore...like to thank all those who are allowing us to distribute their CRISPR tools as ready-to-use virus and,...
  2. 7 Tips to Secure a STEAM Internship This Summer

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    Blog Post
    ...This blog post was contributed by guest bloggers Roodolph (Roo) P. St Pierre and Rose C. St Pierre, founders...cannot offer. Furthermore, companies across most industries tend to hire their former interns to fill entry-level... of internships as a result of the necessary restrictions on close personal contacts. However, that should...
  3. A Practical Approach to Choosing the B(right)est Fluorescent Protein

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    Blog Post
    ...This post was contributed by guest bloggers Joachim Goedhart and Marieke Mastop from the Section of Molecular...sample. Practical brightness A protein with a high intrinsic brightness that does not fold well or cannot be...explanation of the assay is depicted in figure 1. The strict correlation between the fluorescent protein of ...
  4. Enabling Precision Functional Genomics with the Target Accelerator Plasmid Collection

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    Blog Post
    ... This post was contributed  by Jesse S. Boehm, the Associate Director of the Cancer Program at the Broad...works. But, those darn cancers have revealed many tricks up their sleeves and most patients still don’t ...or PolyPhen to approach this challenge, using attributes of cancer variants such as evolutionary conservation...
  5. Top Requested Lentivirus and AAV of 2016

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    Blog Post
    ...These viruses have been distributed in over 200 packages to more than 20 countries. With this initial success...in transgenic animals, where cre expression is restricted to a particular cell type. The human synapsin...
  6. Antibodies 101: Buffers, Storage, and Conjugates

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    Blog Post
    ...your antibody.  At some point in your long and illustrious lab career, you will likely accidentally leave...Brightness Chart. Boston University Flow Core. Retrieved January 31, 2022, from https://www.bu.edu/flow-cytometry...overlap. Syracuse University Flow Core Facility. Retrieved January 31, 2022, from https://flowcore.syr.edu...
  7. Viral Vectors 101: Inverted Terminal Repeats

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    Blog Post
    ...with biorender.com. ITR structure  WT ITRs are symmetrical 145-nucleotide sequences that flank the ends ...identification of non-dominant ITR sequences.  Restriction digests with the enzymes SmaI and SrfI can also...deletions and point mutations will go undetected by restriction digest methods.    Resources and references...
  8. Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur

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    Blog Post
    ... a biotech startup company? Would you like to contribute advice on how to effectively raise money and/... Capital in Biotech  - Posted on Forbes.com, contributed by Bruce Booth How to Find a Job in Biotech and...the Biotech Business - Posted on Nature.com, contributed by Julia Phillips and Fiona Beckman Acknowledgments...
  9. Channelrhodopsins with improved light sensitivity for minimally-invasive optogenetics

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    Blog Post
    ...real-time inside a mouse’s brain.  But the brain is a tricky organ to access, which often forces scientists ...electrophysiology, a technique that’s used to measure electric current of ion channels in living cells. Multiple...-stimulate” their VTA dopaminergic neurons by triggering a burst of light that could activate ChRger2 ...
  10. The Breast Cancer Microenvironment: A Tumor’s Backstage Team

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    Blog Post
    ...This post was contributed by Bárbara Pinho, a science communicator at the Portuguese science museum "...interleukin-6 (Witkiewicz et al., 2009) which contribute to the development and spread of cancer cells... scientists began focusing on the extracellular matrix and fibroblasts. With each cell mechanism discovered...
  11. Human Germline Editing Using CRISPR

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    Blog Post
    ...off-target effects attributable to CRISPR editing. Conclusions & implications One striking feature of this...especially in the case of older mothers, for whom egg retrieval often results in fewer eggs. However, the potentially...
  12. The time and cost required to make a plasmid

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    Blog Post
    ...plasmid, excluding any restriction enzymes or vector purchases (Table 1). Restriction enzymes and vector ...work done previously, borrow small aliquots of restriction enzymes for one-off projects, or even save yourself...
  13. The Future of Research Symposium Boston 2015

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    Blog Post
    ... held from 22-24 October. This blog has been contributed by guest blogger and Future of Research Symposium...the academic labour market. Her many notable contributions in this area include publishing the book ‘How...How Economics Shapes Science’ and contributing to the NIH’s Biomedical Research Workforce Working Group...
  14. Working with Nuclear Receptors

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    Blog Post
    ...This post was contributed by Neil J. McKenna and Bert W. O’Malley. Survival of all organisms depends ...organs, which then return information such as nutritional status. Within the animal kingdom, this information...300 different coactivator proteins individually contribute to cell regulation in a coherent manner. Because...
  15. Synthetic promoter AAVs for cell-type specific expression in retinal cells

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    Blog Post
    ...Applications for synthetic promoter AAVs Besides restricting AAV transgene expression to particular cell types...types, pairs of synthetic promoter can be used to restrict expression to a single cell type based on the ...cell-type specific promoters could be an easier way to restrict expression of a gene interest in an animal model...
  16. Early Career Researcher Toolbox: Finding Relevant Papers

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    Blog Post
    ...Scholar library. You can add hashtags to library entries, which can help you organize and search for papers...number of times a paper is shared online, or its altmetric score, is also displayed in your feed. By clicking...us know if you if you have any favorite tips and tricks for navigating the always growing sea of scientific...
Showing: 401 - 420 of 897 results