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We narrowed to 1,076 results for: TOR

Showing: 621 - 640 of 1076 results

  1. Top Requested Plasmid of 2017 - pMD2.G

    Type
    Blog Post
    ...2016 were CRISPR plasmids), but so are lentiviral vectors, many of which are used to deliver Cas9 and other....G from Didier Trono’s lab! Lentivirus envelope vector pMD2.G This plasmid has been requested nearly 6,000... our Viral Production Process Find other Viral Vectors ...

  2. Tips for Working in Industry & Success in Management: Interview with Crystal Shih

    Type
    Blog Post
    ...Crystal Shih is an Investigator III at Novartis, a multinational pharmaceutical company based in Switzerland...'ve helped her at Novartis. The importance of mentorship in developing career skills. Outro Many thanks...Addgene Find more management resources in our Mentoring for Scientists Series Learn about Turning Your...

  3. Addgene Stands with the Scientific Community

    Type
    Blog Post
    ...resources: Preserving scientific assets: We hold a repository of valuable research materials that might otherwise...continue to offer high-quality DNA sequencing, viral vector preparations, and antibody production that labs...continue.  Moving Forward Together Throughout history, the scientific community has demonstrated remarkable...

  4. A Scientist's Guide to Ebola

    Type
    Blog Post
    ...the virus itself that kills you, but the cytokine storm it ultimately sets off.  The virus works its way...cells and turn the cell into a veritable virus factory.  Their findings were reported in the Journal of...and the target of neutralizing antibodies and inhibitors of attachment and fusion. Recommended Reading...

  5. How Do I Place an Addgene Order Using a PO Number?

    Type
    Blog Post
    ...'Regan Ordering jeans online from your favorite store is easy. Ordering genes on plasmids online is a ...nonprofit, Addgene does not own the material in our repository. We distribute it on behalf of depositing institutions...full of information about how to deposit plasmids, store your plasmids or viral items, technical support,...

  6. Addgene's Website Update

    Type
    Blog Post
    ...two options: “Search Repository” and “Deposit Materials”. The “Search Repository” function is our same...section: Tools of the Day. Our plasmid and viral vector of the day have a fresh new look and a fresh new...

  7. Our Most Popular Blog Posts from 2019

    Type
    Blog Post
    ...Anti-CRISPR, 2in1 Cloning, Fluorescent Voltage Indicators, and Photoswitchable Proteins by Cary Valley,...Academic Job Interview by Erik Snapp Addgene depositor and guest blogger Erik Snapp breaks down how to... blog posts Resources at Addgene Browse the repository Find educational resources at Addgene Search ...

  8. Top 10 Open Science Developments of 2013

    Type
    Blog Post
    ..., even when all kinds of other factors, including journal impact factor, study topic, and the corresponding...preference to journal access granted via a public repository or authors’ own web sites. 9)      The year 2013...

  9. A new platform for fast functional characterization of potentially cancerous mutations

    Type
    Blog Post
    ...MCF10A cellular models. Ba/F3 and MCF10A are growth factor dependent cell lines and any mutations that that...advantages will be revealed in the absence of growth factor. The team assigned the mutations to functional ...significantly increased cell viability, and these “activators” may be the direct drivers of tumor formation...

  10. 9 Tips to Achieve Success in Academia

    Type
    Blog Post
    ..., and young Principal Investigators (PIs). We've interviewed Addgene depositors who are at various stages...different ways to succeed – as loner or gregarious;  dictator or laissez-faire; theory or practice; business-like...

  11. Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight

    Type
    Blog Post
    ...neurons that trigger the CPG (central pattern generator) (Wyart et al., 2009). The CPG is a neural circuit... involved in locomotion that generates periodic motor commands for rhythmic movements like spontaneous...optogenetics blog posts Read blog posts about viral vectors Subscribe to the Addgene blog Resources on Addgene.org...

  13. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

    Type
    Blog Post
    ...individuals through stock or investor pay outs. Addgene has no investors or stock. All of our proceeds...proceeds go into running the repository and serving scientists better. That includes keeping fees as low as ...

  14. Fluorescent Proteins 101: Fluorescent Biosensors

    Type
    Blog Post
    ...biological sensors’) are biological tools that monitor a process or detect a given molecule. The sensor...in. Depending on the process you would like to monitor, there may be multiple steps you could examine,...biosensors. These constructs are often used to monitor enzymatic activity or phosphorylation over time...

  15. Using Ultrasound to Image Bacteria in vivo: Acoustic Reporter Genes

    Type
    Blog Post
    ...biodistribution therefore introduce additional confounding factors when attempting to interpret signals from these...collapse E. coli re-express arg1 gas vesicles and restore their ultrasound signal. Using acoustic reporter...years to clinically treat enteric infection and inflammatory bowel conditions. In these experiments, arg1...

  17. We're Updating Our Hold for Publication Policy

    Type
    Blog Post
    ...original policy was straightforward, but cumbersome: depositors had to email us with permission to release their... are left in the hold status and reach out to depositors about them, but we all know how easy it is to...your work. Plus, it’s costly for us to process and store materials that aren’t distributed or for our teams...

  18. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    ...affiliated TniQ protein recruits transposition cofactors. The transposon proteins integrate a payload sequence... Figure 1: Mechanism of CAST systems. A Cas effector (Cascade in Type I systems; Cas12k in Type V-K...Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase. Science...

  19. An Addgene Summer Internship

    Type
    Blog Post
    ... gene in a pLenti vector backbone. During those five weeks, I worked with my mentors, Katherine, Amrita...exchanged contact with Amy C., Addgene’s intern coordinator shortly after hearing her talk about Addgene’...

  20. Build Your CRISPR Vocabulary

    Type
    Blog Post
    ...used to target complementary DNA sequences. In laboratory settings, an sgRNA includes the crRNA and tracrRNA...array: The section of the bacterial chromosome that stores a genetic record of previously encountered foreign...itself, simplifying the CRISPR-Cas9 system for laboratory applications. At Addgene, we sometimes refer ...
Showing: 621 - 640 of 1076 results