We narrowed to 929 results for: INA

1. Your Top Requested Plasmid in 2015!

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   ...2015 was... lentiCRISPR V2   LentiCRISPR v2 originates from Feng Zhang’s lab at the Broad Institute ...cells, deciphering the mechanism of matrix metalloproteinase-9 secretion, and identifying lysine methyltransferase...

2. CRISPR-Cas14: a family of small DNA-targeting enzymes enabling high-fidelity SNP genotyping

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   ...cleavage, the authors showed that Cas14 could indiscriminately cleave ssDNA in trans like Cas13 and Cas12...adding Cas14 to the mix, you get the ultimate combination enabling the detection of RNA, dsDNA, and now...

3. Q&A With Julie Cicalese, the Newest Member of the Addgene Board of Directors

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   ...forward. Sooner or later enough people will be vaccinated and we’ll have some herd immunity, which raises...Giving think tank event where we brought a multidisciplinary group of scientists together to draft a research...

4. Science Communication Snapshot: DayCon 2015

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   ... timely scientific topics, as well as archived seminar presentations. One of SITN's newest initiatives...The afternoon program mixed things up with a combination of shorter, more narrowly focused lectures, interactive...

5. Designer PUF Proteins for Any RNA Target

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   ...of the high fidelity version (despite what the original paper says). In their hands, BsaI-HF has produced...they hope others will do the same. “This isn’t the final version,” she said. “If we learn how to make the...

6. Save Time and Money by Making Your Own Competent Cells

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   ...adding plasmid) to make sure you don’t have contamination.  Also conduct a positive control (test a ... Melina Fan...

7. Editor's Choice, August 2016

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   ...technique uses catalytically inactive CRISPR endonuclease (dCas9) fused to a deaminase to make the transitions...

8. Modulate the Activity of 17 Signaling Pathways with One Kit!

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   ..., in collaboration with “cloning guru” Kathleen Ottina and David Sabatini at the Whitehead Institute and... over-expressed, constitutively activated or inactivated the pathway. “The idea is that if you introduce...

9. X-CHIME: Context Dependent Germline Knockout in Immune Cells

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   ...different cell types, at different times, and in combination with different genes. Having CRISPR systems for...G., & Sharpe, A. H. (2024). X-CHIME enables combinatorial, inducible, lineage-specific and sequential ...

10. Searchable and Sortable gRNAs for Your Next CRISPR Experiment

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    ...that you confirm the details and final experimental outcome in the original publication. As you develop and...

11. Spurred by COVID-19, Addgene Bridges Plasmid Sharing Between Academia and Industry

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    ... more broadly to accelerate COVID-19 research: Sinai Health System                                     ...Essen                      University of North Carolina at Chapel Hill University of Illinois Chicago                     ...

12. Addgene is Expanding Our Viral Vector Service!

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    ...or in vivo testing. We recommend you check the original paper of your AAV plasmid of choice for more information...be available through our distributor partners in China, Brazil, Japan, Korea, Mexico, and India. Once the...

13. Increasing Your Work's Visibility with Addgene: Citation, Search, and Collections

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    ...Addgene ID number as well as the reference for its original publication. To help facilitate this process, ...also increases the visibility of both you and the original depositor. Our citations feature makes it so that...

14. A Better Way to Get Customer Support: The Help Center

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    ...philosophy Customer service can be a hassle. You finally make it through a 20-step phone tree, only to be... be left on hold for an hour. When you finally speak to a human being, you may not even get a solution...

15. Mapping the 4D nucleome with CRISPR/Cas9

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    ...are thus limited by its lower resolution. The combination of this method with superresolution microscopy... is so high, cells may be imaged under lower illumination settings, lowering photobleaching and phototoxicity...

16. 9 Tips to Achieve Success in Academia

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    ...than intensely competitive. Be curious and interdisciplinary.   3. “There are many different ways to succeed...science, especially if the conference is a big multidisciplinary one.” Cepko strongly emphasizes that people...

17. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

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    ... ligand from the Bryan Roth lab and Takafumi Minamimoto’s lab known as deschloroclozapine (DCZ) has been...activation Targeting Further restricted to illuminated region Impacts all cells expressing receptors...

18. Plasmids 101: What is a plasmid?

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    ...Originally published Jan. 14, 2014 and updated Apr. 14, 2020. Any newcomer who joins a molecular biology...types the gene is expressed in and amount of recombinant protein obtained. Selectable Marker The antibiotic...

19. ReFigure: Save Scientific Figures into Dashboards and Share Your Insights

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    ...in “negative data” often dominate the early years of a project. Dissemination of the knowledge gained ...

20. Hot Plasmids and Viral Preps - July 2021

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    ...controllable gene knockouts, and inducible gene inactivation or activation in an organoid model (Sun, et ...activity.  As SLs are also known to trigger seed germination of parasitic plants, this approach was also used...