We narrowed to 818 results for: MAL

1. Reagent Repositories Are Speeding up Science During the Pandemic

   Type

   Blog Post

   ... Subbarao K, Roberts A (2006) Is there an ideal animal model for SARS? Trends in Microbiology 14:299–303...

2. Scientists Map the SARS-CoV-2-Human Interaction Network

   Type

   Blog Post

   ...everything we can to help find a cure -- and quickly. Normally drug discovery is a process that would take years...

3. Using CRISPR/Cas9 to Edit Disease Out of the Genome

   Type

   Blog Post

   ...that CRISPR/Cas9 could be used to edit several autosomal-dominant mutations that have been connected to...

4. The Crispr Babies Saga Shows the Need for Action, Not More Delays

   Type

   Blog Post

   ...practice: computer simulations, in vitro research, animal models, and several stages of human clinical trials...

5. Addgene-Seeding Labs plasmid grant round 3: microbial drug resistance and biofilms, antidiabetic plant components, visualizing brain injury - and a glowing robot fish

   Type

   Blog Post

   ...strain. The sensor will be transported inside a small 3D printed robot that will “swim” in the river, ...

6. The Importance of High Titer for AAV Transductions

   Type

   Blog Post

   ...:  Versatile Viral Tool for Gene Expression in Mammals Additional Resources on Addgene.org Find Ready-to-Use...

7. Predicting Adverse Reactions to Monoclonal Antibody Drugs

   Type

   Blog Post

   ...of a middle ground between 2D assays and in vivo animal models. In these cases, they are designed to mimic...

8. FPbase: A new community-editable fluorescent protein database

   Type

   Blog Post

   ...interest (and we very much appreciate even those small contributions). Of course, no community-editable...

9. 5 Great Apps for Lab Life

   Type

   Blog Post

   ... Lastly, the Tm calculator helps you set up an optimal PCR depending on the primer sequence and the NEB...

10. R Bodies: Membrane-Rupturing Microscopic Tools

    Type

    Blog Post

    ...to find R body mutants that couldn’t extend at a normal pH and later realized that these mutations clustered...

11. Viral Vectors 101: Viral Vector Elements

    Type

    Blog Post

    ...viral vectors Of the many viruses out there, only a small subset are commonly used as tools in the lab. We...

12. GCE4All: Making Genetic Code Expansion Accessible

    Type

    Blog Post

    ...paper was published, followed soon by GCE done in mammalian cells (Shandell et al., 2021).   How it works...

13. Viral Vectors 101: Viral Applications

    Type

    Blog Post

    ... A Versatile Viral tool for Gene Expression in Mammals Listen to Connie Cepko Discuss Gene Therapy with...

14. Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies

    Type

    Blog Post

    ...your docking site is located). This amounts to a small difference of two or three weeks. 3. How would you...

15. Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer

    Type

    Blog Post

    ...starvation on cancer therapy. Findings in previous animal studies suggested that fasting has a positive effect...

16. Multiplex Genome Editing with CRISPR-Cpf1

    Type

    Blog Post

    ...bulk from crRNA expression plasmids resulting in smaller, more streamlined vectors which are easier to use...

17. Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification

    Type

    Blog Post

    ...light is in an open conformation.  Nanobodies are a small (~15 kDa), single monomeric variable heavy chain...

18. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

    Type

    Blog Post

    ... genes for noninvasive imaging of microbes in mammalian hosts Article contributed by Lukas Morgan  Listen...

19. New and Upcoming Viral Vectors - May 2020

    Type

    Blog Post

    ...experiments. To this end, we offer control AAV in smaller aliquots of 20ul for serotype testing to help you...

20. The Many Reasons for Irreproducible Research- and a Vaccine to Eradicate It

    Type

    Blog Post

    ... the problems above: unclear methods, QRPs, and small samples, then when replications do not come out ...