We narrowed to 810 results for: Mal

... also false negatives: These are rare, but if a small fragment is inserted in-frame, read-through can ...

... could typically achieve 90-99% knockdown with minimal off-target effects. The system also enabled them...

...one can introduce changes into the genomes of mammalian or other cells. TALENs are engineered proteins...

...great gene therapy delivery mechanism, but their small packaging capacity of 4-5 kb limits the delivery...

... faster presentation with more information than normal. I had to learn to observe and adjust on the fly...

...better resolution as these immune complexes are smaller than a primary:secondaries:conjugates complex. ...

...survey found that many researchers feel they lack formal training in a variety of transferable skills. At...

...pooled library of mutant sensors expressed in a mammalian cell line engineered to be electrically excitable...

...further away. While constitutive promoters drove maximal gene expression near genomic origins of replication...

...” “material,” “item,” and “format” all received formal definitions in our lexicon. We created documents...

...expression of ion channels, despite having an otherwise normal genomic background, can even lead to the formation...

...to use or build on work done previously, borrow small aliquots of restriction enzymes for one-off projects...

...quantified for individual cells, and the number of 'normal' looking cells can be counted. This assay will ...

...should enable researchers to make precise edits in mammalian cells and may decrease worries about off target...

...increased number of fragments, or the ligation of very small/very large fragments, these problems can be overcome...

...references and sorting out what they mean is no small task. As a scientist, it is useful to make literature...

...plasmids in bacteria — has many points at which small errors can be introduced. Eventually, these errors...

...2024). Improving prime editing with an endogenous small RNA-binding protein. Nature, 628(8008), 639–647....

...between strand 10 and 11 to yield large (1–10) and small (11) fragments. In several cases an FP(1–10) fragment...

...is best used for detecting antigens that are too small to be captured between two antibodies in a sandwich...