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Learn about some of the factors you should take into consideration when choosing the appropriate AAV for your next experiment.

Browse Addgene's collection of plasmids for the generation and study of stem cells, from iPSC generation to directed differentiation.

An introduction to gene, enhancer, and promoter trapping. Relevant examples of each along with pros and cons of each system.

Find some tips and tricks for using CRISPR for gene editing.

The COVID-19 pandemic makes open science more important than ever. Read about how Addgene is weathering COVID-19 with support from the scientific community.

Learn about different strategies used to generate plasmids for multiplex gRNA expression and how to use them in various organisms.

Photoactivatable fluorescent proteins can be switched on (and sometimes off) enabling a variety of techniques and applications.

A review of K. phaffii as a model organism and its relevant applications for biotech to basic research.

Seeding Labs and Addgene collaborate to provide scientific resources, equipment, and plasmids to researchers in resource-limited settings. Read more to learn about the recipients of the Addgene-Seeding Labs plasmid grant this year.

Addgene's Advisory Board helps steer and promote Addgene in its goal of sharing science. We welcome CRISPR expert, John Doench, to the Advisory Board.

We provide high quality AAV preps from select plasmids in the repository. Browse our AAV collection of site specific recombinases.

Addgene's guide to using CRISPR plasmids in your lab, from knockouts to pooled library screening.

How do we know if a therapeutic antibody is a promising clinical prospect? In vivo and in silico methods can help us decide!

Learn about SF-iGluSnFr, an updated glutamate biosensor from Loren Looger's lab.

Repositories provide fast access to wet lab research materials during COVID-19 such as cell lines, plasmids, and mouse strains.

Check out how you can use the top lentivirus and AAV from 2016 in your own research.

Overview of polycistronic glycine tRNA-gRNA (PTG) multiplexing gRNA cassettes, with comparisons to Pol III and Cys4 gRNA cassettes.

Addgene's interviews Chris Voigt of MIT about the intersection of CRISPR and synthetic biology and his new work building circuits with CRISPRs.

Learn more about non-homologous end joining (NHEJ) and how it relates to genome engineering technologies such as CRISPR/Cas9.

Addgene's plasmids for the mTOR pathway. enhanced signaling of mTOR, a key metabolic regulator, correlates with poor prognosis in many cancers.