We narrowed to 112 results for: NOG;

... PMCID: PMC49604. 4. Independent control of immunoglobulin switch recombination at individual switch regions...

...blog post on CRISPR’s potential for correcting monogenetic diseases. Now, almost 10 years later, CRISPR’...

... Jiang F, Liu J-J, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA (2017) Disabling...

...doi.org/10.1016/j.neuron.2013.08.032.  Morita S, Noguchi H, Horii T et al. (2016) Targeted DNA demethylation...

...stem cells, and developing gene therapies for monogenic diseases. Additionally, retroviral vectors can...

...targeting Cas system that can be used in Drosophila melanogaster. Get the plasmids at Addgene The Cas Hybrid...

... than polyclonal antibodies because of their immunoglobin component that can be produced in large “copies...

..., X. laevis (frog), D. rerio (zebrafish), D. melanogaster (fly), C. elegans (nematode), S. cerevisiae ...

... for in vivo gene delivery due to their low immunogenicity and range of serotypes allowing preferential...

...used when injecting a cell suspension to create xenograft models. Restraint: back scruffing or mechanical...

...For larger libraries that require hundreds of nanograms of DNA, you will likely need to perform several...

...with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell 46:291–300...

...Toolbox for Genome Editing in Cultured Drosophila melanogaster Cells.” G3 (Bethesda) 6(6) (2016):1777-85. PubMed...

...Replacement by Compound Autosomes in Drosophila melanogaster. Genetics 74, 461–475 (1973). PubMed. More ...

... in vivo studies, little is known about the immunogenicity and stability of the Cas9 protein in the host...

...reconstitute the gene of interest, reducing the immunogenicity typically associated with viral vector-based...

...Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak ...

... brain because of its low cytotoxicity, low immunogenicity, and the long-term expression of AAV delivered...

...impacts of this disease.  As a non-degenerative, monogenic disease that has shown reversibility of symptoms...

...immunoresponses. Nucleotides, in general, are far less immunogenic than proteins. Assays that require recognition...