We narrowed to 971 results for: LARS

1. Antibodies 101: Chimeric Antibodies

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   ...to do?  If you’ve ever found yourself facing a similar problem, then isotype converted, or chimeric, antibodies...

2. New Viral Vectors - Winter 2025

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   ... pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato AAV8 Molecular tool Massimo Scanziani New viral prep pAAV_hSyn1...

3. Another Pathway into Cells: iTOP

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   ...feasible for many labs.  References Efficient Intracellular Delivery of Native Proteins. D'Astolfo DS, Pagliero...

4. Interview: Ed Boyden on Optogenetics, Neuroscience, and the Future of Neuroengineering

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   ...plasmids to Addgene over the years, many of them very popular. Why has it been so important to you to distribute...

5. Plasmids 101: Gram Negative and Positive Bacteria

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   ...dehydrates the peptidoglycan layer, trapping the large dye complex created by the interaction of CV+ and...

6. Revamp Your Lab Meetings With Creative Virtual Collaboration

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   ...et al., 2018): “Science is increasingly done in large teams, making it more likely that papers will be...

7. New and Upcoming Viral Vectors - September 2019

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   ...and is useful for imaging signaling activity in large populations of densely-labeled neurons because background...

8. The Crispr Babies Saga Shows the Need for Action, Not More Delays

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   ...mitochondrial DNA disorders.” This document is about the popular technique incorrectly known as “three-parent babies...

9. Photosensitizer Induced Cell Ablation with FAP-TAP MG-2I-dL5**

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   ...or in cell nuclei. The two photosensitizers had similar rates of off-target damage to neighboring cells...

10. Science Career Options

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    ... or be on your feet constantly in a lab? Will regular travel be required or will you stay in one location...

11. The MTA at Addgene

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    ...clearly communicated. And that’s where MTAs, and similar agreements, shine.  These types of agreements allow...

12. Optimizing Donor DNA for Enhanced CRISPR Genome Editing

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    ...rates of approximately 1%. This is by no means a large number, but it was attained without any of the error-prone...

13. Addgene Welcomes John Doench to the Advisory Board

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    ...making science easier and more transparent. That’s largely my job [at the Broad] too… to make science easier...

14. Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors

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    ...base editors (ABEs). How does this work? Through molecular biology teamwork. The guide RNA (gRNA) specifies...

15. AAV Q&A with Tim Miles

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    ...Would you recommend any liver specific capsid, particularly one that can target the epithelial cells in ...

16. Building and Validating Recombinant Antibodies: A Case Study

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    ...to generate these antibodies were based off of a large collection of mouse monoclonal antibodies (mAbs)...

17. Antibodies 101: Isotypes

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    ...which can initiate a cascade that helps attack extracellular pathogens.  Transportation of antibodies to ...

18. Screening for Successful Genome Editing with Digital PCR

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    ...University of Alberta. He is interested in everything molecular biology. Follow him on Twitter @AnotherLabRat....

19. CasPEDIA: A Functional Classification of Cas Enzymes

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    ...phylogenetic nomenclature and discover orthologs with similar properties (Makarova et al). CasPEDIA is an evolving...

20. GCE4All: Making Genetic Code Expansion Accessible

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    ...trickiness of using and optimizing GCE, led to a large toolbox filled with systems and ncAAs that were,...