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  1. Cultivating Community Science at BosLab

    Type
    Blog Post
    ...initiated a soil microbiome project. This project was inspired by previous city-wide genomic studies and our ...DIY bio If you’re not in the Boston area but are inspired to get involved, check out the local groups page...

  3. Four Factors that Differentiate the Stem Cell Field

    Type
    Blog Post
    ...Hideyuki Okano presented ground-breaking work on spinal cord injuries; Jessica Young shared research on..., a half-brother who is a quadriplegic due to a spinal cord injury, and numerous family friends who had...

  4. Viral Vectors 101: The AAV Retrograde Serotype

    Type
    Blog Post
    ...transduction in catecholamine pathways from the spinal cord (Wang, 2018, Metcalfe, 2022) and substantia...that are physically blocked, such as those in the spinal cord. Now that you understand this new tool, go...

  9. Viral Vectors 101: Virus Safety

    Type
    Blog Post
    ..., some adenovirus strains are known to cause respiratory diseases in humans, earning this virus a BSL-... can be used for extra security. Finally, when spinning down lentivirus, you’ll need to use centrifuge...

  10. Hot Plasmids February 2024

    Type
    Blog Post
    ...for your next experiments, they will also likely inspire further-improved versions. Thanks to Christophe...Leterrier, whose FocalPlanes piece on mStayGold inspired and informed this section.  Find mStayGold plasmids...

  12. Experimenting in an Open Source lab: from CRISPR to Cats

    Type
    Blog Post
    ...the picture had a broken controller and would not spin. It was going to cost far more than it was worth...microcontroller and a motor controller and made it spin again!  We’ve also learned to be resourceful and...

  14. Viral Vectors 101: Producing Your rAAV

    Type
    Blog Post
    ...) using a high-speed ultracentrifuge. During the spin, the virions will form a band due to their high ... https://doi.org/10.1089/hum.2010.107 Zen, Z., Espinoza, Y., Bleu, T., Sommer, J. M., & Wright, J. F. ...

  18. AAVs in Retinal Gene Therapy

    Type
    Blog Post
    ...follow in the footsteps of Luxturna™. However, despite promising results in preclinical studies some potential...diseases such as hemophilia, muscular dystrophy, spinal muscular atrophy, neurodegenerative diseases and...

  19. Getting to Know Expansion Microscopy

    Type
    Blog Post
    ...now available. In this post, we’ll review the inspiration behind ExM, how it works, and some of the limitations...improve label density (Mikhaylova, et al. 2015).  Despite these limitations, ExM is a valuable tool, especially...
Showing: 81 - 100 of 296 results