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Right variable region, but wrong constant? Chimeric antibodies may be the answer!

Viral genome sequencing is a high-throughput method for determining AAV transgene identity and confirming the serotype.

TOPO cloning is a restriction enzyme and ligase free cloning method. Learn how TOPO works in this post.

Learn about the differences in virus production between insect cells and mammalian cells.

Learn about the structure and life cycle of retroviruses to help understand how to use viral vectors tools in the lab.

Chromoproteins are a subset of the fluorescent protein family. They give strong color in visible light and can be used for molecular biology experiments.

Antibiotic resistant bacteria are a huge issue in the clinic - learn how CRISPR is being developed to fight against antibiotic resistant super bugs.

CRISPR plasmids for precisely editing DNA bases without inducing a DNA break.

Need help with the plasmid deposit process at Addgene? Consult this post for an in-depth walk through the entire process.

Plasmids from Addgene encoding SARS-CoV-2 spike protein variants can be used to study antibody neutralization escape.

Learn what the Gal4/UAS system is and how it can enable powerful experiments in Drosophila.

Want to show how often your plasmids are requested? Or where they're being shipped to? The depositor-developed Addgene Request dashboard can help!

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

Discover the history of Rett Syndrome research, the role of the MECP2 gene, and some of the latest breakthrough therapeutic approaches for Rett Syndrome.

Learn how a new episomal plasmid-based method can be used to efficiently reprogram blood cells to induced pluripotent stem cells

The Framework for In vivo T cell Screens (FITS) allows for in vivo CRISPR screening in T cells. Learn more about FITS in our blog post.

Learn how you can use the Broad Target Accelerator Plasmid Collections from to help enable precision cancer medicine research.

New CRISPR pooled libraries, such as SAM, CRISPRa, and CRISPRi, offer new ways to do genome-wide functional screens.

Addgene has a new brand identity! This post describes the design decisions that went into our new logo, style, introductory video, and our mascot, Blugene.

This post highlights some of the tools Addgene makes available to industry scientists.