pCXLE toolkit: Efficient episomal plasmid-based method to reprogram peripheral blood cells to iPSCs
Type
Blog Post
Published
Dec. 14, 2017, 2:08 p.m.
... ID#
Encodes
pCXLE-hSK
27078
SOX2 and KLF4
pCXLE-hUL
27080
L-MYC and LIN28
pCXLE-hOCT3/4-shp53-F...efficiency, an extra plasmid, pCXWB-EBNA-1 is used in the reprogramming cocktail. pCXWB-EBNA-1 lacks oriP and ...samples. All pCXLE vectors listed below in Table 1 are available at Addgene.
Table 1: List of pCXLE episomal...reprogramming.
Enhancing PBMC reprogramming efficiency: the pCXLE episomal vector toolkit
It has been shown previously... the reprogramming efficiency in PBMCs [7]. The pCXLE episomal vector system generated by the group is...other episomal plasmids. When used on PBMCs, the pCXLE episomal vector system increases the efficiency ...improvement from the previously reported efforts. The pCXLE episomal system thus provides a practical way to...