Viral Vectors 101: AAV Serotypes and Tissue Tropism
Type
Blog Post
Published
Jan. 16, 2025, 2:15 p.m.
...them to target particular cell types.
Figure 1: Diagram of AAV components. Created with BioRender.com...depends on your choice of promoter/enhancer.
Table 1: AAV capsids and receptors.
Capsid
Primary receptor...required)2
Human fibroblast growth factor receptor 1 (FGFR1)3
αVβ5 and α5β1 integrins3
Hepatocyte growth...structure of AAV2, so they are formally called rAAV2/1, rAAV2/2, and so on, although we often use abbreviated...utilizing various AAV serotypes. Scientific Reports, 15(1), 20927. https://doi.org/10.1038/s41598-025-05518-...-directed transduction. Nature Communications, 14(1), 3792. https://doi.org/10.1038/s41467-023-39554-7... and Transduction by Adeno-Associated Virus Types 1 and 6. Journal of Virology, 80(18), 9093–9103. https...