Exploring Applications of the Bioluminescent HiBiT Tag
Type
Blog Post
Published
Oct. 2, 2025, 1:15 p.m.
...-in HiBiT-tagged EGFR cells allowed researchers to track endogenous activity of EGFR, including dose-dependent...receptor dynamics at the cell surface.
Find HiBiT-EGFR and EGFR-HiBiT Fusion Vectors at Addgene!
Measuring messengers...apart. While the classic Green Fluorescent Protein (GFP) and other fluorescent proteins revolutionized live-cell...HiBiT to track epidermal growth factor receptor (EGFR), a transmembrane receptor tyrosine kinase essential... was the ability to track the internalization of EGFR in real time treatment with EGF. Due to the lack...signal, associated with endosomal localization of EGFR. This method offered kinetic, non-invasive monitoring... through its principal receptor tyrosine kinase VEGFR2 (also known as KDR), orchestrating blood-vessel...