Hot Plasmids: February 2026
Type
Blog Post
...expressing Lifeact fused to mScarlet3-S2, mScarlet3-M163H (mScarlet3-H), or mScarlet3. Reproduced from Ding ...this barrier. The Fu Lab designed mScarlet3-H (also known as mScarlet3-M163H), inspired by crystal structures...proteins in identical conditions.
Find mScarlet3-S2 and mScarlet3-H plasmids here!
Ding, Y., He, W., Wang...resulting in mScarlet3-S2 (M163H/M66Q; the "S" is for "stable") (Ding et al., 2026).
mScarlet3-S2 and mScarlet3...mScarlet3-H showed up to 29- and 15-fold higher photostability than mScarlet3, respectively. Although they...make up for it over the long term (Figure 1). mScarlet3-H was also stable under extreme conditions like... on to learn more about:
Highly photostable mScarlet3 variants
Addgene's own AAV2 and AAV5 packaging...