We narrowed to 330 results for: ARIA

... loop to produce SuperFi-Cas9, a high-fidelity variant that still retains high cleavage efficiency (Bravo...Components of CRISPR  xCas9: Engineering a CRISPR Variant with PAM Flexibility Cas9 vs the Other Cases Further...

...et al. A percentage is not listed because many variables (cell type, criteria used, etc.) can effect reprogramming...insertional mutagenesis and random integration creates variation between iPSC clones. Retroviruses are not considered...

... CRISPR and Wednesday will highlight some Cas9 variants. Next, we’ll look at various CRISPR applications...

...Hub What is a Virus (and a Viral Vector)?  AAV Variables that Matter...

...Hub What is a Virus (and a Viral Vector)?  AAV Variables that Matter...

...contain the antigen binding sites and are highly variable, allowing exquisite specificity. This characteristic...

...specificity of multiple wild-type and engineered variants of Cas nucleases. In doing so, they also created...

... in human cells. Thus, they engineered two CBE variants with mutations in the rat APOBEC1 that decreases...

...however nuclear translocation rates are another variable to consider when designing KTR experiments. Third...

... they’ve engineered SECURE adenine base editor variants using a protein-truncation strategy with reduced...

...results of Myriad's genetic tests for breast and ovarian cancer risk directly from customers. 6)      An...

...erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science 2013...

.... In particular, they’re focused on generating variants with improved affinity and dynamic range of both...

... other orthologs. Ma et al. tested their dCas9 variants using gRNAs specific for telomeric sequences and...

...Hub What is a Virus (and a Viral Vector)?  AAV Variables that Matter...

... is composed of identical repeat sequences and variable spacer sequences. The array is transcribed and...

... line knock-ins of patient mutations which are variants of unknown significance – mutations with unclear...

...in moderate thermophiles.  These evolved SpCas9 variants have improved activity on NAG PAMS and reduced...

...Tris-EDTA (TE), just Tris buffer, or some other variations. Does it make a difference? Short answer: yes...

...length of the truncated attP site. The three SPARC variants, based on the length of the attP site, allow for...