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We narrowed to 192 results for: pme i

Showing: 181 - 192 of 192 results
  1. Cancer and the Immune System: Deciphering the Relationship

    Type
    Blog Post
    Published
    March 14, 2017, 2:30 p.m.
    ... the major histocompatibility complex (MHC) class I proteins on their surfaces to avoid recognition by...tumors and cancer. The immune response to the development of tumors is a complicated and dynamic phenomenon... Equilibrium - In a process analogous to the development of drug resistance in bacteria, the tumor cells... onset of cancer. Similar patterns of cancer development are observed in autoimmune disorders. Chronic...autoimmune disorders is also known to precede cancer development, for example, inflammatory bowel disease is associated...in the various types of cancer will fuel the development of immunotherapeutics. There are still many important...
  2. Quick Guide to All Things Lentivirus

    Type
    Blog Post
    Published
    March 21, 2017, 2:30 p.m.
    ...effective for T cells transduction for instance. I hope you will find this information useful for your...sensors. Retroviral vector background Until the development of viral vectors, gene transfer into mammalian...was a disadvantage particularly for clinical development. In addition, MoMLV is inefficient at infecting...
  3. RNA Interference in Plant Biology: New Tools for an Old Favorite

    Type
    Blog Post
    Published
    Oct. 27, 2020, 1:15 p.m.
    ...direction and scope of the subsequent two. Consequently, I will focus on different approaches and considerations...Although all these steps are areas of active development, the first step necessarily dictates the direction...: a mechanism underlying genetic robustness. Development 147:dev186452 . https://doi.org/10.1242/dev.186452...
  4. When Fidelity Matters: A frank discussion about ligase fidelity

    Type
    Blog Post
    Published
    March 6, 2018, 1:49 p.m.
    ...PMC516055. 23. Pascal, John M., et al. "Human DNA ligase I completely encircles and partially unwinds nicked ...conditions, and formulations and has led to the development of the new HiFi Taq DNA Ligase. Using this method... PMID: 23142428. 17. Hamada, Mariko, et al. "Development of a ligase detection reaction/CGE method using...PMID: 23463388. 18. Hommatsu, Manami, et al. "Development of a PCR/LDR/flow-through hybridization assay...
  5. Exploring Applications of the Bioluminescent HiBiT Tag

    Type
    Blog Post
    Published
    Oct. 2, 2025, 1:15 p.m.
    ... ADAR1, which converts adenosine to inosine (A-to-I) within double-stranded RNA. They hypothesized that...move discoveries from the lab bench into drug development. HiBiT technology helps close this gap! Bridging...
  6. PiggyBac-ing Through the Genome Editing Field

    Type
    Blog Post
    Published
    May 31, 2016, 3:30 p.m.
    ...T. Dargitz, R. Wright, A. Khanna, F. H. Gage, and I. M. Verma, “Functional Gene Correction for Cystic ...efficient manner than ever before, thanks to the development of site-specific nucleases (CRISPR/Cas9, TALENs...
  7. Technologies Enabled by NanoLuc® Luciferase

    Type
    Blog Post
    Published
    Feb. 8, 2018, 12:17 p.m.
    ...ever since there were plasmids to share. Back when I was in the lab, if you read a paper and saw an interesting...Hooper, PhD, has also worked with R&D for product development and now specializes in supporting Promega cellular...
  8. Viral Vectors 101: AAV Variables That Matter

    Type
    Blog Post
    Published
    June 1, 2023, 1:15 p.m.
    ...gang, Mesik, L., Liang, F., Tao, H. W., & Zhang, L. I. (2017). AAV-Mediated Anterograde Transsynaptic Tagging...vivo. Molecular Therapy - Methods & Clinical Development, 3, 16062. https://doi.org/10.1038/mtm.2016.62...
  9. Antibodies 101: Introduction to Antibodies

    Type
    Blog Post
    Published
    Jan. 19, 2021, 2:15 p.m.
    ...that antibodies can be used for a lot of purposes! I hope you appreciate how many types of antibodies are...reagent sharing platform for antibodies, the Developmental Studies Hybridoma Bank Learn more about nanobodies...
  10. Optogenetics + CRISPR, Using Light to Control Genome Editing

    Type
    Blog Post
    Published
    Sept. 3, 2020, 12:15 p.m.
    .../doi.org/10.1038/nchembio.1753 Richter F, Fonfara I, Bouazza B, Schumacher CH, Bratovič M, Charpentier...Dalvie NS, Panda A, Fleming HE, Bhatia SN (2016) Development of Light-Activated CRISPR Using Guide RNAs with...
  11. Technical Design of a Western Blot

    Type
    Blog Post
    Published
    Aug. 22, 2024, 1:15 p.m.
    ...., Podrebarac, D. M., Greenough, W. T., & Weiler, I. J. (2008). The use of total protein stains as loading...that each type of transfer requires different equipment. Wet transfers can be done in an insert in your...
Showing: 181 - 192 of 192 results