We narrowed to 251 results for: SPI;

1. Rett Syndrome: A History of Research and Therapeutic Outlooks

   Type

   Blog Post

   Published

   Nov. 19, 2020, 2:15 p.m.

   ...exhibit slow head growth, develop seizures, cardio-respiratory dysfunction, distinctive hand movements, and ...

2. Overcoming the AAV Size Limitation for CRISPR Delivery

   Type

   Blog Post

   Published

   Sept. 16, 2020, 1 p.m.

   ...019-0501-5  Liu J-J, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington...

3. Four Base Editing Reporters to Monitor and Enrich Editing in Real-time

   Type

   Blog Post

   Published

   July 7, 2020, 1:15 p.m.

   ...populations. To develop this method the lab was inspired by work that used an integrated GFP reporter that...

4. Plasmids 101: Plasmid Incompatibility

   Type

   Blog Post

   Published

   March 31, 2020, 1:15 p.m.

   ...References  del Solar G, Giraldo R, Ruiz-Echevarría MJ, Espinosa M, Díaz-Orejas R (1998) Replication and Control...

5. Antibodies 101: Immunoprecipitation

   Type

   Blog Post

   Published

   Dec. 7, 2021, 2:15 p.m.

   ... slightly higher, than those of agarose beads, despite the size difference. Magnetic beads are particularly...

6. Twenty Years of Sharing: Expanding Accessibility

   Type

   Blog Post

   Published

   Nov. 21, 2024, 10:47 p.m.

   ...shipping. However, there were issues that persisted despite our best efforts. With a little over half of our...

7. Plasmids 101: Stringent Regulation of Replication

   Type

   Blog Post

   Published

   June 20, 2024, 1:15 p.m.

   ...Solar, G., Giraldo, R., Ruiz-Echevarría, M. J., Espinosa, M., & Díaz-Orejas, R. (1998). Replication and...

8. Hot Plasmids Spring 2024

   Type

   Blog Post

   Published

   May 23, 2024, 1:15 p.m.

   ...high fidelity during action potentials of fast-spiking neurons. The same A-to-D mutation in the related...

9. Advanced Uses of Cre-lox and Flp-FRT - A Neuroscientist’s View

   Type

   Blog Post

   Published

   Oct. 19, 2017, 1:54 p.m.

   ... Cardin, Jessica A. et al. 2009. “Driving Fast-Spiking Cells Induces Gamma Rhythm and Controls Sensory...

10. Antibiotic Resistance: An Old Solution but a New Problem

    Type

    Blog Post

    Published

    Nov. 10, 2016, 3:30 p.m.

    ...Antibiotic resistance is defined as microbial survival despite exposure to antibiotics designed to kill them or...

11. Changing Labor Laws Bring Increased Postdoc Wages

    Type

    Blog Post

    Published

    Oct. 25, 2016, 2:30 p.m.

    ...salaries at or above $50,000. Boston Children’s Hospital is the only part of the Harvard group that has...

12. The Challenges of Cell Culture

    Type

    Blog Post

    Published

    May 5, 2016, 2:30 p.m.

    ... Crown Publishers, 2010. 2. Gold, Michael. "A conspiracy of cells." State University of New York Press...

13. Avoiding the Dark Side of Fluorescent Protein Fusions with mOX FPs

    Type

    Blog Post

    Published

    Oct. 27, 2015, 3 p.m.

    ...for subcellular environment. Currently, she is a SPIRE postdoctoral fellow at the University of North Carolina...

14. Important Considerations in Optogenetics Behavioral Experiments

    Type

    Blog Post

    Published

    Oct. 1, 2015, 2:30 p.m.

    ...science writing. Derek is also a pianist and an aspiring composer. View his blog drsimonsaysscience.org...

15. Data Freedom: The Expansion of Data Sharing in Research Publications

    Type

    Blog Post

    Published

    Aug. 5, 2014, 6:51 p.m.

    ...Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, Canada where he studies protein-serine...

16. Replacing Paper: Tips for Choosing an Electronic lab Notebook

    Type

    Blog Post

    Published

    July 10, 2018, 1:08 p.m.

    ...to insufficient and non-standard record keeping despite scientist’s best efforts. We all have software ...

17. Fluorescent Proteins 101: GFP Fusion Proteins - Making the Right Connection

    Type

    Blog Post

    Published

    April 9, 2019, 1:13 p.m.

    ...necessary for post-translational modifications. Despite these potential issues, GFP has been used successfully...

18. Five Popular Model Organisms, Part 2

    Type

    Blog Post

    Published

    Sept. 29, 2020, 1:15 p.m.

    ...regenerate complex structures such as limbs, the spinal cord, and internal organs including the heart, ...

19. Four Ways to Package Transgenes That Exceed the Size Limit of Adeno-associated Virus

    Type

    Blog Post

    Published

    Sept. 1, 2020, 1:15 p.m.

    ...physical size of the genomes is still ~4.7kb. But despite this, larger functional transgene products were...

20. 3 Tips to Improve HDR Efficiency for CRISPR Editing in Human Cells

    Type

    Blog Post

    Published

    Sept. 5, 2017, 1:58 p.m.

    ...only saw incorporation of the blocking mutation. Despite the fact that both the blocking mutation and our...