We narrowed to 330 results for: ARIA

... other orthologs. Ma et al. tested their dCas9 variants using gRNAs specific for telomeric sequences and...

...-true tools We use Python, Django, Apache, and MariaDB. Using tried-and-true tools means less time getting...

... requires that sex be included as a biological variable in all NIH-funded research. Janine Clayton, Director...

...Our paper shows we can easily make orthogonal variation. The first one worked in each case. Sometimes ...

...‘core’ complex is composed of a tightly-bound invariant group of proteins, whereas the more loosely bound...

... allows researchers to assemble and test many variables all at once. CRISPR CRISPR arrays and libraries...

... to 49% fidelity, with significant lot-to-lot variation. Additionally, this assembly, which used only ...

...then mutagenize the NFIX gene and test whether variants of unknown significance (VUSs) that are frequently...

... stability allowing for minimized basal FRET variability, and is a good choice for FRET assays where a...

...multitude of known AAV serotypes that have slight variations in their viral capsids. Novel forms of AAV capsids...

...originally described by Theodor Förster in 1948 as a variation of the more commonly observed light emission by...

... the pool but instead selectively sequence the variable portion of the plasmid in the pool - ex. the gRNA...

...in worms than split-sfCherry3. It was created by Maria Ingaramo, Jerome Goudeau, Cynthia Kenyon, and colleagues...

...CRISPR activation uses dCas9, a CRISPR protein variant lacking its endonuclease ability, to bind to genes...

...Cpf1 is also sensitive to single mismatches, but variably so, with Kleinstiver et al. reporting that Cpf1...

...important role in RNA processing and contributes to variability in RNA half-life, and ultimately gene-expression...

...transposon methylation underlies the mantled somaclonal variant of oil palm." Nature 525.7570 (2015): 533-537. ...

...-based biosensor for cAMP dynamics. The mGold2 variants significantly enhanced photostability — 25-fold...

...improved kinetics and responsivity in screening ASAP3 variants. B) Electrical and optical recordings of spontaneous...

...the amount of cloning, another option is to use variants of Cas9, like split Cas9, or a smaller Cas9 ortholog...