We narrowed to 335 results for: CAPS
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TypeBlog PostPublishedNov. 2, 2023, 1:15 p.m....Clinical trials are underway to explore CRISPR’s capacity for both classes of edits in cancer therapy. Blood...
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Viral Vectors 101: Calcium Sensors
TypeBlog PostPublishedAug. 10, 2023, 1 p.m....studying the brain, muscles, or intracellular landscape, remember: Keep Ca+2lm and Ca+2rry on! References... -
Viral Vectors 101: Chemogenetics
TypeBlog PostPublishedJuly 11, 2023, 1:15 p.m....expressed in the brain, it is necessary to use ligands capable of crossing the blood-brain barrier. Another consideration... -
Plasmids 101: In-house NGS Plasmid Quality Control Now at Addgene
TypeBlog PostPublishedApril 6, 2021, 12:30 p.m....Sequencing (CPS) workflow and yield sufficient data to capture the entire viral genome. The full details of that... -
How to Prepare for an Industry Interview
TypeBlog PostPublishedJuly 9, 2020, 1:15 p.m....a theme too, which is something not inherently captured by the STAR method. I like to think of the theme... -
Synthetic promoter AAVs for cell-type specific expression in retinal cells
TypeBlog PostPublishedMarch 12, 2020, 1:15 p.m....focused on modifying the outside protein shell, or capsid, of the virus so that it only enters and delivers... -
CRISPR Activators: A Comparison Between dCas9-VP64, SAM, SunTag, VPR, and More!
TypeBlog PostPublishedOct. 6, 2020, 1:15 p.m....fused to CBP, an histone acetyltransferase domain capable of rearranging chromatin structure. This method... -
Split Fluorescent Proteins for Studying Protein-Protein Interactions
TypeBlog PostPublishedMay 3, 2022, 1:15 p.m....Description Article PI Blue EBFP2 EBFP2(1-10) and Capri(1-10) for use with GFP(11) Multiplexed labeling ... -
Tips for Technical Support Calls
TypeBlog PostPublishedSept. 20, 2016, 2:39 p.m.... science, but we don’t have the resources to recapitulate the experiments performed by our thousands of... -
Adapting Toehold Switches to Detect Zika Virus
TypeBlog PostPublishedAug. 30, 2016, 2:30 p.m....technologies that has transformed the assay’s capabilities. Specifically this includes primer directed ... -
Hot Plasmids: Summer 2025
TypeBlog PostPublishedAug. 28, 2025, 1:15 p.m....with BioRender.com. Addgene has tested these capsid plasmids in vitro and uses them in our own AAV ... -
Hot Plasmids: Winter 2025
TypeBlog PostPublishedMarch 11, 2025, 1:15 p.m....PE2max-NC and ePEmax3 optimized for dicots. NC: nucleocapsid RNA chaperone, RT: reverse transcriptase. Right... -
Degrading DNA with Cascade-Cas3
TypeBlog PostPublishedFeb. 11, 2025, 2:15 p.m....through DNA degradation, thanks to the unique capabilities of Cas3 and its partner in crime, Cascade. Find... -
Plasmids 101: Protein Expression
TypeBlog PostPublishedJune 7, 2018, 1:17 p.m.... work with than mammalian cells, and are often capable of modifying complex proteins unlike bacterial ... -
xCas9: Engineering a CRISPR Variant with PAM Flexibility
TypeBlog PostPublishedMarch 28, 2018, 6:52 p.m....residues D10 and H840. To ensure that the clones were capable of cleavage, they tested the clones against an ... -
Of Myc and Men
TypeBlog PostPublishedJan. 19, 2023, 2:15 p.m....of antibodies as tools allowed us to detect and capture proteins of interest to better study them in vivo... -
3D Printing Meets CRISPR Cas9
TypeBlog PostPublishedOct. 17, 2017, 12:55 p.m.... of Cas9 – primed for cleavage. This structure captures the displaced non-target DNA strand and shows ... -
No Llamas Required - Synthetic Nanobodies Against Membrane Proteins
TypeBlog PostPublishedJune 18, 2020, 1:15 p.m....anti-Myc antibodies bound to an ELISA plate to capture Myc-tagged sybodies. Then, the biotinylated target... -
Academic vs. Industry Postdocs
TypeBlog PostPublishedNov. 13, 2018, 1:22 p.m....academia, however, writing papers and grants is an inescapable and essential part of being able to continue ... -
Starter guide to induced pluripotent stem cells (iPSCs) part 1: A renaissance in regenerative medicine
TypeBlog PostPublishedOct. 30, 2018, 1:04 p.m....undifferentiated “stem” state and, Their potency or capability to differentiate into specialized cell types ...