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Epigenetic modifications are an additional layer of control over gene expression. Targeted epigenetic modification is possible using CRISPR tools from Addgene!

June 24, 2020, 5:45 p.m.

Learn how to use Easi-CRISPR to generate mouse knock-in and conditional allele models.

April 5, 2018, 12:42 p.m.

Discover the tools you need to perform plant genome engineering with CRISPR.

Oct. 11, 2016, 2:30 p.m.

Three studies recently showed that CRISPR can be used to treat Duchenne muscular dystrophy in mice. Learn about the work and obstacles to application.

Jan. 26, 2016, 3:30 p.m.

Learn what non-model organisms are, why scientists use them, and what they can teach us.

July 21, 2026, 1:15 p.m.

Long-read sequencing has allowed researchers to identify plasmid dimers and multimers. Learn about them - and how to troubleshoot - in this blog post.

Jan. 10, 2023, 2:15 p.m.

Learn about the sources of spontaneous recombination and optimizing Cre-recombinase dependent AAV vector expression in vivo.

Nov. 2, 2021, 1:15 p.m.

Take a look at the developments in genome engineering throughout history and the parallels in science fiction.

Feb. 25, 2020, 2:15 p.m.

Learn about some of the factors you should take into consideration when choosing the appropriate AAV for your next experiment.

June 13, 2017, 2:30 p.m.

Learn how to select the plasmid purification kit that best suits your needs!

May 27, 2025, 1:15 p.m.

Adeno-associated virus (AAV) vector serotypes can help you target specific cell types through their tissue tropism.

Jan. 16, 2025, 2:15 p.m.

Get perspectives and possibilities for future action from scientists and other citizens who participated in the March for Science.

Oct. 24, 2017, 1:54 p.m.

Ready to let your tags do the work for you? Learn about self-labelling protein tags and how they can give you flexibility in your experimental approach!

April 16, 2024, 1:15 p.m.

Need help with the plasmid deposit process at Addgene? Consult this post for an in-depth walk through the entire process.

Feb. 27, 2024, 2:15 p.m.

Learn about the csRNP epitope tagging method - a new and efficient way to tag endogenous genes using CRISPR.

June 28, 2018, 3:01 p.m.

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

Nov. 6, 2018, 1:12 p.m.

A deep dive into qPCR with a focus on analysis, chemistries, and bench tips.

Sept. 29, 2022, 1:15 p.m.

Dr. Le Cong, first author on a seminal CRISPR article from Dr. Feng Zhang's lab, answers FAQs about the genome editing technology.

March 13, 2014, 4:08 p.m.

Check out all of the plasmids featured in our hot plasmids articles from 2016.

Dec. 22, 2016, 3:03 p.m.

Read on for a sampling of some of the exciting new plasmid technologies that have come through our doors in 2015.

Dec. 23, 2015, 3:30 p.m.