We narrowed to 461 results for: PAC;

...distance in the placement of plasmid elements can impact expression levels and consequently convolute the... different lentiviral plasmid backbone elements impact viral titer and to compare different Cas enzymes...

... formation slightly. Designing the sgRNA with a spacer that only binds the edited strand, as in the PE3b...Phage-assisted evolution and protein engineering yield compact, efficient prime editors. Cell, 186(18), 3983-4002...

...multiplex your reference genes to save on plate space. For many cell lines and tissue types, appropriate...your reference gene set can save significant plate space and may be worth the initial effort of setting it...

...combination of all 11 att pairs in series with unique spacer sequences (pMemoryArray) gives a DNA sequence capable...compartment (e.g. the plasma membrane, the extracellular space, or the lysosomes) can take many paths. Understanding... to other viral systems due to its large cargo capacity, minimal cytotoxicity, and broad host-tropism....

... Gateway-Compatible Toolbox Podcast Segment The impact of KLF4 N-terminal variants on iPSC generation ... expression levels; this altered stoichiometry impacted reprogramming and global gene expression patterns...

... gave to me: efficient CRISPR editing with a hypercompact Cas12f1 and engineered guide RNAs. On the sixth...

... deeply values our community and recognizes the impact of this decision. We realize that with this move...

...this year! All winners receive an Addgene care package with Addgene mugs and some delicious hot chocolate...

...Brook, and Angela are co-leading "Making a Greater Impact Using Clear and Accessible Scientific Writing" ...

...retroviral particles. Use in conjunction with a packaging vector such as pCMV-dR8.2 dvpr (lentiviral) or...

...!   CRISPR Cheat Sheet Clustered Regularly Interspaced Short Palindromic Repeats: Sequences of DNA found...

...plasmids in a way that can potentially have a direct impact on human health and look forward to hearing from...

...studies developmental gene regulation with Dr. Angela DePace in the Department of Systems Biology, and he tweets...

... disorders” in Ghana. We’re excited to see what impact Dr. Bengyella’s work will have on women’s health...

...near future, we hope to eliminate much of white space on this map and increase plasmid sharing across ...

.... The four winners will receive a holiday care package from Addgene. We hope all of our entrants had fun...

...data to share in grant proposals or to demonstrate impact in annual reports. While the raw data is, of course...

...can lead to cultural shifts that can have bigger impacts. For example, if you joined an office where everyone...

...researchers to share how these funding changes are impacting your work and what support would be most valuable...

... process, so you can work through it at your own pace. To submit, simply click "Contribute Data."    ...