We narrowed to 402 results for: LARGE;

...institution/funding source. Major equipment includes large centrifuges, sequencers and analyzers, and any ultra...

...SpRY variants of Cas9. With many PAMs available, a large number of gRNAs could be screened for the most efficient...federal regulators. But the speed is impressive on a larger scale, too. The first paper reporting genome editing...

...double-stranded DNA transgene is incorporated into a large complex of both viral and cellular proteins and ...enzymes that are proteolytically processed from the larger protein: PR (protease), RT (reverse transcriptase...

...bind to your biotinylated antibody. This creates a large meshwork of biotin-avidin complexes bound to your...

...cells compared to dead cells. As a result, the largely negative live cells can still be easily gated on...

...Both subunits have short intracellular ends and large ectodomains containing ligand-binding heads and ...

...frequency of 5%. Your experiment involves making a large sgRNA library to thousands of genes and targeting...

...something should be communicated is necessary in a large organization, because confirming that every person...

...blocks for engineered proteins. This flexibility is largely due to scFvs being smaller than antibodies. scFvs...

...changes in enzyme function can lead to surprisingly large fitness effects during adaptive evolution of antibiotic...

...Tomida, J., et al. "Detection of phosphorylation on large proteins by Western blotting using Phos-tag containing...

...modulate biological processes, but it did not show large changes in binding affinity with light stimulation...advantageous compared to other viral systems due to its large cargo capacity, minimal cytotoxicity, and broad ... CRISPR-Display uses the dCas9 enzyme to deploy large RNA cargos to specific DNA loci. In CRISPR-Display...

... With 143 plasmids deposited from this paper, a large menu of tool and control constructs is available...discovered that disruption of the nucleolus — the largest biomolecular condensate in human cells — causes...

...endoplasmic reticulum quality control navigate a large and interconnected system of dynamic and redundant...

...on many different levels - it’s hard to process large amounts of information and, from a SciComm perspective...results. As biological researchers deal with larger and larger datasets and use computer based analysis techniques...

...models remain more difficult to make. For example, large insertions, like a fluorescent protein knock-in,...

...therefore determines the timing of gene expression and largely defines the amount of recombinant protein that ...

... to reduce false positive rates and control for large numbers of comparisons. The Bonferroni does this...arranging all calculated p values from smallest to largest and ranking them (1 being the smallest value). ...calculates the cut off for significance by finding the largest p value where its rank divided by the total number...

...) NLS-Sa dCas9-NLS-LSD1. LSD1 is a particularly large protein, and this fusion allows for packaging into...genomic targets. These two vectors are part of the larger pMVP/pMAGIC cloning system, which contains Cas9...

... without causing issues associated with cloning large fragments. After fragmentation, repair sheared ends...