We narrowed to 820 results for: APP

... that the proportion of highly cited articles appearing in lower-prestige journals has risen steadily ...

...curated information about AAV usage in research applications. Scientists around the world can upload AAV ...

... methyltransferase substrates. We’re incredibly happy that lentiCRISPR v2 is being put to such great use...

...starting a forum where non-scientists can directly approach scientists and doctors with their questions and...

...inhibitors Using a bioinformatics and a screening approach, the Jennifer Doudna lab identified three different...

... highlight a subset of these tools for plasmid mapping, DNA/protein databases, DNA sequence manipulation...

...easy to multiplex. Their design allows flexible swapping of fluorescent proteins and multiplexing is simple...

...Chapter 8: The importance of a mix of research approaches. Why researchers should have a mix of high-risk...

...generation of a gRNA that will target SpCas9 to the approrpriate cleavage site). Finally, in addition to the ...

...milestones remind us of the extraordinary impact that happens when scientists come together to share their work...

... toolkit named ORANGE (Open Resource for the Application of Neuronal Genome Editing) mediates targeted...

... my first day and meet everyone but this never happened. I actually started at a later date and worked...

...suggestions for us, feel free to comment below. Happy reading! Tyler J. Ford ...

...feel they are wasting their time. The manager may appear to be too busy to be receptive.   Whatever the ...

...opportunities for advancement, challenges and disappointments. These more personal questions can elicit the...

... Figure 1: Schematic showing the X-CHIME approach. Figure from LaFleur, et al. 2024.   The X-CHIME...

...specific topics discussed during the interview. Happy listening! Listen to the interview with Science ...

...comprehensive review of affinity tags and microbial applications." Biotechnology journal 7.5 (2012): 620-634....

...Years of Plasmid Sharing Or read more about what happens Inside Addgene   ...

... few of those have been trips to breweries who happily exchange our expertise with lots of free beer.”...

... used protocols & references easy to find It’s happened to all of us. It’s your first day back in the ...

...it is Yoda who is singled out as a bad mentor. Apparently, a good Jedi does not necessarily an excellent...

...containing the modifying sequence flanked by approximately 50 base pairs of sequence homologous to the ...

.... Through an expansion of our export license application service, we’re pleased to announce that we are...

...). IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells...

...experiment, that you can find what you need and feel happy and inspired to tackle your next science challenge...

...is based in Canada, much of the information is applicable to researchers worldwide. “COVID-19 has spread...

...tubulin-GAL4. For Dre, Flp, KD, R, B2 and B3, approximately 50% of offspring carried both the recombinase...

...YFP) to the new and improved fruit colors (e.g., apple, papaya, and tomato) and the photoactivatable fluors...

... lentiviral libraries and their demonstrated application offer proof-of-principle that CRISPR-Cas9 can...

...determination, don’t generally affect antibody applications like ELISAs or Western blots, they are key in...

...discovery Present drug discovery takes one of two approaches. The first route involves identifying a gene/...

...resistance genes, toxin genes, and the sacB gene). By tapping into nature’s toolbox, scientists are finding more...

...neurotransmitter. But aside from DA’s famous role as the “happy hormone,” it’s also involved in reinforcement learning...

...spontaneous swimming  Researchers at the Isacoff lab applied optogenetics in zebrafish larvae to identify new...

...Commons 3.0 license, which requires users to give appropriate credit, provide a link to the license, and indicate...

... a Cas9 nickase and two gRNAs.  For nickase applications, a common question is: how should the gRNAs ...

... experiment to demonstrate the most exciting application for ARG’s: in vivo imaging. Specifically, arg1...

...directly use your DNA preparation in any downstream application involving enzymatic reactions, a valid alternative...

...broadly utilize plasmids across a wide range of applications. Some common plasmid types include cloning plasmids...