...a Lox-Stop cassette, resulting in the neurological deficits observed in Rett Syndrome. Restoring the MECP2...to Rett Syndrome, this blog post describes the history of Rett Syndrome research, the role of the MECP2... MECP2 gene by excision of the Stop cassette using tamoxifen-inducible Cre not only halted the neurological...precise amount of protein to each brain cell to restore physiological levels. Much research is now focused...

...efforts is the Golden Stopwatch Award to celebrate exemplary TTOs. Our new Golden Stopwatch Award recognizes...certain rights and protections for depositor and requestor alike. That’s why Addgene works closely with TTOs...agreement (usually) must be executed. The Golden Stopwatch Award highlights TTOs that accelerate science ...agreements quickly! If your TTO receives a Golden Stopwatch, consider sending an email to thank them--after...examples if possible Tell them about the Golden Stopwatch! Any organization that deposits with and/or [email protected] Congratulations to the Golden Stopwatch awardees! Congratulations to all of the winners...College of Medicine  Baylor College of Medicine Boston Children's Hospital  Brandeis University  Broad...

...attended and sponsored the Future of Research (FOR) Boston Symposium 2015. I personally participated as a ... Research Symposium On the FOR website, the FOR Boston 2015 organizers indicate that the main question...information gathered by Postdoctoral Associations around Boston - From Panel Session 2: Defining the Postdoc: An... Career Path Panel Two of the panels at the FOR Boston 2015 symposium, the Career Path Panel and the Early...type of failure. Final thoughts The FOR Symposium Boston 2015 shined a light on some of the many problems... Resources at Addgene  Read David Riglar's FOR Boston 2015 Blog Post Read Our Career Blog Posts Read ...

...system that utilized various cas genes not only to store a record of invading phages but to also destroy ...

...These are stormy times. It feels like we’re being buffeted by wind and waves and sometimes wonder if ...would be fully open and available to industry requestors as well. This is a time when we need as much ...Initiative was able to step in to be our “port in the storm.”  "Addgene is a unique resource for scientists ...whatever lies ahead this year. We can see signs of the storm passing. We’ve recently piloted Addgene’s new cloning...

...Addgene’s customer service philosophy Customer service can be a hassle. You finally make it through a...of our core values here is to provide unmatched customer support, as this is vital to ensuring that our...technical, or quality control issues. Improving customer support with self service We strive to make our...your busy schedule, you may not have the chance to stop what you’re doing and make a phone call or write...waiting for an answer. Luckily, there’s a trend in customer support to address this exact problem, and it’... customer support...

...Learn more about the history of plasmids and cloning: CSHL Meeting: Plasmids: History & Biology The Joshua...different experiments. Addgene was founded in order to store, QC, curate, and distribute them all in the name...eBook! In keeping with our goal of creating a one-stop reference guide for plasmids we've updated and added... history of plasmids...

...'s been about 14 years since I last attended a Keystone Meeting – far too long. Holding these meetings...course of the day. His talk, which focused on the history of genome engineering from ZFNs through TALENs ...synthetic biology. I've been answering biology customer service questions for nearly 7 years, and my colleagues...represented engineering first and foremost, from the custom software used to design complex genetic circuitry... of the book on my way to the meeting, and its history of code making and code breaking is wonderfully...increasingly important field.  Interested in Addgene's Keystone Poster?  We'll be sharing the poster with our...

...sell at farmers markets), and serious ideas (how to stop rhino horn poaching using biotechnology) were thrown... we decided to make education and outreach a cornerstone of our business, because we are building this...excited to see what the next few months have in store for us. If you’re thinking about making the switch...

...during storage over prolonged periods of time, especially at room temperature or at 4°C. Storing DNA: temperature...way to store and elute the DNA. References Murakami M (2013) Evaluation of DNA Plasmid Storage Conditions...and it will impact the time you will be able to store your sample without having substantial degradation...things when you elute your DNA: where you plan to store it and for how long. The most common solution is...