We narrowed to 262 results for: htt

...sponsored":false,"url":{"content_id":null,"href":"https://www.addgene.org/depositor-collections/allen-institute-aav-enhancers...allen-institute-aav-enhancers/","href_with_scheme":"https://www.addgene.org/depositor-collections/allen-institute-aav-enhancers...for genetic access to cortical cell types. Cell. https://doi.org/10.1016/j.cell.2025.05.002 Hunker, A. ...perturbing striatal cell types and circuits. Neuron https://doi.org/10.1016/j.neuron.2025.04.035 Graybuck,...cell-subclass-specific labeling. Neuron, 109(9), 1449-1464.e13. https://doi.org/10.1016/j.neuron.2021.03.011 Mich, J. ...primate neocortex. Cell Reports, 34(13), 108754. https://doi.org/10.1016/j.celrep.2021.108754 Panigrahi...the known and the unknown. Genome Biology, 22(1). https://doi.org/10.1186/s13059-021-02322-1  Pennacchio...

.... Science (New York, N.Y.), 339(6121), 819–823. https://doi.org/10.1126/science.1231143  Gaudelli, N. ...without DNA cleavage. Nature, 551(7681), 464–471. https://doi.org/10.1038/nature24644  Gaudelli, N. M., ...application. Nature Biotechnology, 38(7), 892–900. https://doi.org/10.1038/s41587-020-0491-6  Komor, A. C...double-stranded DNA cleavage. Nature, 533(7603), 420–424. https://doi.org/10.1038/nature17946  Lander, E. S. (2016...2016). The Heroes of CRISPR. Cell, 164(1), 18–28. https://doi.org/10.1016/j.cell.2015.12.041  Musunuru, ...England Journal of Medicine, 392(22), 2235–2243. https://doi.org/10.1056/NEJMoa2504747  Rees, H. A., Wilson...base editors. Science Advances, 5(5), eaax5717. https://doi.org/10.1126/sciadv.aax5717  Richter, M. F....

...multicellular interactions. Neuron, 113(16), 2599–2620.e7. https://doi.org/10.1016/j.neuron.2025.05.019    Unveiling...mitochondria transfer. Nature, 623(7986), 283–291. https://doi.org/10.1038/s41586-023-06537-z Hoover, G.... during cancer metastasis. Nature, 644 252–262. https://doi.org/10.1038/s41586-025-09176-8 Spees, J. ...National Academy of Sciences USA, 103(5), 1283–1288. https://doi.org/10.1073/pnas.0510511103      Red calcium...multiplexing capabilities. bioRxiv 2024.12.16.628673. https://doi.org/10.1101/2024.12.16.628673 Zhou, S., Zhu...single-cell resolution. PLoS Biol. 23(4): e3003048. https://doi.org/10.1371/journal.pbio.3003048   Micropeptide...rare genetic diseases. Nature, 614(7948), 564–571. https://doi.org/10.1038/s41586-022-05682-1 Zhang, Y., ...

...methylated somatic enhancers. Nat Genet 52, 819–827. https://doi.org/10.1038/s41588-020-0639-9.  Feinberg A...from their normal counterparts. Nature 301, 89–92. https://doi.org/10.1038/301089a0. Galonska C, Charlton...methyltransferase footprints. Nat Commun 9, 597. https://doi.org/10.1038/s41467-017-02708-5 Hrit J, Goodrich...activity and function in development. eLife 7:e34870. https://doi.org/10.7554/eLife.34870.  Kaas GA, Zhong C... and Memory Formation. Neuron 79, 6 P1086-1093. https://doi.org/10.1016/j.neuron.2013.08.032.  Morita ...catalytic domain fusions. Nat Biotechnol 34, 1060–1065. https://doi.org/10.1038/nbt.3658. Sapozhnikov DM, Szyf...methyltransferase with CRISPR/dCas9. Nat Commun 12, 5711. https://doi.org/10.1038/s41467-021-25991-9. Spruijt CG...

...CRISPR-Cas system. Nucleic Acids Research 41:7429–7437 . https://doi.org/10.1093/nar/gkt520 Chavez A, Scheiman ...transcriptional programming. Nat Methods 12:326–328 . https://doi.org/10.1038/nmeth.3312 Chavez A, Tuttle M,...activators in multiple species. Nat Methods 13:563–567 . https://doi.org/10.1038/nmeth.3871 Konermann S, Brigham...engineered CRISPR-Cas9 complex. Nature 517:583–588 . https://doi.org/10.1038/nature14136 Perez-Pinera P, Kocak...transcription factors. Nat Methods 10:973–976 . https://doi.org/10.1038/nmeth.2600 Qi LS, Larson MH, Gilbert...Control of Gene Expression. Cell 152:1173–1183 . https://doi.org/10.1016/j.cell.2013.02.022 Sajwan S, Mannervik...system differ in target preference. Sci Rep 9: . https://doi.org/10.1038/s41598-019-54179-x Tanenbaum ME...

...enhanced multiplex immunolabeling of brain. eLife 8: . https://doi.org/10.7554/elife.43322 Baker M (2015) Reproducibility...Blame it on the antibodies. Nature 521:274–276 . https://doi.org/10.1038/521274a Begley CG, Ellis LM (2012...preclinical cancer research. Nature 483:531–533 . https://doi.org/10.1038/483531a Bradbury A, Plückthun ...antibodies used in research. Nature 518:27–29 . https://doi.org/10.1038/518027a Bradbury AM, Plückthun...validate recombinants once. Nature 520:295–295 . https://doi.org/10.1038/520295b Bradbury ARM, Trinklein... functional variable regions. mAbs 10:539–546 . https://doi.org/10.1080/19420862.2018.1445456 Crosnier...mouse monoclonal antibodies. BMC Biology 8:76 . https://doi.org/10.1186/1741-7007-8-76 Greenfield, E.A...

...content_id":null,"href":"https://datahub.addgene.org/","href_with_scheme":"https://datahub.addgene.org/"...inflammation. Nature Reviews Immunology, 10(5), 301–316. https://doi.org/10.1038/nri2761 Chiu, M. L., Goulet, D...Engineering therapeutics. Antibodies, 8(4), 55. https://doi.org/10.3390/antib8040055 Holliger, P., & Hudson...domains. Nature Biotechnology, 23(9), 1126–1136. https://doi.org/10.1038/nbt1142 Kang, B. H., Lax, B. M...maturation. Methods in Molecular Biology, 29–62. https://doi.org/10.1007/978-1-0716-2285-8_2 McMahon, C...Structural & Molecular Biology, 25(3), 289–296. https://doi.org/10.1038/s41594-018-0028-6 Packer, M. S...proteins. Nature Reviews Genetics, 16(7), 379–394. https://doi.org/10.1038/nrg3927 Wang, Y., Xue, P., Cao...

...retroviruses. Microbiological Reviews, 56(3), 375–394. https://doi.org/10.1128/MR.56.3.375-394.1992. PubMed PMID...Current State and Perspectives. Viruses, 13(7), 1288. https://doi.org/10.3390/v13071288. PMID: 34372494. Prussin...Environmental Science & Technology Letters, 2(4), 84. https://doi.org/10.1021/ACS.ESTLETT.5B00050. PubMed PMID...of the United States of America, 54(1), 137–144. https://doi.org/10.1073/PNAS.54.1.137. PubMed PMID: 4285422...precursor protein. The EMBO Journal, 16(16), 5113–5122. https://doi.org/10.1093/EMBOJ/16.16.5113. PubMed PMID:...virus DNAs. Journal of Virology, 14(5), 1132–1141. https://doi.org/10.1128/JVI.14.5.1132-1141.1974. PubMed.... Journal of Molecular Biology, 79(1), 163–183. https://doi.org/10.1016/0022-2836(73)90277-5. PubMed PMID...

...D3 receptors. Scientific Reports, 10(1), 21842. https://doi.org/10.1038/s41598-020-78827-9  Breen, C. ...ligand-binding assay. Scientific Reports, 6, 25769. https://doi.org/10.1038/srep25769  Grimm, J. B., & Lavis...fluorescent labels. Nature Methods, 19(2), 149–158. https://doi.org/10.1038/s41592-021-01338-6  Grimm, J. ... vivo imaging. Nature Methods, 14(10), 987–994. https://doi.org/10.1038/nmeth.4403  Hayashi-Takanaka, ... partner for live cell imaging. PLoS ONE, 9(9). https://doi.org/10.1371/journal.pone.0106271  Heinrichs...fluorescent dyes. Nature Cell Biology, 11(S1), S7. https://doi.org/10.1038/ncb1939  Liu, X., Yang, L., Long...mammalian cells. Biophysics Reports, 3(4–6), 64–72. https://doi.org/10.1007/s41048-017-0037-8  Lucidi, M.,...

...Journal of Biological Chemistry, 273(14), 8447–8453. https://doi.org/10.1074/jbc.273.14.8447  Jain, A., & Srivastava...plasmids. FEMS Microbiology Letters, 348(2), 87–96. https://doi.org/10.1111/1574-6968.12241  Keen, N. T., ...in Gram-negative bacteria. Gene, 70(1), 191–197. https://doi.org/10.1016/0378-1119(88)90117-5  Lale, R....Molecular Biology (Clifton, N.J.), 765, 327–343. https://doi.org/10.1007/978-1-61779-197-0_19  Meyer, R...host-range IncQ plasmids. Plasmid, 62(2), 57–70. https://doi.org/10.1016/j.plasmid.2009.05.001  Meyer, ...Molecular & General Genetics: MGG, 152(3), 129–135. https://doi.org/10.1007/BF00268809  Prior, J. E., Lynch...Biotechnology and Bioengineering, 106(2), 326–332. https://doi.org/10.1002/bit.22695  Schmidhauser, T. J....

...RNA-targeting CRISPR effector. Science 353:aaf5573 . https://doi.org/10.1126/science.aaf5573 Broughton JP, ... detection of SARS-CoV-2. Nature Biotechnology. https://doi.org/10.1038/s41587-020-0513-4 Chen JS, Ma ...-stranded DNase activity. Science 360:436–439 . https://doi.org/10.1126/science.aar6245 Gootenberg JS,... with CRISPR-Cas13a/C2c2. Science 356:438–442 . https://doi.org/10.1126/science.aam9321 Gootenberg JS,... Cas13, Cas12a, and Csm6. Science 360:439–444 . https://doi.org/10.1126/science.aaq0179 Myhrvold C, Freije...diagnostics using CRISPR-Cas13. Science 360:444–448 . https://doi.org/10.1126/science.aas8836 Niewoehner O, ...CRISPR-associated protein Csm6. RNA 22:318–329 . https://doi.org/10.1261/rna.054098.115 Shmakov S, Abudayyeh...

...and applications. Gene Therapy, 17(2), 150–157. https://doi.org/10.1038/gt.2009.135. PubMed PMID: 19847206...Expression. Viruses: Essential Agents of Life, 147–175. https://doi.org/10.1007/978-94-007-4899-6_7. PubMed Central...human cells. Nature Biotechnology, 31(9), 822–826. https://doi.org/10.1038/nbt.2623. PubMed PMID: 23792628...Journal of Clinical Investigation, 118(9), 3143–3150. https://doi.org/10.1172/JCI35798. PubMed PMID: 18688286...infection. Journal of Virology, 70(2), 721–728. https://doi.org/10.1128/JVI.70.2.721-728.1996. PubMed ...genes and local hotspots. Cell, 110(4), 521–529. https://doi.org/10.1016/s0092-8674(02)00864-4. PubMed ...American Society of Gene Therapy, 17(8), 1316–1332. https://doi.org/10.1038/mt.2009.122. PubMed PMID: 19491821...

...ABE8e. Nucleic Acids Research, 52(22):13931-13944. https://doi.org/10.1093/nar/gkae1066. Bryant, J., Herron...in vivo gene expression via adaptamers. bioRxiv. https://doi.org/10.64898/2025.12.21.695777 Doman, J. L...efficient prime editors. Cell, 186(18), 3983–4002. https://doi.org/10.1016/j.cell.2023.07.039 Gupta, A., ...breast cancer. Nature Genetics, 57(6), 1452–1462. https://doi.org/10.1038/s41588-025-02187-1 Ortega, P.,...catastrophe. Science Advances, 11(16), eadu0437. https://doi.org/10.1126/sciadv.adu0437 Pecori, R., Casati...tumor-specific neoantigens (editopes). bioRxiv. https://doi.org/10.1101/2023.03.16.532918 Pierce, S. E...disease-agnostic genome editing. Nature, 648(8092), 191–202. https://doi.org/10.1038/s41586-025-09732-2 Richter, M....

... editing. Nature Biotechnology, 40(5), 731–740. https://doi.org/10.1038/s41587-021-01133-w Anzalone, A...breaks or donor DNA. Nature, 576(7785), 149–157. https://doi.org/10.1038/s41586-019-1711-4 Chen, P. J.,...editing outcomes. Cell, 184(22), 5635-5652.e29. https://doi.org/10.1016/j.cell.2021.09.018 Choi, J., Chen... editing. Nature Biotechnology, 40(2), 218–226. https://doi.org/10.1038/s41587-021-01025-z Doman, J. L...efficient prime editors. Cell, 186(18), 3983-4002.e26. https://doi.org/10.1016/j.cell.2023.07.039 Lin, Q., Jin...in plants. Nature Biotechnology, 39(8), 923–927. https://doi.org/10.1038/s41587-021-00868-w Nelson, J. ...efficiency. Nature Biotechnology, 40(3), 402–410. https://doi.org/10.1038/s41587-021-01039-7 Pandey, S.,...

...(red/pink) staining. Image credit: Mark Perkins https://www.flickr.com/photos/occbio/7092385559 For...these resources.   Bruckner, M. Gram Staining. https://serc.carleton.edu/microbelife/research_methods...Protocols. American Society for Microbiology (2005). https://asm.org/getattachment/5c95a063-326b-4b2f-98ce-...Positive vs Gram Negative. Technology Networks (2019) https://www.technologynetworks.com/immunology/articles...) a000414 (2010). Cleveland Clinic. Gram Stain. https://my.clevelandclinic.org/health/diagnostics/22612...gram-stain Hardy, J. Gram’s Serendipitous Stain. https://hardydiagnostics.com/wp-content/uploads/2016/05...

...true" %}{% raw %}{"url":{"content_id":null,"href":"https://www.addgene.org/crispr/empty-grna-vectors/","type... and prime editors. Nat Biotechnol 38:824–844 . https://doi.org/10.1038/s41587-020-0561-9 Dempster JM,...CRISPR-Cas9 gene dependency data sets. Nat Commun 10: . https://doi.org/10.1038/s41467-019-13805-y Doench JG (...guide to genetic screens. Nat Rev Genet 19:67–80 . https://doi.org/10.1038/nrg.2017.97 Hanna RE, Doench JG...CRISPR–Cas experiments. Nat Biotechnol 38:813–823 . https://doi.org/10.1038/s41587-020-0490-7 Radzisheuskaya...transcriptional repression. Nucleic Acids Res 44:e141–e141 . https://doi.org/10.1093/nar/gkw583 Rees HA, Liu DR (2018...transcriptome of living cells. Nat Rev Genet 19:770–788 . https://doi.org/10.1038/s41576-018-0059-1 Veres A, Gosis...

...Methods, 1–9. https://doi.org/10.1038/s41592-023-02085-6. PMID: 38036853. Preprint: https://doi.org/10.21203...Biotechnology, 1–4. https://doi.org/10.1038/s41587-023-02018-w. PMID: 38081970. Preprint: https://doi.org/10.21203...Nature Biotechnology, 10.1038/s41587-023-01756-1. https://doi.org/10.1038/s41587-023-01756-1. PMID: 37095348...derived from StayGold. ResearchSquare (Preprint). https://doi.org/10.21203/rs.3.rs-3188559/v1.  Neurogenetic...brain. Nature Nanotechnology, 18, 1241–1251 (2023). https://doi.org/10.1038/s41565-023-01419-x. PMID: 37430038...in primates. Nature Communications, 14(1), 3345. https://doi.org/10.1038/s41467-023-38582-7. PMID: 37291094...

...comparison to AAV PHP.B. Gene Therapy, 25(5), 392–400. https://doi.org/10.1038/s41434-018-0028-5 de Backer, M...Hypothalamus. Human Gene Therapy, 21(6), 673–682. https://doi.org/10.1089/hum.2009.169 Gruntman, A. M., ...trials. Human Gene Therapy Methods, 26(2), 71–76. https://doi.org/10.1089/hgtb.2015.040 Initiative, F. B...Preparations. Human Gene Therapy Methods, 30(6), 214–225. https://doi.org/10.1089/hgtb.2019.105 Rumachik, N. G.,...and Clinical Development, 18(September), 98–118. https://doi.org/10.1016/j.omtm.2020.05.018 Tedersoo, L...scientific disciplines. Scientific Data, 8(1), 1–11. https://doi.org/10.1038/s41597-021-00981-0 Wright, J. ...formulation. Molecular Therapy, 12(1), 171–178. https://doi.org/10.1016/j.ymthe.2005.02.021 Zuk, P., Sanchez...

...transposon-encoded CRISPR–Cas system. Nature 577:271–274 . https://doi.org/10.1038/s41586-019-1849-0 Klompe SE, Vo...RNA-guided DNA integration. Nature 571:219–225 . https://doi.org/10.1038/s41586-019-1323-z Peters JE, Makarova...transposons. Proc Natl Acad Sci USA 114:E7358–E7366 . https://doi.org/10.1073/pnas.1709035114 Rubin BE, Diamond... Bacteria Within Microbial Communities. bioRxiv https://www.biorxiv.org/content/10.1101/2020.07.17.209189v2...CRISPR-associated transposases. Science 365:48–53 . https://doi.org/10.1126/science.aax9181 Strecker J, Ladha...CRISPR-associated transposases.” Science 368:eabb2920 . https://doi.org/10.1126/science.abb2920 Vo PLH, Ronda ...multiplexed bacterial genome engineering. Nat Biotechnol. https://doi.org/10.1038/s41587-020-00745-y Zhang Y, Sun...

...outcomes and assisting sgRNA selection is available at http://www.sunlab.fun:3838/BE_SMART/. Even more new DNA...repair proteins. Nature Communications, 12(1), 1384. https://doi.org/10.1038/s41467-021-21559-9 Huang, M. E...translocation. Nature Cell Biology, 26(2), 294–304. https://doi.org/10.1038/s41556-023-01342-2 Koblan, L. ...learning. Nature Biotechnology, 39(11), 1414–1425. https://doi.org/10.1038/s41587-021-00938-z Koblan, L. ...reconstruction. Nature Biotechnology, 36(9), 843–846. https://doi.org/10.1038/nbt.4172 Kurt, I. C., Zhou, R....human cells. Nature Biotechnology, 39(1), 41–46. https://doi.org/10.1038/s41587-020-0609-x Yang, C., Dong..., Baden-Wurttemberg, Germany), 9(26), e2202957. https://doi.org/10.1002/advs.202202957 Yuan, T., Yan, ...

.... Nature Reviews Microbiology, 20(11), 641–656. https://doi.org/10.1038/s41579-022-00739-4 References ...surveillance by CRISPR–Cas9. Nature, 603(7900), 343–347. https://doi.org/10.1038/s41586-022-04470-1 Cofsky, J. ...Structural & Molecular Biology, 29(4), 395–402. https://doi.org/10.1038/s41594-022-00756-0 Jiang, F., ...Mechanisms. Annual Review of Biophysics, 46, 505–529. https://doi.org/10.1146/annurev-biophys-062215-010822 ...Guide RNA and Target DNA. Cell, 156(5), 935–949. https://doi.org/10.1016/j.cell.2014.02.001 Osuka, S., ... CRISPR–Cas9. The EMBO Journal, 37(10), e96941. https://doi.org/10.15252/embj.201796941 Pattanayak, V....specificity. Nature Biotechnology, 31(9), 839–843. https://doi.org/10.1038/nbt.2673 Sternberg, S. H., LaFrance...

...by low-copy number plasmids. Plasmid 80:54–62 . https://doi.org/10.1016/j.plasmid.2015.03.007 Pubmed PMID...clusters. Molecular Microbiology 56:1430–1440 . https://doi.org/10.1111/j.1365-2958.2005.04643.x Pubmed...resistance plasmids in vivo. PLOS ONE 12:e0172913 . https://doi.org/10.1371/journal.pone.0172913 Pubmed PMID...Using Plasmid Incompatibility. PLoS ONE 7:e29875 . https://doi.org/10.1371/journal.pone.0029875 Pubmed PMID...incompatibility. Letters in Applied Microbiology 47:235–240 . https://doi.org/10.1111/j.1472-765x.2008.02426.x Pubmed...Current Opinion in Structural Biology 22:72–79 . https://doi.org/10.1016/j.sbi.2011.11.001 Pubmed PMID:...and host taxonomy. Frontiers in Microbiology 6: . https://doi.org/10.3389/fmicb.2015.00242 Pubmed PMID: ...

...3D SIM imaging. Nature Methods, 23(1), 143–152. https://doi.org/10.1038/s41592-025-02962-2 Xiong, H., ...advanced microscopy. Nature Methods, 22(6), 1288–1298. https://doi.org/10.1038/s41592-025-02676-5    Updated... storage in mammalian cells. Science, eadz9353. https://doi.org/10.1126/science.adz9353   An engineered...with one stop codon. Nature, 639(8054), 512–521. https://doi.org/10.1038/s41586-024-08501-x Lajoie, M....biological functions. Science, 342(6156), 357–360. https://doi.org/10.1126/science.1241459    Wine and dine... screening. Nature Communications, 13(1), 5255. https://doi.org/10.1038/s41467-022-33024-2 Drepanos, L...optimized Cas9 CRISPR knockout library design. bioRxiv. https://doi.org/10.1101/2025.08.26.672375   Neurexin ...

...Nucleases. G3 Genes Genomes Genetics, 3(4), 657–664. https://doi.org/10.1534/g3.112.005439  Cong, L., Ran,...CRISPR/CAS systems. Science, 339(6121), 819–823. https://doi.org/10.1126/science.1231143  Elliott, B.,... Molecular and Cellular Biology, 18(1), 93–101. https://doi.org/10.1128/mcb.18.1.93  Ran, F. A., Hsu...genome editing specificity. Cell, 154(6), 1380–1389. https://doi.org/10.1016/j.cell.2013.08.021  Ran, F. ...CRISPR-Cas9 system. Nature Protocols, 8(11), 2281–2308. https://doi.org/10.1038/nprot.2013.143 Sander, J. D.... genomes. Nature Biotechnology, 32(4), 347–355. https://doi.org/10.1038/nbt.2842  Soldner, F., Laganière...Parkinson Point mutations. Cell, 146(2), 318–331. https://doi.org/10.1016/j.cell.2011.06.019  Wang, H.,...

...substrate. ACS Chemical Biology, 7(11), 1848–1857. https://doi.org/10.1021/cb3002478 Kamada, Y., Tateishi...Degradation of Misfolded CFTR. Cells, 12(23), 2741. https://doi.org/10.3390/cells12232741  Kamio, T., Kono...Late-Onset Gastric Cancer. Cancer Medicine, 14(8). https://doi.org/10.1002/cam4.70793 Laissue, P. P., Alghamdi...fluorescence imaging. Nature Methods, 14(7), 657–661. https://doi.org/10.1038/nmeth.4344  Peach, C. J., Kilpatrick...British Journal of Pharmacology, 178(12), 2393–2411. https://doi.org/10.1111/bph.15426 Promega Corporation ...Proteins Using HiBiT CRISPR Cell Lines. Promega Notes. https://www.promega.com/resources/pubhub/2025/illuminating-transmembrane-proteins-using-hibit-crispr-cell-lines...human tissue and in vitro. Oncology Reports, 50(5). https://doi.org/10.3892/or.2023.8631 Tsien R. Y. (1998...

...Vulnerable Patients. Frontiers in Immunology, 13. https://www.frontiersin.org/articles/10.3389/fimmu.2022.885672Piché...Safety Assessment (pp. 519–542). Academic Press. https://doi.org/10.1016/B978-0-12-417144-2.00027-5van ... Challenges. The oncologist, 21(10), 1260–1268. https://doi.org/10.1634/theoncologist.2016-0061WHO. International...Enhancements. Frontiers in drug discovery, 2, 952326. https://doi.org/10.3389/fddsv.2022.952326Joubert, M. K...Antibody-Based Biotherapeutics. PloS one, 11(8), e0159328. https://doi.org/10.1371/journal.pone.0159328Groell, F....Pharmazeutische Verfahrenstechnik e.V, 130, 128–142. https://doi.org/10.1016/j.ejpb.2018.06.008Lu, RM., Hwang...treatment of diseases. J Biomed Sci 27, 1 (2020). https://doi.org/10.1186/s12929-019-0592-z  Resources Antibodies...

... Function Phenotypes. Plant Biology 7:251–257 . https://doi.org/10.1055/s-2005-837597 Li J-F, Chung HS... Silencing in Plants. Plant Cell 25:1507–1522 . https://doi.org/10.1105/tpc.113.112235 Morgens DW, Deans...for essential genes. Nat Biotechnol 34:634–636 . https://doi.org/10.1038/nbt.3567 Nakaoka Y, Miki T, Fujioka...Microtubule Generation. Plant Cell 24:1478–1493 . https://doi.org/10.1105/tpc.112.098509 Smits AH, Ziebell...in CRISPR knock outs. Nat Methods 16:1087–1093 . https://doi.org/10.1038/s41592-019-0614-5 Sztal TE, Stainier...genetic robustness. Development 147:dev186452 . https://doi.org/10.1242/dev.186452 Wilson RC, Doudna JA...RNA Interference. Annu Rev Biophys 42:217–239 . https://doi.org/10.1146/annurev-biophys-083012-130404 ...

...Resources References ASAPbio, Preprint Resource Center: https://asapbio.org/preprint-info ASAPbio, Preprints and... and Rapid Communication of COVID-19 research: https://asapbio.org/preprints-and-covid-19 Ettinger CL,...preprinting for early-career researchers. Biol Open. https://doi.org/10.1242/bio.059310 Fraser N, Mayr P, ...preprints: a survey of bioRxiv authors. bioRxiv. https://doi.org/10.1101/2021.09.07.459259 Sarabipour S...early career researcher perspective. PLoS Biol. https://doi.org/10.1371/journal.pbio.3000151 Sever R, ...bioRxiv: the preprint server for biology. bioRxiv. https://doi.org/10.1101/833400  Stern BM, O’Shea EK (2019...scientific publishing in the life sciences. PLoS Biol. https://doi.org/10.1371/journal.pbio.3000116 More resources...

...Designer Drugs. ACS Chemical Neuroscience 6:476–484 . https://doi.org/10.1021/cn500325v Goutaudier, R., Coizet...Specific Ligands. Eneuro, 6(5), ENEURO.0171-19.2019. https://doi.org/10.1523/ENEURO.0171-19.2019Jendryka M,...DREADD-based chemogenetics in mice. Scientific Reports 9: https://doi.org/10.1038/s41598-019-41088-2 Magnus C, Lee... clinical applications. Science 6436: eaav5282. https://science.sciencemag.org/content/364/6436/eaav5282...transgenic mice. Nature Biotechnology 17:165–169 . https://doi.org/10.1038/6165 Roth BL (2016) DREADDs for...for Neuroscientists. Neuron 89:683–694 . https://doi.org/10.1016/j.neuron.2016.01.040 Saloman, J. L., ...The Journal of Neuroscience, 36(42), 10769–10781. https://doi.org/10.1523/JNEUROSCI.3480-15.2016 Weston ...

...by an anti-CRISPR protein. Nature 546:436–439 . https://doi.org/10.1038/nature22377 Harrington LB, Doxzen...Inhibitor of CRISPR-Cas9. Cell 170:1224-1233.e15 . https://doi.org/10.1016/j.cell.2017.07.037 Li C, Psatha...Therapy - Methods & Clinical Development 9:390–401 . https://doi.org/10.1016/j.omtm.2018.04.008 Marino ND, ...CRISPR-Cas technologies. Nat Methods 17:471–479 . https://doi.org/10.1038/s41592-020-0771-6 Mayo-Muñoz D...islandicus Rod-Shaped Virus 2. Viruses 10:695 . https://doi.org/10.3390/v10120695 Pawluk A, Amrani N, ...Off-Switches for CRISPR-Cas9. Cell 167:1829-1838.e9 . https://doi.org/10.1016/j.cell.2016.11.017 Shin J, Jiang... an anti-CRISPR DNA mimic. Sci Adv 3:e1701620 . https://doi.org/10.1126/sciadv.1701620 Additional Resources...