Deaminet 2026: Breakthroughs in Base Editing, Deaminase Biology, and Therapeutic Translation
Type
Blog Post
Published
March 10, 2026, 1:14 p.m.
...specific residues in the reverse transcriptase polymerase domain as likely determinants of the enzyme’s...overextension trade-offs
The prime editor PE6d exhibits substantially increased processivity and editing efficiency...Cas9 binding and editing outcomes can diverge substantially, reinforcing the need for assays that capture...