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Showing: 21 - 22 of 22 results
  1. Corralling and Cornering the Goldilocks Antibody

    Type
    Blog Post
    Published
    Aug. 9, 2022, 1:15 p.m.
    ...unreliability: cross-reactivity (binds to non-target proteins), variability (separate batches can perform differently...relatively new technology that takes advantage of DNA sequencing to turn mAb clones into expression constructs...technology, it is important to show through qualitative data that they are a long-term solution to reproducibility...atlases/literature and is unrelated to the target protein, we categorize the antibody as having non-specific...atlas will enable scientists to have an intuitive guide for checking their staining and neuroanatomy without...you are interested to get involved by submitting data, sending antibodies, and/or working with Dr. Wu ... dedicated to creating a public and accessible database for low-cost, high-quality antibodies for IHC....
  2. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    Published
    Oct. 12, 2023, 1:15 p.m.
    ...well as the type of transgene delivered: fluorescent proteins, optogenetic sensors, CRISPR elements, etc...BBB via interactions with a similar protein called LY6C1. This protein is expressed in both BALB/cJ mice...psst… don't forget to submit your validation data to our Data Hub once you’re finished!) Good luck and happy...exists to prevent substances in the blood, like proteins and viruses, from crossing into the brain. While... miRNA target sites, and recombination target sequences, denoted by triangles] facilitate tissue or cell...option for your experiment? Look it up in Addgene’s Data Hub and the CLOVER repository of published systemic... it, cross the BBB through an endothelial cell protein called LY6A (Hordeaux et al., 2019; Huang et al...
Showing: 21 - 22 of 22 results