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Showing: 401 - 420 of 707 results
  1. Inside Addgene's 10 Year Anniversary Gala

    Type
    Blog Post
    Published
    July 3, 2014, 3:48 p.m.
    ... desserts. We enjoyed a video highlighting the changes at Addgene over the last 10 years as well as the...fruition. The concept, though relatively simple, changed the course of scientific research. What was once...
  2. What's New in CRISPR - September 2019

    Type
    Blog Post
    Published
    Sept. 10, 2019, 12:56 p.m.
    ...transcriptional activation and genome editing Yu Wang's lab developed drug inducible CRISPR/Cas9 systems... Jennifer Tsang...
  3. Who Gives a Tweet? 9 Facts About Scientists on Twitter

    Type
    Blog Post
    Published
    June 26, 2017, 1:31 p.m.
    ...Discipline. Biologists, neuroscientists, and ecologists (orange box) post tweets containing scientific domains ...network of life (green), physical (blue) and social (orange)  scientists largely cluster by discipline, suggesting...
  4. In Living Color: The Skinny on In Vivo Imaging Tools

    Type
    Blog Post
    Published
    March 27, 2014, 5:14 p.m.
    ...proteins that would fall within that near-infrared range, and that’s exactly what iRFPs achieved. Those proteins... proteins that operate within the 750 to 800 nm range, and his team is also looking in the direction of...
  5. Understanding GPCR Signaling Using TRUPATH

    Type
    Blog Post
    Published
    Dec. 14, 2020, 2:15 p.m.
    ...conformational change in the GPCR, leading to the activation of the Gα subunit. The activated Gα exchanges bound...
  6. What's the Best Way to Elute and Store Your Plasmid DNA?

    Type
    Blog Post
    Published
    June 4, 2020, 1:22 p.m.
    ...contamination.  Extreme pH can denature, break, and even change the DNA sequence. High pH favors the breakage of...for the sugar backbone of the DNA helix or even changes the DNA sequence through a mechanism called depurination...
  7. Sensing Neuronal Dopamine

    Type
    Blog Post
    Published
    July 30, 2019, 12:59 p.m.
    ...relatively slow and is not suited to detect rapid changes in DA concentration. To address this, researchers...29853555. PubMed Central PMCID: PMC6287765. Sun, Fangmiao, et al. "A genetically encoded fluorescent sensor...
  8. Bringing Sustainable Practices to the Lab: Recycling

    Type
    Blog Post
    Published
    Feb. 14, 2019, 2:35 p.m.
    ...are ever recycled, so adopting a few meaningful changes in the lab could make a big difference in our global...Many scientists are already leading the cultural change toward responsibility in our lab’s environmental...
  9. New CRISPR Web Resources and #12DaysofCRISPR Recap

    Type
    Blog Post
    Published
    Dec. 12, 2017, 3:13 p.m.
    ...blogs to keep them current. Here are some of the changes we’ve made: New CRISPR plasmid pages We’ve given...RNA targeting systems, RNA editing does not make changes to the genome, thus providing an avenue for temporary...
  10. Early Career Researcher Toolbox: Free Online Molecular Biology Tools

    Type
    Blog Post
    Published
    Sept. 12, 2023, 1:15 p.m.
    ...Sometimes DNA sequences need to be “cleaned up” or changed in some way before you can analyze them. These ...Data-optimized Assembly Design (DAD): This tool designs overhang sets for high complexity Golden Gate Reactions...
  11. Build Your CRISPR Vocabulary

    Type
    Blog Post
    Published
    July 2, 2024, 1:15 p.m.
    ...tracrRNA pair or an sgRNA. It is often used interchangeably with the term sgRNA. Seed sequence: The 8-10...cheat sheet for that! Resources Further reading Wang, J. Y., Pausch, P., & Doudna, J. A. (2022). Structural...
  12. We're Updating Our Hold for Publication Policy

    Type
    Blog Post
    Published
    June 24, 2025, 1:15 p.m.
    ...are distributed. Next month, we are making two changes to the policy that will make the process a bit ...updating our Hold for Publication policy with two changes that will help us ensure that plasmids don’t get...
  13. Sleeping Beauty Awakens for Genome Engineering

    Type
    Blog Post
    Published
    June 30, 2015, 2 p.m.
    ...sequences and then testing various combinations of changes. The basic functional version of the Sleeping Beauty...contain two SfiI restriction sites with different overhangs depending upon whether they are on the 3’ or 5...
  14. Summer SciComm Series: Master of SciComm

    Type
    Blog Post
    Published
    July 21, 2022, 1:15 p.m.
    ...past and chatting with individuals whose research ranged from wildlife conservation to abortion law to poetry...confluence of science and the world it hopes to change. Most researchers are aware of the importance of...
Showing: 401 - 420 of 707 results