We narrowed to 807 results for: APP

1. Fluorescent Biosensors for Measuring Autophagic Flux

   Type

   Blog Post

   Published

   Jan. 22, 2019, 2:41 p.m.

   ...on counting the number of autophagosomes. This approach, however, has inherent limitations because it ...

2. Hot Plasmids - June 2020 - Barcoded CRISPR Library, Sparse Cell Labeling, Calcineurin Reporter, and DNA Staining Dye Alternative

   Type

   Blog Post

   Published

   June 2, 2020, 1:15 p.m.

   ...population, it’s easier to visualize individual/non-overlapping cells. Until now, tools for doing this were labor-intensive...

3. Hot Plasmids September 2018 - Optogenetics, RNA Localization, Fluorescent Protein, and Base-editing Tools

   Type

   Blog Post

   Published

   Sept. 18, 2018, 1:33 p.m.

   ...cells, and has potential use for a wide range of applications in cellular biology. Van Haren J et al. Nature...

4. Summer SciComm Series: Master of SciComm

   Type

   Blog Post

   Published

   July 21, 2022, 1:15 p.m.

   ...science communicator—with an understanding of how to appeal to a given audience and how to utilize a wide array...

5. RUBY-Red Siliques

   Type

   Blog Post

   Published

   March 1, 2022, 2:15 p.m.

   ...culture), which is great for a wide variety of applications. But some techniques require you to select against...

6. Hot Plasmids and Viral Preps - September 2021

   Type

   Blog Post

   Published

   Sept. 21, 2021, 1:15 p.m.

   ...several MYC-dependent cancer cell lines. It can be applied for identification of essential MYC binding sites...

7. A New Optogenetic Tool Based on AraC Controls Gene Expression with Blue Light

   Type

   Blog Post

   Published

   June 17, 2021, 1:17 p.m.

   ...reached the level of expression needed for most applications.   Figure 1: With blue light, the VVD...

8. Addgene Receives NIH BRAIN Initiative Grant to Create Open-Access Recombinant Antibody Resource

   Type

   Blog Post

   Published

   May 25, 2021, 2:29 p.m.

   ...which can limit expansion into new services. “We appreciate NIH’s vision and support for this project. This...

9. Multifunctional Neural Fibers: Modulation from Gut to Brain

   Type

   Blog Post

   Published

   Aug. 31, 2023, 1 p.m.

   ...interfaces with the entire body, so the obvious next applications are to expand the tool to different brain-organ...

10. Antibodies 101: Chimeric Antibodies

    Type

    Blog Post

    Published

    April 25, 2023, 1:15 p.m.

    ...published, knockout validated, and work in your application. But…they are the same isotype and therefore ...

11. Using Addgene's New Viral Service for Your Research

    Type

    Blog Post

    Published

    Nov. 17, 2016, 3:30 p.m.

    ...preparations have worked well in my lab, including in applications where we have delivered them in vivo to the ...

12. Interview: Ed Boyden on Optogenetics, Neuroscience, and the Future of Neuroengineering

    Type

    Blog Post

    Published

    March 4, 2014, 4:49 p.m.

    ...a handle on some of these mysteries. Another application is clinical; can we find ways to treat patients...

13. New and Upcoming Viral Vectors - June 2019

    Type

    Blog Post

    Published

    June 18, 2019, 1:15 p.m.

    ...ligand-gated ion channels that can be activated with FDA-approved drugs. See our inventory of DREADDs / Chemogenetics...

14. Visualizing Genomic Loci with CRISPR-Sirius

    Type

    Blog Post

    Published

    April 18, 2019, 12:53 p.m.

    ...has been widely adapted for a wide variety of applications: base editing, CRISPR activation and inhibition...

15. Quantifying DNA? Here are Five DNA Quantification Methods to Consider

    Type

    Blog Post

    Published

    July 21, 2020, 1:15 p.m.

    ...you choose could be based on your downstream application, time, and instrument availability. UV absorbance...

16. Photosensitizer Induced Cell Ablation with FAP-TAP MG-2I-dL5**

    Type

    Blog Post

    Published

    Sept. 19, 2017, 1:20 p.m.

    ...by TUNEL staining.  The video below shows what happens to the zebrafish’s heartbeat and blood circulation...

17. Quick Guide to Working with Drosophila Part 2: Controlling Gene Expression in Flies with Gal4/UAS

    Type

    Blog Post

    Published

    July 21, 2017, 12:48 p.m.

    ...as overexpression of each gene individually. Applications of the Gal4/UAS system There are a number of...

18. How Dry Ice Affects Viral Vector Sample pH & How to Avoid It

    Type

    Blog Post

    Published

    June 20, 2017, 2:30 p.m.

    ... an upright position for 30 seconds, and then recapping the tubes prior to thaw. We compared vented and...

19. The Power Behind NGS Plasmid Validation: seqWell

    Type

    Blog Post

    Published

    April 19, 2017, 3:25 p.m.

    ... we’ve been working with Addgene to develop and apply our plexWell™ Library Preparation Technology for...

20. Creating accessible biology activities in schools with BioBits

    Type

    Blog Post

    Published

    Aug. 2, 2018, 12:56 p.m.

    ...mix chemicals together in chemistry to see what happens, but there isn’t really an equivalent of a “chemistry...

21. Plasmids 101: Gram Negative and Positive Bacteria

    Type

    Blog Post

    Published

    Aug. 2, 2022, 1:15 p.m.

    ... added, it dehydrates the peptidoglycan layer, trapping the large dye complex created by the interaction...

22. Viral Vectors 101: Inverted Terminal Repeats

    Type

    Blog Post

    Published

    Oct. 19, 2023, 1:15 p.m.

    ... of research is important for downstream AAV applications.  Tips & FAQs Due to their high GC content and...

23. Cultivating Community Science at BosLab

    Type

    Blog Post

    Published

    Nov. 2, 2017, 1:35 p.m.

    ...the biotech revolution. Our lab exists in what appears to be a funky old garage, but looks can be deceiving...

24. Hot Plasmids - December 2019 - CRISPR pooled library, LipoGlo, CRISPRa, and Voltage Imaging Tools

    Type

    Blog Post

    Published

    Dec. 10, 2019, 1:58 p.m.

    ...The LipoGlo system represents a new, intriguing approach to expand our understanding of ApoB-LPs and accelerate...

25. With Our New Viral Service, We're Taking CRISPR Further!

    Type

    Blog Post

    Published

    Dec. 6, 2016, 3:30 p.m.

    ...Numbers in the large colored circles are rough approximations of the total number of CRISPR plasmids for ...

26. Choosing Your Fluorescent Proteins for Multi-Color Imaging

    Type

    Blog Post

    Published

    Oct. 9, 2014, 3 p.m.

    ...month, deciding on the best protein for a given application is a challenge. To help keep you abreast of the...

27. Plasmids 101: Transformation, Transduction, Bacterial Conjugation, and Transfection

    Type

    Blog Post

    Published

    June 25, 2019, 12:54 p.m.

    ...Scientists can also use electroporation, the application of an electrical charge to cells, to increase...

28. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

    Type

    Blog Post

    Published

    June 6, 2019, 12:41 p.m.

    ...that undergo light-induced dimerization. Upon application of blue light, iLID undergoes a conformational...

29. 15 Years of Addgene: The Top 15 Plasmids

    Type

    Blog Post

    Published

    Jan. 8, 2019, 1:54 p.m.

    ...cell types so it is useful in a wide range of applications. This plasmid was the top requested plasmid ...

30. A Quick Guide to a Career in Software Product Management

    Type

    Blog Post

    Published

    Nov. 24, 2020, 2:15 p.m.

    ...realize that the bench isn’t where they will be happiest. What is software product management, and how ...