GCE4All: Making Genetic Code Expansion Accessible
Type
Blog Post
Published
June 15, 2023, 1:15 p.m.
...technology or as a therapeutic.
A (very) brief history
GCE came onto the synthetic biology scene in 1989...be individually optimized for each of the three factors: the ncAA, the tRNA, and the tRNA synthetases. ...balance can be extremely tricky to find: each of the factors can negatively impact both translation and fidelity...complicated.”
And Ryan Mehl would know. He’s the director of GCE4All, an NIH-funded center located at Oregon... V. W. (2021). Genetic Code Expansion: A Brief History and Perspective. Biochemistry, 60(46), 3455–3469...