We narrowed to 804 results for: cha
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TypeBlog PostPublishedOct. 31, 2019, 1:06 p.m....gills. It attaches there until they mature and changes sex from male to female. Then, it detaches from...16191624. PubMed Central PMCID: PMC1559948. Brusca, Richard C., and Matthew R. Gilligan. "Tongue replacement...
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X-CHIME: Context Dependent Germline Knockout in Immune Cells
TypeBlog PostPublishedJan. 16, 2024, 6:13 p.m....knockout mice, which is time-consuming, as it only changes one gene at a time. CRISPR-based systems enable...power of these systems to investigate in vivo mechanisms, we targeted two phosphatases, PTPN1 and PTPN2... -
Tag Your Favorite Yeast Genes with Ease
TypeBlog PostPublishedNov. 19, 2013, 2:37 p.m....yeast developed by Dr. Pringle’s former lab at UNC Chapel Hill. Bähler et al.(2) describe a modular collection... McKenzie A 3rd, Demarini DJ, Shah NG, Wach A, Brachat A, Philippsen P, Pringle JR. Yeast. 1998 Jul;14... -
Addgene is Expanding Our Viral Vector Service!
TypeBlog PostPublishedOct. 15, 2024, 1:15 p.m....and you will be notified via email. There is no charge for the request process. Ordering If your request...until you have placed your order. You will only be charged once you have added the prep to your cart and checked... -
Supporting Rare Disease Research with BeHeard 2017
TypeBlog PostPublishedJuly 20, 2017, 2:30 p.m.... cause spinal muscular atrophy, the molecular mechanisms behind the disease are unclear. Dr. Di Schiavi... Dr. Di Schiavi will use Addgene plasmids to characterize smn1 interactions with other genes. He will ... -
Scientific Sharing in the Time of COVID-19: Databases and Resources
TypeBlog PostPublishedMay 12, 2020, 1:15 p.m....otherwise not be able to work on through normal mechanisms. It will take the full breadth of our research...comprehensive list). #coronavirus #SARSCoV2 #Covid19researchA thread ⬇️⬇️⬇️ — Addgene (@Addgene) April 15... -
What's New in CRISPR - March 2020
TypeBlog PostPublishedMarch 10, 2020, 1:15 p.m....that controls repression of gene expression in Saccharomyces cerevisiae. The system consists of dCas9, the...several weeks to delete or deplete individual genes. Michael Laub’s lab developed a CRISPRi system to downregulate... -
Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot
TypeBlog PostPublishedDec. 5, 2019, 1:49 p.m....homepage recently, you probably noticed some big changes to our site (if you haven’t, go check it out!)....happy and inspired to tackle your next science challenge. If you have any feedback, please contact us and... -
A Better Way to Get Customer Support: The Help Center
TypeBlog PostPublishedDec. 10, 2015, 3:30 p.m..... With your busy schedule, you may not have the chance to stop what you’re doing and make a phone call... Bryan Archambault... -
pSiM24: Simplifying Plant Genetic Engineering
TypeBlog PostPublishedSept. 29, 2015, 2:30 p.m....modified with duplicated enhancer domains and characterized in studies of tobacco, Arabidopsis, and corn...paper at Addgene. Other relevant blog posts 3 Challenges in Plant Synthetic Biology Quick, Versatile Plant... -
Mapping the 4D nucleome with CRISPR/Cas9
TypeBlog PostPublishedAug. 11, 2015, 2:30 p.m....inter- and intrachromosomal dynamics, and how they change in response to the cell cycle or other stimuli....intrachromosomal loci, a major benchmark in characterizing the 4D nucleome. Future modifications and applications... -
London Calling - Addgene’s New Europe Office in London
TypeBlog PostPublishedJune 10, 2014, 3:20 p.m....States - Cambridge, MA to be exact. Today, that changes. Today, Addgene launches a brand new Europe office...scientists together from all over the world to exchange research materials in an easy way. She has a passion... -
New Viral Vectors - Fall 2024
TypeBlog PostPublishedOct. 3, 2024, 1:15 p.m....types of the basal ganglia. They work via newly-characterized enhancers that enable a whole host of (awesome...AAV-GfaABC1D-Cre-4x6T AAV5 Recombinases Stanley Thomas Carmichael New viral prep pAAV-EF1a-fDIO-Cre AAV5 Recombinases... -
Addgene's a Nonprofit? Nonprofit Awareness Day 2017
TypeBlog PostPublishedJune 5, 2017, 3:19 p.m.... Mary, Max, Maya, Meghan, Melina, Meron, Michael Lo., Michael Le., Michel, Michelle, Morgan, Natashia,... -
SunTag and Fluorescent Imaging
TypeBlog PostPublishedMarch 28, 2017, 2:30 p.m....localized, and how its localization and expression may change across various conditions. However, this system...Improved brightness and signal-to-noise ratio Less chance of phototoxicity Reduced photobleaching Simplified... -
Plasmids 101: Positive and Negative Selection for Plasmid Cloning
TypeBlog PostPublishedAug. 22, 2019, 12:43 p.m.... interest by taking advantage of bacterial characteristics such as prototrophy, the ability to synthetize...used for negative selection on 5% sucrose plates. Exchange of the sacB gene for the gene of interest allows... -
Viral Vectors 101: Parts of the AAV Packaging Plasmid
TypeBlog PostPublishedDec. 3, 2020, 2:15 p.m....Introducing changes and/or short peptides sequences into these variable loops is one method for changing a capsid... -
CRISPR 101: Drug discovery and CRISPR
TypeBlog PostPublishedMay 4, 2023, 1 p.m....model can be generated, and drugs screened for a change in pathology. If the disease pathology is complex...Target identification Not all diseases are fully characterized or have a simple pathology. In these cases, ... -
Five Questions to Ask If You're Deciding Between a Master's or PhD Program
TypeBlog PostPublishedFeb. 16, 2021, 2:15 p.m....growth is possible even if your job title doesn’t change. Master’s level training can prepare you to present... career with a master’s. While it's possible to change fields of research with a PhD, a master’s is less... -
Oh, The Places You Can Go: Careers in Science Communication - Product Development
TypeBlog PostPublishedOct. 18, 2017, 1 p.m.... a job and I stumbled upon eScience by luck, by chance, by complete happenstance. It was on Indeed or ...company. And make sure to subscribe to the Career Channel of the blog so you don’t miss the future posts ...