We narrowed to 663 results for: Mal

1. New and Upcoming Viral Vectors - June 2019

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   Blog Post

   Published

   June 18, 2019, 1:15 p.m.

   ...chemogenetic AAV for activating and inhibiting neurons. Minimally-tagged DREADD AAV from the Richie lab are especially...

2. Fluorescent Protein Travel Awards - Protein Variants, a Serotonin Sensor, and an Artificial Leaf Replica System

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   Blog Post

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   June 4, 2019, 1:02 p.m.

   ... the variants to eGFP followed by an internal ribosomal entry site and mCherry. If a variant has wild-...

3. The Crispr Babies Saga Shows the Need for Action, Not More Delays

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   Blog Post

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   Dec. 20, 2018, 1:15 p.m.

   ...practice: computer simulations, in vitro research, animal models, and several stages of human clinical trials...

4. Addgene-Seeding Labs plasmid grant round 3: microbial drug resistance and biofilms, antidiabetic plant components, visualizing brain injury - and a glowing robot fish

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   Blog Post

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   Nov. 27, 2018, 2 p.m.

   ...strain. The sensor will be transported inside a small 3D printed robot that will “swim” in the river, ...

5. Networking Follow-up: I Met a Person. Now What?

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   Blog Post

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   Jan. 12, 2021, 2:15 p.m.

   ... delighted to be reconnected.  Science can be a small community and you will come across your contacts...

6. Predicting Adverse Reactions to Monoclonal Antibody Drugs

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   Blog Post

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   Feb. 13, 2024, 2:15 p.m.

   ...of a middle ground between 2D assays and in vivo animal models. In these cases, they are designed to mimic...

7. Trading Spaces - Visiting Scientist Edition

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   Blog Post

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   Aug. 22, 2023, 1 p.m.

   ...that you would like to visit, if you don’t have a formal connection, you can just reach out to start the...

8. Multiplexed Overexpression of Regulatory Factors (MORF) collection

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   Blog Post

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   March 30, 2023, 1:15 p.m.

   ...expression, turning transcription on and off by binding proximal to their target genes. Since gene expression patterns...

9. Using CRISPR/Cas9 to Edit Disease Out of the Genome

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   Blog Post

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   June 23, 2022, 1:15 p.m.

   ...that CRISPR/Cas9 could be used to edit several autosomal-dominant mutations that have been connected to...

10. Reagent Repositories Are Speeding up Science During the Pandemic

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    Blog Post

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    Aug. 4, 2020, 1:15 p.m.

    ... Subbarao K, Roberts A (2006) Is there an ideal animal model for SARS? Trends in Microbiology 14:299–303...

11. Scientists Map the SARS-CoV-2-Human Interaction Network

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    Blog Post

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    April 9, 2020, 1:15 p.m.

    ...everything we can to help find a cure -- and quickly. Normally drug discovery is a process that would take years...

12. R Bodies: Membrane-Rupturing Microscopic Tools

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    Blog Post

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    April 14, 2016, 2:30 p.m.

    ...to find R body mutants that couldn’t extend at a normal pH and later realized that these mutations clustered...

13. From Lab Bench to Leadership: Transitioning into Management as a PhD

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    Blog Post

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    Jan. 21, 2025, 2:15 p.m.

    ...to my mentors, as they encouraged me to explore small-scale opportunities where I could make mistakes ...

14. Flow Cytometry Readouts: Yes, No, and Everything in Between

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    Blog Post

    Published

    Aug. 20, 2024, 1:15 p.m.

    ...still continue gating populations of interest with normal gates, just based on a histogram plot instead of...

15. Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies

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    Blog Post

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    July 28, 2017, 1:30 p.m.

    ...your docking site is located). This amounts to a small difference of two or three weeks. 3. How would you...

16. Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer

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    Blog Post

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    July 6, 2017, 1:59 p.m.

    ...starvation on cancer therapy. Findings in previous animal studies suggested that fasting has a positive effect...

17. Multiplex Genome Editing with CRISPR-Cpf1

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    Blog Post

    Published

    May 9, 2017, 2:12 p.m.

    ...bulk from crRNA expression plasmids resulting in smaller, more streamlined vectors which are easier to use...

18. A Novice's Perspective on Neuroscience - SfN2017

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    Blog Post

    Published

    Dec. 15, 2017, 2:07 p.m.

    ...delivering genes to many different cell types with minimal immunological effects. AAVs are used in experiments...

19. Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification

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    Blog Post

    Published

    Nov. 19, 2019, 2:08 p.m.

    ...light is in an open conformation.  Nanobodies are a small (~15 kDa), single monomeric variable heavy chain...

20. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

    Type

    Blog Post

    Published

    June 6, 2019, 12:41 p.m.

    ... genes for noninvasive imaging of microbes in mammalian hosts Article contributed by Lukas Morgan  Listen...