We narrowed to 847 results for: CAL;
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TypeBlog PostPublishedJune 24, 2020, 5:45 p.m....sequences. Non-editing CRISPR applications direct catalytically dead dCas9 fused to a variety of epigenetic ...from Addgene. For most of these constructs, catalytically dead modifiers are also available as controls...Resources on the Addgene Blog Cas9 Activators: A Practical Guide CRISPR Between the Genes: How to Experiment...
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Viral Vectors 101: AAV Variables That Matter
TypeBlog PostPublishedJune 1, 2023, 1:15 p.m....Using AAV vectors in complex biological systems can be tricky at best, and downright infuriating at worst...promoter in vivo. Molecular Therapy - Methods & Clinical Development, 3, 16062. https://doi.org/10.1038... Expression specificity of GFAP transgenes. Neurochemical Research, 29(11 SPEC. ISS.), 2075–2093. https... -
Plasmids 101: Using Transposons in the Lab
TypeBlog PostPublishedJuly 6, 2021, 1:28 p.m....transposition: Class I TEs, also called retrotransposons, and Class II TEs, also called DNA transposons. DNA transposons...in a genome. But there is a type of mobile DNA, called a transposon, that’s a bit hyperactive and likes... -
Overwhelmed? Take a Break With Our 5 Favorite Science Comics
TypeBlog PostPublishedDec. 5, 2013, 3:27 p.m.... a laughter program significantly decreased immunological markers of stress in adolescents. It also put...great use of your time even as that lab bench is calling, let me share my top five new favorite science ... -
Celebrating the 2024 Nobel Prize in Chemistry
TypeBlog PostPublishedOct. 17, 2024, 1:15 p.m....understanding of how protein folding works and creating biological tools not found in nature. Dr. Baker’s team was...was not based on any existing protein structures, called Top7. Figure 1: Top7 receives the Nobel ... -
Bringing Renewable Energy to Addgene
TypeBlog PostPublishedAug. 27, 2019, 1:08 p.m....of an “electricity aggregation program” for all local households and businesses. Electricity aggregation... energy expenditure here at Addgene. These are critical systems that cannot be removed or substantially... -
Celebrating One Million Plasmids Shared!
TypeBlog PostPublishedSept. 25, 2018, 2:39 p.m....September 13, 2018 This massive scale reagent sharing led us to calculate how much time we have saved researchers... -
Congratulations, Deck The Lab winners!
TypeBlog PostPublishedJan. 14, 2021, 1:30 p.m....wear a mask,↔️social distance, 💓show gratitude,☎️ call up an old friend. Remind them you care!#thanks #...viruses. Final tree with the complete #MicrobeAdventCalendar ornament set (plus more!) It features archaea... -
New Viral Vectors - Summer 2024
TypeBlog PostPublishedJuly 9, 2024, 1:15 p.m....preparations of several variants of a new optogenetic tool called PdCO, deposited by the Yizhar lab. Addgene is now...preparations of several variants of a new optogenetic tool called PdCO. This is an "optoGPCR" (coupled to Go, so... -
New Viral Vectors - Spring 2025
TypeBlog PostPublishedApril 29, 2025, 1:30 p.m....E6 regulatory element, which targets it to VIP cortical interneurons. Take a look to see if these new ...Wilson New serotype AAVrg = AAV retrograde (also called AAV2-retro) Looking for more viral vectors? Browse... -
Visualizing Your Plasmid Request Data
TypeBlog PostPublishedApril 11, 2023, 4 p.m....with most reagents sent, and the most recent full calendar year When the website is launched, it will show...Amsterdam). He develops, characterizes, and uses genetically encoded fluorescent probes. You can follow him... -
Kwabena Duedu on Public Health, Biofuels, and Doing Science in Ghana
TypeBlog PostPublishedDec. 20, 2016, 3:30 p.m....:26 : Kwabena's plans for work in Ghana - Using local biomass "waste" to produce biofuels. 23:27 - 25:...foods. 44:15 - 46:34 : Kwabena's goal to build biological science opportunities in Ghana. 46:35 - end :... -
Editor's Choice, October 2016
TypeBlog PostPublishedNov. 4, 2016, 2:30 p.m....finishing up their time in the PhD Program in Biological and Biomedical Sciences at Harvard University. Ben and... -
Ghanaian Researchers to Receive Plasmid Awards from Addgene and Seeding Labs
TypeBlog PostPublishedJune 15, 2016, 1:30 p.m....acquires through Addgene to produce molecular biological tools like Taq polymerase, T7 polymerase, EcoRI...scientists to continue to do excellent work in the biological sciences. Future awardees Now that this first... -
The Developmental Studies Hybridoma Bank: Over 25 Years of Antibody Sharing
TypeBlog PostPublishedMarch 10, 2015, 2:25 p.m....the antigen of interest. The immortalized cells, called hybridomas, are individually isolated and expanded...repositories provide standardized quality-control and technical support to the community. Thanks to Our Guest ... -
Introducing an All-in-One CRISPR/Cas9 Vector System for Multiplex Genome Engineering
TypeBlog PostPublishedNov. 12, 2014, 3:54 p.m....Hiroshima University. “However, there had been no systematically established way of making an all-in-one vector...Activity Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening ... -
What's New in CRISPR - May 2019
TypeBlog PostPublishedMay 28, 2019, 12:49 p.m....plasmids available at Addgene. We will still periodically focus on specific CRISPR plasmid tools more ...E. coli, the Chong Zhang lab developed a genome-scale CRISPR inhibition pooled library (~60,000 gRNAs)... -
Making Career Development an Integral Part of the Science Training System
TypeBlog PostPublishedFeb. 25, 2021, 2:15 p.m....Cynthia Fuhrmann at University of Massachusetts Medical School. It has been supported by a Steering Committee...A grant from the National Institute of General Medical Sciences (NIGMS) will support the development and... -
How Do I Place an Addgene Order Using a PO Number?
TypeBlog PostPublishedFeb. 27, 2020, 2:15 p.m.... Support Specialists here at Addgene. If you’ve called our customer service line or sent an email to help...plasmids, store your plasmids or viral items, technical support, and more. ... -
Keeping Up With CRISPR/Cas9
TypeBlog PostPublishedMarch 11, 2014, 5:55 p.m.... by even splashier news: Jiahao Sha of Nanjing Medical University had successfully used the CRISPR/Cas9... Times feature when he said, “All of this has basically happened in a year. It’s incredible.” Looking...