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TypeBlog PostPublishedOct. 19, 2023, 1:15 p.m.... D. V. (2023). AAV- based vector improvements unrelated to capsid protein modification. Front Med, 10,...
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Early Career Researcher Toolbox: Free Tools for Science Writing
TypeBlog PostPublishedApril 28, 2021, 1:15 p.m.... finding and organizing papers, check out this related blog post: Early Career Researcher Toolbox: Finding... -
Components of CRISPR/Cas9
TypeBlog PostPublishedFeb. 2, 2016, 5 p.m....use a non-specific endonuclease (Cas9 or closely related Cpf1) to cut the genome and a small RNA (gRNA) ... -
Management for Scientists: Delegating is Key
TypeBlog PostPublishedFeb. 20, 2015, 8:30 p.m....and this is a recipe for bad outcomes. Clearly articulate the desired outcomes. Begin with the end in mind... -
Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog PostPublishedMarch 17, 2020, 1:32 p.m....better base editors with the help of phages! The latest ABE from the Liu lab is ABE7.10 which contains ... -
Communicating Your Science With Help From ComSciCon
TypeBlog PostPublishedJuly 19, 2018, 1:12 p.m.... it. In the lab, it might mean persuasively articulating why the results you've measured should change... -
Plasmids 101: Transformation, Transduction, Bacterial Conjugation, and Transfection
TypeBlog PostPublishedJune 25, 2019, 12:54 p.m.... they can be made competent through chemical manipulation in the lab. This is commonly done using calcium... -
AAV Q&A with Tim Miles
TypeBlog PostPublishedMay 17, 2022, 1:15 p.m....elusive. There has also been a lot of effort in immunomodulation or immune suppression to allow AAV re-administration... -
Antibodies 101: Buffers, Storage, and Conjugates
TypeBlog PostPublishedFeb. 1, 2022, 2:15 p.m....can be very helpful if you're trying to find a relatively rare protein in an experiment with many proteins... -
Enabling Precision Functional Genomics with the Target Accelerator Plasmid Collection
TypeBlog PostPublishedMay 11, 2017, 2:30 p.m...., in principle, these experiments could find correlations between variants in a gene of poorly classified... -
Clear and Accessible Writing
TypeBlog PostPublishedFeb. 15, 2024, 2:15 p.m.... will help your scientific writing across all platforms, from posters to papers. We hope this helps, ... -
Viral Vectors 101: Viral Vector Elements
TypeBlog PostPublishedJuly 25, 2023, 1 p.m....helps with virion assembly and particle release from late endosomes when AAV is trafficked. Rep and cap mediate... -
How Addgene Creates Content
TypeBlog PostPublishedNov. 17, 2022, 2:15 p.m....researchers in creating and sharing knowledge, related to the types of materials we help distribute and... -
Top Requested Lentivirus and AAV of 2016
TypeBlog PostPublishedJan. 6, 2017, 3:56 p.m....CRISPR tools, though we do provide a few non-CRISPR related viral preps. Cas9 is the headliner of most CRISPR... -
A Novice's Perspective on Neuroscience - SfN2017
TypeBlog PostPublishedDec. 15, 2017, 2:07 p.m....a talk about the different parts of the brain stimulated by stories. In retrospect, I should have expected... -
How to Keep a Lab Notebook for Bioinformatic Analyses
TypeBlog PostPublishedJune 2, 2016, 2:30 p.m....TextWrangler to record the following, which are later printed for my physical lab notebook, along with... -
Pooled CRISPR Libraries Offer Genome-Wide Control for Large-Scale Functional Screens
TypeBlog PostPublishedFeb. 24, 2015, 7:50 p.m....theoretical limit on the number of genes that can be manipulated at one time. Weissman’s group has made standard... -
Hot Plasmids - March 2020 - base editors, GEVI, MoClo, and optogenetics
TypeBlog PostPublishedMarch 3, 2020, 2:15 p.m....and further studies of optical neural circuit manipulations when combined with existing green-fluorescent... -
RANbodies: Reporter Nanobody Fusions
TypeBlog PostPublishedApril 10, 2018, 12:56 p.m....individual labs to complete. The nanobody based RANbody platform from the Sanes Lab overcomes this limitation and... -
Oh, The Places You Can Go: Careers in Science Communication - Writing for a Research Institute
TypeBlog PostPublishedFeb. 2, 2018, 3:20 p.m....certificate in Strategic Communications and Public Relations at the University of Washington and the connections...