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...influence (non-homologous end joining, or NHEJ), in approximately one percent of cases, the stem cell will seek...

...risk of dangerous DNA damage. If the way DNA is wrapped around histones changes, then gene expression can...

...those flames about? Flame logo: The flame that appears beside some of Addgene’s plasmids is an indication...

...negatives – As with any experiment, the use of appropriate controls, multiple replicates and several cell...

...expertise available in your lab or organization, and approvals from the organization overseeing your work. Good...

...substantial. It's estimated that genetic engineering as applied to products on the domestic market generates $300...

... couple of weeks now”. I had no idea this was happening even though I met with X on a weekly basis! The...

...suspected, we proceed to de novo assembly of the unmapped reads, employing our bioinformatics software to...

...but have run into a wall trying to study it? It happens. Is it an evolutionarily conserved gene? Can you...

...Addressing the potential use of RESCUE in therapeutic applications, the authors tested various dRanCas13b truncations...

...deciding on which one to use will depend on your application (see table below). The antibodies available for...

...this information can be cited, tracked, and appropriately credited, broadening the knowledge base of AAV...

...the same drawbacks to each reagent type, so this approach is not suitable for all antibodies. Detergents...

...rather a glass powder slurry that has a milk-like appearance. To make DNA stick to the glass particles in ...

...protocol prior to transformation (Figure 1). As this approach requires no special reagents or purification kits...

...placed in an Agrobacterium solution and a vacuum is applied with a vacuum bell or desiccator. Successful infiltration...

...Often times, a gene gets its name based on what happens to an organism when a gene/protein is depleted ...

...question probably comes to mind: can CRISPR be applied to fix the defective base precisely? Until 2016...

...to dramatically increase the number of CRISPR applications. The first non-Cas9 CRISPR protein adapted for...

...like viral preps and libraries were kept at the appropriate temperature for the duration of their journey...