Viral Vectors 101: Systemic Capsids
Type
Blog Post
Published
Oct. 12, 2023, 1:15 p.m.
...Systemic capsids packaging Cre-dependent transgenes can also be paired with Cre-expressing transgenic mouse..., N., Pasca, S. P., & Gradinaru, V. (2016). Cre-dependent selection yields AAV variants for widespread... B. E., & Gradinaru, V. (2020). Multiplexed Cre-dependent selection yields systemic AAVs for targeting...systemic capsid for an individual application is dependent on a number of factors, including species, strain... as well as the type of transgene delivered: fluorescent proteins, optogenetic sensors, CRISPR elements...model organisms
Tropism and efficacy can vary depending on species. LY6A and LY6C1 do not have known homologs...