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Showing: 251 - 300 of 812 results

  1. Transferable Skills Guide: Creativity

    Type
    Blog Post
    Published
    Jan. 18, 2022, 2:15 p.m.
    ... tangible and applicable to your situation.   Thinking Outside the Box: Team Approaches At some point ...required to develop new projects and test novel approaches, a necessary skill set for any scientist. In ...lab   Thinking Outside the Box: Individual Approaches Whether it’s finding the source of contamination...creative skills you have developed in the lab can be applied anywhere! References and Resources References ...

  2. Plasmids 101: Plasmid Incompatibility

    Type
    Blog Post
    Published
    March 31, 2020, 1:15 p.m.
    ...In this Plasmids 101 post, we’ll cover why this happens, how it might affect your work, and how understanding...rely on chance (or random diffusion) to make this happen.  There are several different versions of the plasmid...way to bacterial cloning glory, scientists have applied these concepts to deal with the more sinister plasmids...pestis using plasmid incompatibility. Letters in Applied Microbiology 47:235–240 . https://doi.org/10.1111...Bacterial plasmid partition machinery: a minimalist approach to survival. Current Opinion in Structural Biology...

  3. Lab to Office Culture Shock

    Type
    Blog Post
    Published
    Feb. 5, 2019, 1:04 p.m.
    ...move from lab to office will likely happen eventually. If you approach that transition dreading the change... scientist position at Addgene, the skeptical applicant asked if she would partake in “critical thinking...thinking” in the position to which she was applying. I probably did not respond to her question as well then...adjustment period will be that much longer. If you approach the transition embracing the opportunity for growth...

  4. Transferable Skills Guide: Career Planning Resources

    Type
    Blog Post
    Published
    Nov. 14, 2017, 2 p.m.
    ...connection you made at the job fair when you formally apply for the position. This post on Business Insider ...re likely to find current job openings. A good approach is to do this first for companies at which you...connection. That way, once you’ve identified an appropriate job opening, you can send your contact an email...the assistance of recruiters for identifying appropriate job candidates. If you do receive such a call...those relationships. Then when you are ready to apply for your dream job, you’ll be in the best possible...

  5. Tips for CRISPR Gene Editing in Mice

    Type
    Blog Post
    Published
    June 28, 2016, 10:59 a.m.
    ...contains overlapping 5′ and 3′ EGFP fragments under the ubiquitous CAG promoter. The approximately 500 bp...website invites you to input the target region (approximately 500bp is best) and select the organism. It will...different types of gRNA design software. When you are happy with your selection, ordering the sgRNA is simple...process, you should first develop primers to the approximately 500 base pair sequence surrounding your gRNA...

  6. Tips for Using FRET in Your Experiments

    Type
    Blog Post
    Published
    Nov. 5, 2014, 3:41 p.m.
    ...exist in the real world and corrective approaches and appropriate controls are required to make this method... this technique has revolutionised the way we apprehend molecular complexes and is still a very useful...experiment. You can then choose the most efficient approach for your own system. The simplest and the most...14. Zimmermann T,  Terjung S. FRET Basics and Applications: An EAMNET Teaching Module http://www.embl.de...

  7. CRISPR 101: Homology Directed Repair

    Type
    Blog Post
    Published
    Jan. 26, 2023, 2:15 p.m.
    ...one of two ways - each junction resolution could happen on the crossing strand (horizontally at the purple...strand. While this pathway may not be immediately applicable in DSB-induced genome engineering, it has biological...that can be harnessed by researchers for many applications. Your favorite Cas enzyme, a guide RNA to your...Mouse Geneticist's practical guide to CRISPR applications. Singh P, et al. Genetics 114.169771; (2014)... PubMed. Optimization of Genome Engineering Approaches with the CRISPR/Cas9 System. Li, K et al. PLoS...

  8. Hot Biosensors 2022: Year-End Roundup

    Type
    Blog Post
    Published
    Dec. 6, 2022, 2:15 p.m.
    ...getting dark and wintry with the end of year approaching. We’re always looking for something to brighten...They generated variants optimized for different applications (v82 has higher affinity for glutamate but slower... in the fluorescent properties, pYtags are an appealing tool for monitoring RTK signaling.  Figure 4:...lower binding affinities to broaden the range of applications. Image reproduced from Torres Cabán et al. 2022...screening platform developed here is also a promising approach for developing sensors for other targets. Figure...

  9. Transferable Skills Guide: Conflict Resolution

    Type
    Blog Post
    Published
    Jan. 4, 2022, 2:15 p.m.
    ...sell them. Types of Conflict Before explaining my approach to conflict resolution, it’s important to recognize...day-to-day operations and keeping our customers happy, but inevitably there will be gray areas that either...you can help everyone walk away from a conflict happy, feeling they each got enough of what they wanted...Thomas Kilmann Conflict Model describes 5 basic approaches to conflict resolution based on various levels...yourself gravitating most frequently towards these approaches, you may need to put more conscious effort into...

  10. Viral Vectors 101: Integrase-Deficient Lentiviral Vectors

    Type
    Blog Post
    Published
    May 13, 2025, 1:15 p.m.
    ...decades. Widely used across various research applications, they have become indispensable tools for manipulating...-lasting changes in cells. However, for some applications, integration might be considered a double-edged... certain types of clinical or basic research applications. Considerations for IDLV use If you’re reading...Integrase-defective lentiviral vectors: progress and applications. Gene Therapy, 17(2), 150–157. https://doi.org...lentiviral vector: prospects for safe clinical applications. PeerJ, 10, e13704. https://doi.org/10.7717/...

  11. Plasmids 101: Biotinylation

    Type
    Blog Post
    Published
    Nov. 15, 2018, 1:50 p.m.
    ...molecular biology applications for biotin and avidin. A short list of some other common applications and links...downstream application. Biotin labelled oligonucleotides can be used in a multitude of applications including... feng, Liu, N. hua, Shu, L. yuan, & Sun, H. “Application of avidin-biotin technology to improve cell adhesion...

  12. 10 Steps to a Perfect Science Talk

    Type
    Blog Post
    Published
    Aug. 23, 2016, 2:30 p.m.
    ... talks and how to make them serve you well. The happy byproduct might just be a career opportunity. The...non-academic settings. Many of these guidelines will apply to any type of science presentation, but, for more...and venue before tailoring each presentation appropriately.  Find out who will be listening.  Are they ...goal is to get the listeners to be thinking “What happens next?”  Describe how you pushed to a solution or... use no notes and can concentrate on delivery, rapport with the audience, and their own excitement about...

  13. Plasmids 101: Gibson Assembly and Other Long-Homology Based Cloning Methods

    Type
    Blog Post
    Published
    March 1, 2016, 3:30 p.m.
    ...ways to clone DNA fragments which have provided appealing alternatives to restriction enzyme cloning. These... amplification with primers that contain the appropriate homologous sequences. NEB recommends an overlap...sequences remaining in the final product. The long overlapping region between fragments also better ensures ... of the fragments as compared to the smaller overlapping sequences left with a restriction digest. A study...cloning kits available which are all based on long-overlapping regions, have no requirements for restriction...

  14. Introducing the Addgene Antibodies 101 eBook!

    Type
    Blog Post
    Published
    Oct. 29, 2024, 1:15 p.m.
    ...resource for anyone looking to use antibody-based applications in their research.  Like all our eBooks, the...through the process. If you’re confident in your application and protocols, but can’t quite seem to find an...for Your Experiment.” Whatever your antibody application question, the Antibody 101 eBook is a great place....org with any thoughts, questions, or feedback. Happy reading! ...

  15. How to Design Your gRNA for CRISPR Genome Editing

    Type
    Blog Post
    Published
    Sept. 24, 2020, 1:15 p.m.
    ...blog post will discuss differences between these approaches, and provide updates on how best to design gRNAs...capture the mRNA cap, provides the most accurate mapping (Radzisheuskaya et al., 2016). In this case, location...location and sequence are of approximately equal importance in design – an optimized sequence will do ... using knockout or transcriptional modulation approaches. Avoiding off-target effects The off-target ...fully predict which sites will and will not show appreciable levels of modification. Whole-genome sequencing...

  16. Generating Mouse Models Using CRISPR/Cas9

    Type
    Blog Post
    Published
    July 12, 2016, 2:30 p.m.
    ...it got “dirty”, with multiple sequence traces overlapping each other! When the count was done, 75% of the...but not least, when using CRISPR, remember to appreciate the fact that it was first discovered in an obscure... with Biogen and is particularly interested in applying CRISPR for mouse genome editing.     Haoyi Wang...interested in using CRISPR to develop therapeutic applications that better human health.     References Cong...Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches. Sci Rep 8: . https://doi.org/10.1038/s41598-...

  17. 2018 #DeckTheLab Contest Winners

    Type
    Blog Post
    Published
    Jan. 15, 2019, 2:19 p.m.
    ...from Nika Heijmans stood out to the Addgenies. Happy holidays!🎄☃️ More #agarart from our lab @SILS_UvA...display @Micropia! #SciArt #MerryChristmas #happyholidays2018 #DeckTheLab @Addgene @joachimgoedhart @SAbiega...recycled lab materials into holiday decorations. We appreciated the creative uses of old posters, pipette tip...to New York City. Check out their video below. Happy Holidays from the @SikoraLab! This year, @BordeauxFoSho...

  18. Plasmid Grant to Aid Cervical Cancer Screening in Ghana

    Type
    Blog Post
    Published
    Nov. 8, 2016, 3:30 p.m.
    ...expected when we originally sent out the call for applications. Cervical cancer screening in Ghana Gladys is...Papillomavirus (HPV). As Gladys wrote in her application, “Cervical Cancer is the leading cause of cancer...detection, treatment, and management. We are incredibly happy to hear that Gladys will be using plasmids in a ...Seeding Labs Plasmid Grant to a third round of applicants at the start of 2017 and would like to thank ...

  19. Inntags: Innovative Protein Epitope Tagging

    Type
    Blog Post
    Published
    Nov. 10, 2015, 3:30 p.m.
    ...immunoprecipitation applications, but none of the traditional tags were suitable for both applications. To prove...These tags are easy to use in multiple common applications. Due to their limited effects on native protein...particularly in single-molecule or high-throughput applications. Perhaps IT5 and IT6 will even replace our older...

  20. A Conference By Postdocs For Postdocs: Future of Research

    Type
    Blog Post
    Published
    Sept. 2, 2014, 3:05 p.m.
    ... recent discussions of this apparently worsening crisis recently appeared in eLife: "A Fair Deal for PhD...news and updates. Scientists must do science to be happy. What do we have to change to ensure that all scientists..., there are some easy ways to get started. I am happy to work with any group of trainees interested in...

  21. With an Eye Towards the Future, We Look Back at the March for Science

    Type
    Blog Post
    Published
    Oct. 24, 2017, 1:54 p.m.
    ... is supposed to be impartial. The best science happens when scientists have 1) the courage to make mistakes...degree. It was a great, positive event that I hope happens again. Nicholas Thompson is a PhD Candidate studying...tirelessly in the lab where the groundbreaking research happens, sometimes forgetting how to engage with friends...galilei-dialogues-concerning-two-new-sciences). This is the approach policy makers take in abusing climate science ...defund science and stay silent. I was overwhelmingly happy to see so many others come out who feel the same...

  22. Fluorescent Proteins 101: Monitoring Cell Mobility Using Fluorescent Proteins

    Type
    Blog Post
    Published
    Aug. 15, 2017, 1:24 p.m.
    ...through an electric field to deflect them into appropriate containers. The machine is useful for distinguishing...on in vitro studies where it was difficult to apprehend the key role of specialized cell types and organs...Good two-photon probes when using a standard Ti:Sapphire Laser include: Blue-green fluorescent proteins...this requires other lasers than the standard Ti:Sapphire laser. It is also important to finely tune the...creation of mouse lines that can be used in fate mapping experiments. Immune response dynamics are much ...

  23. Special Delivery: Fluorophore Targeting for FRET Studies

    Type
    Blog Post
    Published
    July 19, 2016, 2:30 p.m.
    ...cellular impediments. FRET has been used in many applications, including drug discovery by big pharma (i.e...innovation, valuable commodities in any NIH grant application! Using FRET, you may gain a new structural understanding...experiments. Donor Acceptor Tag R0 (Å)a Range (Å)b Applications CFP   Lumio Green Tc: CCPGCC 50 40-72 Intact...discovery–a review of theoretical aspects and recent applications." Current Chemical Genomics and Translational...Saraheimo, Satu, et al. "Time-Resolved FRET-Based Approach for Antibody Detection–A New Serodiagnostic Concept...

  24. Science as Art

    Type
    Blog Post
    Published
    March 2, 2015, 3:13 p.m.
    ... a serious academic subject, it is now being appreciated on an aesthetic level as well. Beautiful microscope...can be used as a way to better understand and appreciate the organism, for both scientist and non-scientist...the difference in some areas of conservation.” Appreciating science as an art form taps into an emotional...matter is seen to have increased value and is appreciated by a wider audience for more than just its biological...

  25. pSiM24: Simplifying Plant Genetic Engineering

    Type
    Blog Post
    Published
    Sept. 29, 2015, 2:30 p.m.
    ...for both transient and stable gene expression applications in plants. This smaller, easily customizable... susceptible to Agrobacterium infection. At approximately 7 kb, pSiM24 is 2 and 6 kb smaller than commercially...these properties of pSiM24 are suitable for many applications, the plasmid can also be customized due to its...only for plant engineering and biotechnology applications, but also for foundational studies of promoter...

  26. An Addgene Summer Internship

    Type
    Blog Post
    Published
    Aug. 8, 2024, 7:22 p.m.
    ... had spent most of my junior year stressed out applying for summer programs. I spent one day at Addgene...internship opportunity taking place next summer.  I applied to Addgene and began the interview process with...that my decision deadline would be extended. I appreciated how flexible Amy was, which was the impression... before stepping foot into the lab itself. I appreciated that Addgene was treating all the high school...

  27. Five Questions to Ask If You're Deciding Between a Master's or PhD Program

    Type
    Blog Post
    Published
    Feb. 16, 2021, 2:15 p.m.
    ...postings looking for PhD applicants since many will also accept applications from master’s candidates ...technical or product support specialist,” “field application scientist,” or “scientific or technical writer...Principal Scientist or Scientist I/II. Promotions don’t happen overnight though, and it might take longer to advance...

  28. Hot Plasmids - October 2022

    Type
    Blog Post
    Published
    Oct. 6, 2022, 1:15 p.m.
    ...a custom, high-throughput screening platform to apply saturating mutagenesis on 21 positions in the protein...in plasmid form. Fig. 1: Summary of the approach and outcomes of the screen for improved genetically-encoded...blot, but we are actively testing it in other applications! If you try it out in a new assay, let us know...GFP-smFP-myc expressed from Plasmid 98926. See the Applications section on the Anti-c-Myc [9E10] page for more...

  29. Oh, The Places You Can Go: Careers in Science Communication - Science Writing

    Type
    Blog Post
    Published
    Oct. 3, 2017, 12:11 p.m.
    ...defining a couple of key terms is a better approach. Also, appealing images and colors draw people in. Drawing...should be. He debated taking a position as an application support/sales representative in industry or a...illustrations for summarizing mechanisms and applications that are relevant to things IDT does. I also...

  30. Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!

    Type
    Blog Post
    Published
    July 18, 2017, 12:41 p.m.
    ...bacteria. Learn more about the different CRISPR applications in plants.     Transgenic yeast as source of...Vietnam Linh Bao Ton (center) is interested in applying gene technology to bacteria and plants. Her research... water repositories in Mexico. At Addgene we're happy to be able to support diverse groups of scientists...collaborations. Many thanks to all of the awardees, all who applied, and to Seeding Labs who helped us coordinate and...

  31. Choosing Your Perfect Empty Backbone

    Type
    Blog Post
    Published
    Aug. 19, 2014, 3:39 p.m.
    ...types of yeast expression vectors. Consider your applications and experimental design. You can create a new...shuttle vectors. You may prefer the more traditional approach of an autonomously replicating vector that carries....g. pMT-puro). Worm vectors There are several approaches to studying YGOI's function in worms. Some of...a variety of other types of vectors for most applications used to study gene function. From making transgenic...

  32. Advice for Choosing a Research Project

    Type
    Blog Post
    Published
    April 17, 2014, 2:45 p.m.
    ...project that combines an exciting new method or approach with another in a way not done before in your ... - maybe something used in astrophysics can be applied to fungal biology.” Connie Cepko advises students... technology to identify a problem, asking what approach will I take and what can I learn, learning the...importance of choosing a solid research topic and approach. At Addgene, we've heard of labs where new hires...

  33. History of CRISPR Cas - A tale of survival and evolution

    Type
    Blog Post
    Published
    Nov. 25, 2013, 10:12 p.m.
    ...proteins snip the foreign DNA into small fragments approximately 30bp in length and paste them into the CRISPR...various species and describe an assortment of applications. Despite the ubiquity of CRISPR/Cas toolkit,... multiple plasmids used for various platform applications. For more information on CRISPR/Cas, check out...for your research. Do you have a cool idea or application that involves CRISPR/Cas technology? Let us know...

  34. Viral Vectors 101: Transductions

    Type
    Blog Post
    Published
    April 30, 2024, 1:15 p.m.
    ... typical genetic cargo — the viral genome — is swapped, at least partially, for a nucleic acid cargo of...since the majority of the viral genome has been swapped for alternative genetic cargo, they can’t reproduce...viral preps available for a variety of broadly applicable and popular viral vectors. Check out our viral...should you opt to make a virus instead of just zapping your cells? That really depends on two things. ...

  35. Behind-the-scenes of the Isolation of the Thermostable IgnaviCas9 From a Yellowstone Hot Spring

    Type
    Blog Post
    Published
    Nov. 12, 2019, 2 p.m.
    ... unexplored. Using new single-cell sequencing approaches, the lab was able to eliminate the need for axenic...Quake Lab, volunteered to do the sampling and I happily agreed to accompany him to YNP the following year...a thermostable Cas9 be useful? It can enable applications where reagents must be stored at elevated temperatures...stability under harsh conditions. One example application from the publication is the removal of unwanted...

  36. The Golden Stopwatch Award: Recognizing Facilitators of Research

    Type
    Blog Post
    Published
    Sept. 5, 2019, 1:06 p.m.
    ... transfer resources (summaries, electronic MTA approval, archive of old MTAs, and more) Does your TTO ...periodically for possible new awardees, and we’re happy to share stats and strategies with tech transfer...executed between a TTO and Addgene, whose terms apply to all future deposits of materials with Addgene...executed between a TTO and Addgene, whose terms apply to all future materials requests from Addgene MTA...

  37. Safe Port in a Storm...How Addgene is Weathering the Pandemic

    Type
    Blog Post
    Published
    Sept. 17, 2020, 1:15 p.m.
    ...teamwork and initiative it took to make all this happen with 80% of the team working remotely. We’re extremely...capacity to serve the scientific community. First, we applied for the government sponsored Paycheck Protection...a miraculous grant from Fast Grants, which was approved in a matter of days because they grasped the crucial...on track to succeed at the same time. I began approaching science funding organizations to request support...

  38. Viral Genome Sequencing - A One Stop Shop for AAV Identity and Serotype Confirmation

    Type
    Blog Post
    Published
    April 23, 2020, 1:15 p.m.
    ...TA-based ligation and tagmentation preparation approaches described previously require a preliminary double...that could be used as a template for downstream applications (Berns, 1972). Using qPCR and restriction enzyme... sequencing workflow. Using this simplified approach, we sequenced over 100 AAV vector preparations...believe that this simplified sequencing and analysis approach can be easily incorporated into standard QC regimens...

  39. Antibodies 101: Avoiding the Mouse on Mouse Mess in IHC

    Type
    Blog Post
    Published
    Sept. 21, 2023, 1:15 p.m.
    ... “species on species”) immunochemistry (IHC) applications an issue? The culprits are endogenous IgGs in... same species as your primary/sample, and then applying this mixture to your tissue (Tuson, et al., 1990...After washing away unbound fragments, you can then apply your primary and secondary antibodies as normal....Partridge TA (1998). A New Blocking Method for Application of Murine Monoclonal Antibody to Mouse Tissue...

  40. Natural or synthetic? How Addgene’s dataset reveals trends in biological innovation

    Type
    Blog Post
    Published
    Nov. 8, 2018, 3:47 p.m.
    ...opportunity to study it and see what happens when technological change happens really fast,” Thompson says. To...of sequence data. A group of scientists from MIT tapped into this data to learn about trends in synthetic...have generated robust tools that have practical applications in monitoring the accidental or intentional ...

  41. Hot Plasmids June 2018 - Reverse transcriptase, nanobody, and protein-DNA interaction tools

    Type
    Blog Post
    Published
    June 27, 2018, 1:16 p.m.
    ...makes them more adaptable to a broad range of applications. Recently, the Spiess lab developed a set of...Institute focuses on proteomics: developing and applying new technologies to quantify proteins in tissues...Scientist in the group, developed a CRISPR-based approach to detect proteins that associate with specific...used to label all proteins within a radius of approximately 20 nm of a specific DNA sequence in only 1 min...

  42. The Strength of Story Telling

    Type
    Blog Post
    Published
    Dec. 19, 2017, 2 p.m.
    ...all things almost all of us are programmed to appreciate and understand. We build narratives around the...readers or listeners thus expanding the impact and appreciation for their research. Long story short, telling... to date, invite people to ask questions, be approachable. Engage with your audience and try to learn ...clear what was difficult and what was easy when appropriate. It might not be scientific to bring emotional...

  43. Addgene's Top 10 Blog Posts of 2015

    Type
    Blog Post
    Published
    Dec. 7, 2015, 6 p.m.
    ...revolution in biological research. We’re incredibly happy to see that one of our career posts has made it ..., we hope we can help all researchers achieve happiness in their careers regardless of their end goals...addgene.org. Thank you again for a fantastic year and happy reading! Top 10 blog posts of 2015 1. CRISPR 101...some common controls and why you might need them. Happy Reading!   Resources on the Addgene Blog Download...

  44. Plasmids 101: A Brief History of Plasmids and an Improved eBook!

    Type
    Blog Post
    Published
    Oct. 29, 2015, 2:30 p.m.
    ...parasites, to symbionts, to genes and the labels applied to them were vague or contradictory, owing in part...elements. At the time, the use of episome seemed appropriate, especially since the Fertility, or F-factor ...seen as an ubiquitous tool that can be diversely applied to many different experiments. Addgene was founded...Vectors" chapters, and more pictures and pro tips.  Happy reading! Learn more about the history of plasmids...

  45. Even more elegant: Single injection CRISPR/Cas9 in C. elegans

    Type
    Blog Post
    Published
    July 7, 2015, 3:36 p.m.
    ...Creating a modular, selection-based gene tagging approach Multiple features of C. elegans have made CRISPR...permission from the Genetics Society of America. Applications of this system Dickinson et al. have developed... in cell culture. In addition to CRISPR/Cas9 applications, SEC selection could replace other, more restrictive...Additional Resources on the Addgene Blog An “elegans” Approach to Better Cas9 Editing Efficiency CRISPR 101: ...

  46. New and Upcoming Viral Vectors - September 2019

    Type
    Blog Post
    Published
    Sept. 12, 2019, 1 p.m.
    .... For a single action potential, GCaMP7s is approximately twice as bright, relative to baseline fluorescence...fluorescence, as the GCaMP7f variant, and is approximately 5-fold brighter than GCaMP6s. jGCaMP7f is the fastest...inactive neurons is reduced. This variant has an approximately 12-fold increase in brightness after ~100 action...genetically-defined neuronal populations with intersectional approaches is a growing field that we aim to support by ...

  47. Fluorescent Protein Travel Awards - Protein Variants, a Serotonin Sensor, and an Artificial Leaf Replica System

    Type
    Blog Post
    Published
    June 4, 2019, 1:02 p.m.
    ...research. This year, we put out another call for applications. We had an overwhelming response and were excited...many creative uses of fluorescent proteins. We’re happy to announce the three winners of this year’s Michael...does that mean? Previous research shows that approximately 75% of all protein-coding pathogenic human variants...artificial leaf replica system. “This bottom-up approach will allow me to create a fully controllable and...

  48. DAP arrays for multiplex gene editing

    Type
    Blog Post
    Published
    July 7, 2022, 1:15 p.m.
    ...in pairing with base editing and prime editing approaches. Recently, Xue Sherry Gao’s lab at Rice University...packaged into viral vectors for potential in vivo applications or multiplex CRISPR screening.   Using tRNAs...and efficient in plasmid and viral vectors. In applications when repetitive tRNA sequences must be avoided...construct DAP array for multiplex gene editing applications, we provide detailed manual and online design...

  49. Scientists Map the SARS-CoV-2-Human Interaction Network

    Type
    Blog Post
    Published
    April 9, 2020, 1:15 p.m.
    ...millions, if not billions, of dollars, but by approaching it from a new direction, we hope to do it much...Guo, Fengbo Zhou, Paddy O’Leary (UCSF). Our approach is to discover key human proteins that can be ...therapeutics that are safe, effective, and already FDA-approved). This is a big job, but under the leadership ... half the drugs hitting these proteins are FDA-approved or in clinical trials or preclinical studies already...

  50. The Crispr Babies Saga Shows the Need for Action, Not More Delays

    Type
    Blog Post
    Published
    Dec. 20, 2018, 1:15 p.m.
    ...erupted in controversy. Briefly, there are two overlapping, valid critiques being offered of He’s work: ...public involvement, research, and consensus can happen. We just have to look to the United Kingdom’s Nuffield... technique was feasible, three separate things happened nearly simultaneously: The Wellcome Trust funded...biosecurity, and the entire 2018 saga of “what’s happening in genetics this time?” She lives with her partner...
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