We narrowed to 884 results for: ica

...non-bench research career such as law, medical/technical writing, clinical, regulatory, product development,...specialty occupation" as requiring theoretical and practical application of a body of highly specialized ...Further, this post may contain technical inaccuracies or typographical errors.  No action should be taken...18, 2017, President Trump signed a "Buy American, Hire American" Executive Order which sets broad policy... industry such as technology transfer, communications, medical writing, compliance, core facility management...received 116,224 employment based green card applications and approved 91,023 during the first 3 quarters...options discussed in this post benefit from the applicant thinking about the process early, keeping good...

...as synthesis modifications when purchasing your gRNA. Pro tip: modifications are typically incorporated...switches. Stabilizing gRNA modifications  Sugar phosphate backbone modifications The recognition sequence...phosphorothioates with 2’-O-methyl modifications, proved more stability than just one modification alone (Hendel, et al...modified) for optimal stability and efficacy.    Base modifications What is more stable than RNA? DNA! ...stabilizing modifications listed above were developed before CRISPR-Cas9, for use in applications like siRNA...oligonucleotides. Some of these synthetic modifications, specifically ones which do not contain a 5’ triphosphate...immunity itself is being studied.   Chemical RNA modifications to improve stability.   On-off switches...

...in science communication or policy, being able to communicate your work to a non-technical audience is...knowledge and applications generated from this research. At both a practical and ethical level, scientists...benefits as well as the personal, social and ethical implications of genetics. In these conversations, pgEd...training beyond the biological sciences, as well as to acquire leadership and communication experience. These...science policy and science communication A career in science communication or policy requires broad interest... in our field of interest. We often communicate in very technical and jargon-filled language in academic.... Also seek out opportunities to communicate science to non-technical audiences. Many universities or ...

...illumination on biochemical processes that are crucial in the world of biological research, medical therapy, ...components, typically a protein of interest. Fluorescent dyes and ligands vary in their chemical structure...the affinity tag they typically bind to. Stability of fluorescence: For applications that involve ranges...recruitment to receptors, indicating their agonistic nature. The potency and efficacy of these ligands can ...their product descriptions, or technical manuals. Specific applications and matching dye/ligand choices... in biological research. This does make finding the right dye for your experiment more complicated. We...ligands with G protein coupled receptors. Biochimica et Biophysica Acta - Biomembranes, 1838(1), 15–33. https...

... norvegicus genes! Mexican axolotl (Ambystoma mexicanum) Ambystoma mexicanum, aka the axolotl. Image...essential aspect of biological research that has defined our understanding of biological processes and developments...studying genetic modification for their ease of manipulation and their ability to be replicated. Because E....providing insight into some of the most significant and fundamental biological processes. Many of their genetics...tools in developmental and biomedical research.  Xenopus, aka African frog. Image from Holger Krisp...Advances on Physiology, Pathogenesis and Biotechnological Applications. InTech. https://doi.org/10.5772/67306...Organism. News-Medical. Retrieved on September 18, 2020 from https://www.news-medical.net/life-sciences...

...the grant application process. When my PhD advisor first asked me to write a grant application due the ...pursue. Proposal writing: Improves technical writing and communication skills, Elucidates the big picture...information required for a successful grant application. It typically includes overview information, key dates...the next round of applications. Step 5: Keep writing! Each written grant application builds upon the ... project grant application" by the NIH Still want more information on the application process? What types...Research at universities typically requires funding from a variety of government and academic institutions...advisor alone applies for these competitive grant applications; however, in some cases, your advisor may choose...

...Other than a theoretical maximum value, physical titers don’t necessarily give any indication of the infectious... red) report physical titer, which is measured by qPCR.   Physical titer is typically calculated by... you? Physical titer: the concentration of viral particles containing viral genomes. Physical titers ...qPCR or other DNA quantification methods - see below), since each viral particle typically contains one viral...facilities report the physical titer of a viral solution (Figure 2). Because physical titers are used for...titer values. Finally, because physical titer does not give an indication of infectious titer, consider...that can transduce cells. Infectious titers are typically quantified by cell transduction assays. Wild-type...

... of the American Chemical Society 123.48 (2001): 12123-12125. Journal of the American Chemical Society...discovery–a review of theoretical aspects and recent applications." Current Chemical Genomics and Translational...originally developed to treat heavy metal intoxication in chemical warfare [Vilensky & Redman, 2003]). Most...al. "Designing logical codon reassignment–Expanding the chemistry in biology." Chemical Science 6.1 (2015... of a biarsenical− tetracysteine motif determined by NMR spectroscopy." Journal of the American Chemical...laboratory, then FRET experiments are a viable biophysical path to answers. What is FRET and what's it...Fluorescence resonance energy transfer (FRET) is a biophysical interaction between two fluorophores. When the...

...underlying all communications efforts.  Scicomm definitions (as used by Addgene)    Science communication, or science...time engaging with science communication efforts.  Scientific communication or scientific writing is peer...to note that it is the actual communication itself, not the communication method, that determines if something...scientific or science communication. A Tweet is still considered scientific communication if the language is...Series, where we’ll be talking about science communication, best practices in the field, and even getting...getting into some active science communication research.   This summer, we’re making time to talk about ...about my favorite thing - science communication (scicomm)! We have so many fun topics planned for this summer...

...epigenome (the sum of epigenetic modifications across the genome) has been implicated in disease states, and targeting...DNA sequences. Non-editing CRISPR applications direct catalytically dead dCas9 fused to a variety of epigenetic...Preps for Epigenetic Modification Why use epigenetic modifiers? Epigenetic modification is certainly not ...Nature Communications 8: . https://doi.org/10.1038/ncomms16026 Find plasmids from this publication at Addgene..., 2017 and updated Jun 24, 2020. Epigenetic modifications are an additional layer of control over gene...efficient. In general, epigenetic chromatin modifications are correlated with alterations in gene expression...mechanisms remain unclear. Today, targeted epigenetic modification at specific genomic loci is possible using CRISPR...