We narrowed to 372 results for: RELA
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TypeBlog PostPublishedJune 15, 2023, 1:15 p.m....which can help determine structure and function relationships or, in more practical applications, allow a ... any of a huge variety of ncAAs to study the relationship between structure and function…if you can get...
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Viral Vectors 101: Types of viruses
TypeBlog PostPublishedJune 6, 2023, 1:15 p.m....lentivirus and gamma-retrovirus are so closely related, their required components are very similar. While...induce a lower inflammatory response within hosts. Relative to the other viruses discussed in this article... -
GPCRs: How Do They Work and How Do We Study Them?
TypeBlog PostPublishedFeb. 11, 2021, 2:15 p.m.... GPCRs for chemogenetic studies to probe the relationship between neurons and specific behaviors. Chemogenetics...DREADDs are ideal for chemogenetics as they are relatively insensitive to their endogenous ligand, acetylcholine... -
Behind the scenes: Addgene’s new search engine and more
TypeBlog PostPublishedDec. 12, 2019, 2:22 p.m....adding more terms. Weighting We determined the relative importance of different bits of information for...shortcuts to specific catalog items as well as related items (for example, a kit that contains a plasmid... -
Back to Bacteria: CRISPR gRNA Multiplexing Using tRNAs
TypeBlog PostPublishedJune 2, 2015, 6:06 p.m.... promoter, gRNA and pol III terminator. These relatively large cassettes (considering the gRNA itself ... vector. In addition, the pol III promoter is relatively weak, and low expression of gRNAs from these ... -
Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur
TypeBlog PostPublishedJuly 10, 2014, 7:17 p.m....effort in preparation and practice is directly related to success presenting." A journey from graduate...LabSpaces Blog Find a Buisness Plan Competition Good Relations - PR for the Biotech Business - Posted on Nature.com... -
Rosella: A Fluorescent pH-Biosensor for Studying Autophagy
TypeBlog PostPublishedApril 13, 2017, 2:30 p.m....structures based on morphology. Autophagosomes are relatively easy to identify: double-membraned structures...comprised of two tandem fluorescent proteins: a relatively pH-insensitive RFP variant, DsRed.T3 and a pH-sensitive... -
CRISPRainbow and Genome Visualization
TypeBlog PostPublishedFeb. 28, 2017, 3:30 p.m....simultaneously, they could also monitor the spatial relationship of the two genes over time, at a range of distances...Mbp, with the calculated fluorescent distances correlating with the previously established physical map.... -
RaPID Detection of RNA-protein Interactions
TypeBlog PostPublishedAug. 16, 2018, 12:40 p.m....that promote RNA decay and their upregulation is correlated with poor survival in breast cancer patients.... wild-type sequences and that loss of binding correlated with increased serum iron levels seen in HHCS... -
Antibodies 101: Fab Fragments
TypeBlog PostPublishedSept. 5, 2024, 1:15 p.m....The modularity of antibodies means that it is relatively easy to physically divide up the different regions...fragments intended for use as primary antibodies are relatively uncommon. Though, if you want to use Fab fragments... -
To Each HIS Own
TypeBlog PostPublishedMarch 2, 2023, 2:15 p.m....binding of untagged proteins. Despite being a relatively low frequency amino acid, proteins containing...questions about polyhistidine tags. For more antibody-related information, sign up to receive alerts for antibody... -
Antibodies 101: Affinity Reagents
TypeBlog PostPublishedApril 14, 2022, 1:15 p.m....antibodies to antibody fragments to tools completely unrelated to antibodies. Why use an alternative affinity... These are antibody mimics and are not closely related to antibodies. Instead, they are derived from a... -
Announcing the Winners of the 2021 Michael Davidson and Roger Tsien Commemorative Conference Awards
TypeBlog PostPublishedAug. 5, 2021, 12:15 p.m....functional contribution to a variety of behaviors related to addiction and pain. Once these are completed...neurons using GCaMP7, measuring calcium signaling related fluorescence during morphine administration and... -
Writing Scientific Manuscripts: Literature Searching, Reading, & Organizing
TypeBlog PostPublishedMay 5, 2015, 3:54 p.m....have to become familiar with a body of literature related to the topic. Finding reliable references and sorting...should give a critical eye to all results in the relation to how they are supporting the conclusions. Look... -
Overcoming the Challenges of Lentiviral Production
TypeBlog PostPublishedAug. 7, 2018, 12:31 p.m....example, while the PEG precipitation method is relatively inexpensive and does not require an ultracentrifuge...titering. Typically researchers will choose a relatively permissive cell line for titering in order to... -
Educational Planarian Tools for Teaching Developmental Biology Techniques
TypeBlog PostPublishedMay 24, 2018, 1:20 p.m....gene expression and functions of key regeneration-related genes in four inexpensive and commercially available... was first discovered and characterized in an unrelated worm (C. elegans) [2]. Delivering dsRNA matching... -
Antibodies 101: Choosing the Right Isotype
TypeBlog PostPublishedApril 6, 2023, 3 p.m.... choose primary antibodies from more distantly related species and/or use narrowly specific secondary ... antibodies raised in different, and distantly related, species, and secondary antibodies raised in the... -
CRISPR Activators: A Comparison Between dCas9-VP64, SAM, SunTag, VPR, and More!
TypeBlog PostPublishedOct. 6, 2020, 1:15 p.m....generation” CRISPR activator. While it requires a relatively simple construct, it exhibits modest levels of...construction: it relies on antibody chains, which are relatively large and are not expressed consistently throughout... -
Tips for Technical Support Calls
TypeBlog PostPublishedSept. 20, 2016, 2:39 p.m....these tips and tricks will apply to any biology-related customer support interaction. Before contacting...support scientists wear many hats at this still relatively small nonprofit. If you do go longer than a few... -
Reaching out to China: Canton Nucleic Acids Forum (CNAF) 2015
TypeBlog PostPublishedDec. 1, 2015, 3:30 p.m....City The conference was located in the modern, relatively new “Science City” area on the outskirts of Guangzhouon...of Georgia studies the CRISPR/Cas system as it relates to its natural role in prokaryotic immunity to ...