We narrowed to 456 results for: val
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TypeBlog PostPublishedFeb. 7, 2023, 2:15 p.m...., the place for scientists to share their AAV validation data. The Data Hub contains a curated collection... Submitting to the Data Hub If you've ever validated an Addgene or CLOVER AAV, you can (and dare we...
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More Data for You: Find Articles Citing Addgene Plasmids
TypeBlog PostPublishedJune 16, 2015, 2:15 p.m....and see what experimental systems it has been validated in. If a plasmid's Addgene ID # has been referenced...dropdown to increase the length of the list (purple oval in the screenshot below). You can also use the "... -
Keeping Up With CRISPR/Cas9
TypeBlog PostPublishedMarch 11, 2014, 5:55 p.m...., targeted genetic modification in monkeys is invaluable for the generation of human disease models." .... Cell. 2014 January 30. (Pubmed) Programmable Removal of Bacterial Strains by Use of Genome-Targeting... -
What's New in CRISPR - Spring 2019
TypeBlog PostPublishedMarch 21, 2019, 12:47 p.m.... CRISPR-based method for cell lineage tracing Valcyrie is a CRISPR-based marker excision method for marking...target. Read the paper in Development Find the Valcyrie plasmids If you have a new CRISPR tool you’ve... -
Why Do I Need an MTA Anyway?
TypeBlog PostPublishedMay 1, 2014, 8:23 p.m....we are here to make it fast and easy. Fast Approval: The UBMTA used by Addgene is internationally ...and familiarity with the UBMTA result in quick approvals, so your plasmid requests can get to your lab ... -
CRISPR Kinome Libraries Available: Pooled and Individual Plasmid Formats
TypeBlog PostPublishedSept. 9, 2016, 2:43 p.m....few positive control genes on which to test the validity of your biological model and the technical performance...Our New and Improved Pooled Library Page Find Validated gRNAs Deposit Your CRISPR Plasmids ... -
A new platform for fast functional characterization of potentially cancerous mutations
TypeBlog PostPublishedMay 7, 2019, 12:39 p.m....available methods for investigating and functionally validating the thousands of mutations that might play a ...over 800) of them had not yet been functionally validated. In vitro assay allows first-time functional annotation... -
Addgene is Expanding Our Viral Vector Service!
TypeBlog PostPublishedOct. 15, 2024, 1:15 p.m....request will be reviewed by Addgene for legal approvals and technical compatibility with our production...not need to be placed immediately upon request approval. Once approved, the request will remain in your... -
Supporting Rare Disease Research with BeHeard 2017
TypeBlog PostPublishedJuly 20, 2017, 2:30 p.m....tumorigenesis. These experiments will serve to validate these candidate genes and allow Nabavi and colleagues...PP09. 1–2352: Systematic review of incidence and prevalence of spinal muscular atrophy (SMA)." European Journal... -
A Better Way to Get Customer Support: The Help Center
TypeBlog PostPublishedDec. 10, 2015, 3:30 p.m....Addgene, we certainly hope not! One of our core values here is to provide unmatched customer support, ...improving the support we provide based on your valuable feedback. This is Addgene after all, and making... -
Mapping the 4D nucleome with CRISPR/Cas9
TypeBlog PostPublishedAug. 11, 2015, 2:30 p.m....targets ~2 Mbp apart, they noticed that they could evaluate the degree of chromatin compaction even for this...imaging. Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. Cell. 2014 Oct 23;159(3):635-46. doi: 10.1016... -
Future of Research Conference - Remarkable Opening Session
TypeBlog PostPublishedOct. 7, 2014, 3 p.m....is unsustainable, hypercompetition is corroding values, we are shifting away from PI driven basic research...science careers. She advocated for increasing the value and priority put on good mentoring and applauded... -
CASTing Off for New Shores in Human Genome Editing
TypeBlog PostPublishedJune 10, 2025, 1:15 p.m....transposons open whole new worlds to explore. The newest arrival on the scene is called evoCAST — an evolved CRISPR-associated...individualized optimizations, safety testing, and approval. In contrast, a system that can deliver a healthy... -
Cellosaurus: A Cell Line Information Database
TypeBlog PostPublishedFeb. 21, 2023, 2:15 p.m....reproducibility of scientific data depends on validated reagents along with clear documentation, so we...programatically, their API allows fine grained query and retrieval of all the information in the resource. This ... -
Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation
TypeBlog PostPublishedMay 21, 2020, 1:15 p.m....using chemical inducers of gene expression (del Valle Rodríguez et al., 2011). Genetics of SPARC ...generalizable to other systems as well. References: del Valle Rodríguez A, Didiano D, Desplan C (2011) Power tools... -
New CRISPR Web Resources and #12DaysofCRISPR Recap
TypeBlog PostPublishedDec. 12, 2017, 3:13 p.m....Editing with CRISPR-Cpf1 Day 4: Edit validation: CRISPR 101: Validating Your Genomic Edit and Sequencing ... -
Sleeping Beauty Awakens for Genome Engineering
TypeBlog PostPublishedJune 30, 2015, 2 p.m....). The original plasmid is empty following the removal of the transposon; the plasmid is then degraded...chimeric antigen receptor (CAR) therapy. SB is a valuable tool and an alternative to CRISPRs for genome ... -
Advice for Choosing a Research Project
TypeBlog PostPublishedApril 17, 2014, 2:45 p.m....especially you!) care about. Have you critically evaluated your plan? Have you read the relevant literature... doing the same experiment for too long. Keep evaluating your project along the way. Advice from principal... -
Multifunctional Neural Fibers: Modulation from Gut to Brain
TypeBlog PostPublishedAug. 31, 2023, 1 p.m....developed multifunctional fibers, embedded, and validated simultaneously in the brain and the intestines...expression of the opsin in the target neurons, validating the functionality of these inputs and outputs... -
Antibodies 101: Epitope Tags
TypeBlog PostPublishedMay 11, 2023, 1:15 p.m....Myc was developed in 1985 and is still the most prevalent clone used today! Goat, chicken, mouse, or rabbit... brought about by the tag so it’s important to validate tagged protein functionality (Arribere, et al)...