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...hypothesis was that trained muscle would produce a substance with beneficial effects on the brain,” Ruas said...produces an enzyme that purges the body of harmful substances. So in this context the muscle's function is ...

... A KTR is comprised of a fluorescently-tagged substrate for a kinase of interest which is further fused... used to measure kinase activity in specific subcellular compartments. Second, because KTRs shuttle between...

...Experiments by Jennifer Tsang Chromoproteins are a subset of the fluorescent protein family and they generate...molecular biology tools out there! Here, we highlight a subset of these tools for plasmid mapping, DNA/protein...

...targeting the mouse and human kinomes. While any subset of the genome is limited by definition, the kinome...plasmids contain the same 3-4 gRNAs found in the first subset of the pooled library. The individual plasmids ...

...a few species of bacteria and sometimes, only a subset of strains of the same bacterial species are affected...developments at Phage Directory and in the phage field, subscribe to their newsletter, Capsid and Tail. Additional...

...once science was only seen as a serious academic subject, it is now being appreciated on an aesthetic level...which could promote conservation efforts, as the subject matter is seen to have increased value and is appreciated...

...locus may be useful to study haploinsufficiency. Subsequent modifications at the remaining allele within ... Lin C, et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin...

...expectations were for the intended position. After submitting my application, I was contacted to participate...discrepancies between what we sequenced in house and the submitted sequences were a concern to the plasmid function...

...or antibodies against common tumor markers to subsequently capture cancerous cells expressing low levels...depositing your plasmids with Addgene. Howarth: We submit all our plasmids that may well be of use to others...

...determine potential water contaminants and to subsequently develop technologies to protect fresh water ...Labs Plasmid Grant awardees' projects progress. Subscribe to the Addgene blog for updates and future collaborations...

...dopaminergic neurons in a brain region called the substantia nigra, which is the main source of the body’s...sensor, dLight1.1 and dLight1.2, exhibit high (submicromolar) DA affinity and high-magnitude responses (increases...

...just a fraction of a single genetically-defined subset of cells. By labeling fewer cells in a population... genetic tool that allows for the labeling of a subset of cells with the same genetic makeup, overcomes...

...popularity of single-use items, plastic is a substantial portion of lab waste. Despite the fact that researchers...PMC5517107. Additional resources on the Addgene blog Subscribe to the Addgene blog Find lab tips for your research...

...serves to stabilize DNA-protein interactions for subsequent sheering of DNA by sonification. Though it helps... short DNA fragments can then be purified for subsequent library preparation and high-throughput sequencing...

...prefer to be approached as peers rather than subordinates Need mental space and dislike intrusions (this...Introduction to Managing People for Scientists. Subscribe to the Addgene Blog to follow the entire series...

...reasons to feel obligated too, as experts on the subject brought out in a Kavli Foundation Round Table. ... be a good way to follow news about particular subjects or find out what others are reading. Check out...

... deposit agreement must be put in place. And subsequently, every time that material is requested, a material...find some easy talking points for broaching this subject with your institution’s tech transfer professionals...

...Karolinska Institute developed mNeonGreen via 21 substitutions to LanYFP and the addition of the enhanced GFP...choosing fluorescent proteins for your research Subscribe to the Addgene blog Resources on Addgene.org ...

...to what the research had to say. Moreover, this subject allowed me to engage in findings relevant to my...areas in which I knew very little. Diving into subjects like risk perception, scientific uncertainty and...

...Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids...labeling just a fraction of a genetically-defined subset of cells. By labeling fewer cells in a population...