We narrowed to 102 results for: LEA

...-pre-mGRASP-mCerulean CAG-driven, constitutive Expression of pre-synaptic mGRASP-mCerulean for synaptic...Genome Engineering Tools These AAV encode Cas9 nuclease used in the CRISPR-Cas9 system for targeted genome...would like to see available in viral prep format. Please note this does not guarantee viral vector packaging...

...pCS2plus-mCerulean 156-239-GGGS-TDP-43 TARDBP mCerulean CMV ALS Marco Morsch 162618 pCS2plus-mCerulean 156-...Parkinson's, FTD Michael Davidson 55431 mCerulean3-MAPTau-C-10 MAPT mCerulean3 CMV Parkinson's, FTD Michael Davidson...Sidhu 110061 pDUET-1-alpha-synuclein-mCerulean3-His6 SNCA His, mCerulean3 T7 Parkinson's Dan Mulvihill 110486...Lippincott-Schwartz 164214 PLEX-PGK-ANXA11-mCerulean ANXA11 mCerulean PGK ALS Jennifer Lippincott-Schwartz ...mRuby CMV ALS Jennifer Lee 216227 TDP-43 mCerulean TARDBP mCerulean CMV ALS Jennifer Lee 216709 pCAG-TSF-...If you do not see a particular gene of interest, please search our full plasmid collection using the search...Bacterial Yeast Other Promoter CMV T7 polH GAL Other Clear Filters ID Plasmid Name Gene Tags Promoter Disease...

...Deisseroth AV-1-PV3248 105557-AAV1 pENN.AAV.CB7.CI.mCerulean.WPRE.RBG Control James M. Wilson AV-1-PV3508 98928...Wickersham AV-9-PV3248 105557-AAV9 pENN.AAV.CB7.CI.mCerulean.WPRE.RBG Control James M. Wilson AV-1-PV1090 105537...Plasmids are available for all the items listed below. Please let us know (Link opens in a new window) what you...you would like to see available in viral format. Please note this does not guarantee viral service, but...pENN.AAV.CB7.CI.TurboRFP.WPRE.RBG James M. Wilson Please contact [email protected] with any questions. Return...

...pathogenic Xanthomonas spp. to the FokI nuclease, TALENs bind and cleave DNA in pairs. Binding specificity ...DNA-binding domain of a TALE, along with strong nuclear localisation tags and repress transcription initiation... BioSciences (N153AA, C63AA) and showed robust cleavage activity in several later studies. pCAG-T7-TALEN...

...Luciferase catalyzes the oxidation of a substrate, leading to the emission of photons. Its robust signal, ...sensitivity, wide dynamic range, and resistance to photobleaching have made luciferase a popular tool for scientists...making it ideal for a variety of applications. To learn more and plan your experiment, read our Luciferase...Artificial luciferases desined de novo using deep-learning approaches. Split Luciferase Complementation assays...

...mice use LY6A to cross the blood-brain barrier, leading to strain-specific tropism (See S3 table (Huang...review performance data of each of these serotypes, please refer to Addgene’s Data Hub and the Caltech CLOVER...using the Caltech serotypes in future publications, please acknowledge Viviana Gradinaru and cite as follows...would like to see available in viral prep format. Please note this does not guarantee viral vector packaging...

...Use this guide to learn about the applications of fluorescent proteins and to find the plasmids that ...fluorescent protein plasmids. Use this guide to learn more about the many applications of fluorescent ... gene expression, signaling pathways, and more. Learn More and Explore Addgene Blog: Fluorescent Proteins...

...insertions or deletions (indels) in the DNA. Indels often lead to frameshifts, creating loss of function alleles.... Figure 1: Overview of NHEJ and HDR following cleavage by Cas9. Browse, sort, or search the tables below...CRISPR plasmids designed to introduce a DSB. To learn more about NHEJ, HDR, and other CRISPR topics, read...

...Learn about PRISM, a set of molecular tools for high-throughput reconstruction of individual neurons ...these protein barcodes allow for efficient machine-learning segmentation of neurons and proofreading of neuron...microscopy and reconstruction of neurons with machine learning. Adapted from Park & Sheridan et al. (2025). PRISM...

...mCherry-LaminA-C-18 Nuclear envelope LaminA1 mCherry* Michael Davidson 98830 mTurquoise2-LaminB Nuclear envelope ...mTurquoise2 Dorus Gadella 55069 mCherry-LaminB1-10 Nuclear envelope LaminB1 mCherry* Michael Davidson 98822...mKalama1 Robert Campbell 189776 pmScarlet3-LaminB_C1 Nuclear envelope LaminB1 mScarlet3 Dorus Gadella 231782...

...Serotype AAV1 AAV2 AAV5 AAV8 AAV9 Retrograde AAV PHPeB Clear Filters ID Name Receptor and Activity Reporter/Tag...available items found to match all requested criteria. Please consider using fewer filtering options. *AAVrg ...would like to see available in viral prep format. Please note this does not guarantee viral vector packaging...

...Genomic Sequences To perform genome edits, Cas9 nuclease is used to generate double-stranded breaks ( DSBs...Suggestions Don’t see what you are looking for? Please let us know what you would like to see available... Suggestion Form (Link opens in a new window) . Please note this does not guarantee viral service, but...

...site-specific recombination, morpholinos, zinc finger nucleases, TALENS, and CRISPR/Cas9-based gene editing make...Highlights of Zebrafish Tools in our Collection CRISPR Please refer to Addgene's CRISPR Guide for a general introduction...Cas9 - Jeffrey Essner Lab CRISPR-Cas/RNA-Guided Nuclease (RGN) expression plasmids - Keith Joung Lab CRISPR...

...10aa-H2B-WPRE3-BGHpA AAV vector for nuclear SYFP2 labeling in neurons. Useful for nuclear isolation and scRNA-seq ...SYFP2 (yellow fluorescent protein) plus separate nuclear FLAG epitope in striatal cholinergic neurons Jonathan...

...plasmids The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun...and Sox2 Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs. Cell Stem...Baldwin Fibroblasts iTSCs Lentiviral Mouse Extensive Nuclear Reprogramming Underlies Lineage Conversion into...

...Learn about tetracycline-regulated gene expression and find plasmids for your experiments using tet- ...dox) is present, TetR binds to tetracycline and releases tet O, enabling transcription (Figure 1). While...tet-responsive systems: Tet-Off and Tet-On. Read on to learn more about the components of tet systems and how...

...Serotype AAV1 AAV2 AAV5 AAV8 AAV9 Retrograde AAV PHPeB Clear Filters ID Name Promoter Sensor Label Activity Serotype...available items found to match all requested criteria. Please consider using fewer filtering options. *AAVrg ...would like to see available in viral prep format. Please note this does not guarantee viral vector packaging...

...Consortium (SGC) Plasmids Haian Fu Lab plasmids Opher Gileadi Lab plasmids (Link opens in a new window) The TREAT-AD...AD and creating high-quality, well-characterized lead molecules for prioritized targets that are valued...

... method Nuclease Expression Vectors - Cloning vectors for expressing zinc finger FokI nuclease fusions...

...repair (HDR). Figure 1: Overview of Cas9 nickase cleavage and repair. Browse, sort, or search the tables...tables below for CRISPR nickase plasmids. To learn more about CRISPR nickases and other CRISPR topics, read...