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We narrowed to 2 results for: halo tag

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  1. Optogenetics Guide

    Type
    Guide
    ...light-inducible dimerization tags; proteins fused to LOVpep reversibly dimerize with PDZ tags (cpPDZ, ePDZb, or ...silence neuronal activity 632 Halo/NpHR Light-driven inward chloride pump from Natronomonas pharaonis ,... , used to silence neuronal activity; Halo is human codon-optimized 589 eNpHR, eNpHR2.0, eNpHR3.0 eNpHR...the cryptophyte Guillardia theta ). Halorhodopsins Halorhodopsins are light-gated, inward-directed chloride...chloride pumps isolated from halobacteria. Wild-type halorhodopsin, known as NpHR (from Natronomonas pharaoni...light-driven inward chloride pump from Haloarcula (Halobacterium) salinarum (strain Shark), used to silence...activation wavelengths, which may have advantages or disadvantages depending on the equipment available ...
  2. Adeno-associated virus (AAV) Guide

    Type
    Guide
    ...reducing the risk of immune activation, both key advantages of rAAV vectors. AAV Types Serotypes AAV serotypes...immune response, and the low risk of insertional mutagenesis. Several AAV-based gene therapies have been approved...short coding sequences of channelrhodopsins, halorhodopsins, and other optogenetic genes makes them suitable...chromosome, which reduces the risk of insertional mutagenesis. However, random integration events can occur...host organism, leading to disease. Insertional mutagenesis Random insertion of DNA elements into the genome...
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